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List of substances for condition Group: Digestive System

All Human Animal Risk/Association ReviewRows: 716

Substance InfoDose WarnLink PubMed
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Curcumin 📋38674895The Possible Synergistic Pharmacological Effect of an Oral Berberine (BBR) and Curcumin (CUR) Complementary Therapy Alleviates Symptoms of Irritable Bowel Syndrome (IBS): Results from a Real-Life, Routine Clinical Practice Settings-Based Study
Berberine 📋38729536Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells
Vitamin D3 📋38732118Vitamin D and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Novel Mechanistic Insights
Resveratrol 📋38682953Resveratrol triggers autophagy-related apoptosis to inhibit the progression of colorectal cancer via inhibition of FOXQ1
Ginsenosides 📋38698858Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system
Melatonin 📋38674926Mechanism of Action of Melatonin as a Potential Adjuvant Therapy in Inflammatory Bowel Disease and Colorectal Cancer
Quercetin 📋38677479Higher dietary quercetin intake is associated with lower risk of adverse outcomes among individuals with inflammatory bowel disease in a prospective cohort study
EGCG 📋38607257Tea Polyphenol Epigallocatechin Gallate Protects Against Nonalcoholic Fatty Liver Disease and Associated Endotoxemia in Rats via Modulating Gut Microbiota Dysbiosis and Alleviating Intestinal Barrier Dysfunction and Related Inflammation
Vitamin C 📋38635545Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States
Metformin 📋38530777Metformin boosts anti-tumor immunity and improves prognosis in upfront resected pancreatic cancer: an observational study
Sulforaphane 📋38721140Sulforaphane protects against LPS-induced liver injury in mice by antagonizing oxidative stress and apoptosis through AMPK activation
Probiotics 📋38542689Prebiotics and Probiotics for Gastrointestinal Disorders
Omega-3 Fatty Acids 📋38712398Gallstone Dissolution Effects of Combination Therapy with n-3 Polyunsaturated Fatty Acids and Ursodeoxycholic Acid: A Randomized, Prospective, Preliminary Clinical Trial
Ginseng 📋38698858Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system
Luteolin 📋38674851Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention
Vitamin E 📋38540888The Potential Role of Vitamin E and the Mechanism in the Prevention and Treatment of Inflammatory Bowel Disease
Silymarin 📋38726410Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases-A comprehensive narrative review
Fucoidan 📋38064857Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice
Apigenin 📋38619972Apigenin Suppresses MED28-Mediated Cell Growth in Human Liver Cancer Cells
Goji Berry 📋38576495Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase
Lycopene 📋38544357Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway
Astaxanthin 📋38692895Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis Residue Alleviate Liver Injury in D-Galactose-induced Aging Mice through Gut-liver Axis
Pterostilbene 📋38518635Pterostilbene suppresses gastric cancer proliferation and metastasis by inhibiting oncogenic JAK2/STAT3 signaling: In vitro and in vivo therapeutic intervention
Cannabidiol 📋38711461Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways
Ellagic Acid 📋38671932Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Astragalosides 📋38689349Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier
Reishi Mushrooms 📋38451046Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity
Medicinal Plants 📋 38464716The additive effect of herbal medicines on lifestyle modification in the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis
Genistein 📋38592519Genistein alleviates dextran sulfate sodium-induced colitis in mice through modulation of intestinal microbiota and macrophage polarization
Baicalein 📋38727775Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model
Emodin 📋 38704789Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation
Andrographolide 📋 38467318Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees
Grape Seed extract 📋38419408Grape seed extract supplementation in non-alcoholic fatty liver disease
Baicalin 📋38730240Baicalin enhances the chemotherapy sensitivity of oxaliplatin-resistant gastric cancer cells by activating p53-mediated ferroptosis
Silibinin 📋 38222315Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis
Thymoquinone 📋 38652404N-methyl-D-aspartate receptors and thymoquinone induce apoptosis and alteration in mitochondria in colorectal cancer cells
Astragalus Root 📋38621911[Astragali Radix-Curcumae Rhizoma inhibits colon cancer progression and enhances 5-FU efficacy by regulating hypoxia-inducible factors and tumor stem cells]
Kaempferol 📋38596072Kaempferol-induced mitochondrial damage promotes NF-κB-NLRP3-caspase-1 signaling axis-mediated pyroptosis in gastric cancer cells
Zinc 📋38012749The effects of zinc supplementation on the metabolic factors in patients with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled clinical trial
Hesperidin 📋38477785Protective effects of hesperidin in gastric damage caused by experimental ischemia-reperfusion injury model in rats
N-Acetyl Cysteine 📋38540289The Use and Potential Benefits of N-Acetylcysteine in Non-Acetaminophen Acute Liver Failure: An Etiology-Based Review
Bee Propolis 📋38710295Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials
Licorice Root 📋38641080Wighteone, a prenylated flavonoid from licorice, inhibits growth of SW480 colorectal cancer cells by allosteric inhibition of Akt
Ginger 📋38461442Effect of ginger and P6 acupressure on chemotherapy-induced nausea and vomiting: a randomized controlled study
Nobiletin 📋 38547624Nobiletin targets SREBP1/ACLY to induce autophagy-dependent cell death of gastric cancer cells through PI3K/Akt/mTOR signaling pathway
Anthocyanins 📋38290991Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells
Phytochemicals 📋 38690008A comprehensive review on phytochemicals in the treatment and prevention of pancreatic cancer: Focusing on their mechanism of action
Selenium 📋38691983Genetic prediction of micronutrient levels and the risk of colorectal polyps: A mendelian randomization study
Fisetin 📋38191834Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS-induced murine model of colitis
Aloe Vera 📋38595509Efficacy of Aloe Vera, Amlexanox (5%), and Triamcinolone Acetonide (0.1%) in the Management of Oral Lichen Planus
Butyrate 📋 38533461The postbiotic sodium butyrate synergizes the antiproliferative effects of dexamethasone against the AGS gastric adenocarcinoma cells
Gingerol 📋 385655696-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway
Naringenin 📋38583080A narrative review on therapeutic potential of naringenin in colorectal cancer: Focusing on molecular and biochemical processes
Nigella Sativa 📋38578469Determination of anti-cancer effects of Nigella sativa seed oil on MCF7 breast and AGS gastric cancer cells
Aspirin 📋 38601481Effects of aspirin on colon cancer using quantitative proteomic analysis
Food 📋 38329234Causal relationships between dietary habits and Barrett's esophagus risk: a univariable and multivariable Mendelian randomization study
Micronutrients 📋 38703282A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways
Peppermint Essential Oil 📋38331851Efficacy and safety of peppermint oil for the treatment in Japanese patients with irritable bowel syndrome: a prospective, open-label, and single-arm study
Piperine 📋38547097Piperine alleviates nonalcoholic steatohepatitis by inhibiting NF-κB-mediated hepatocyte pyroptosis
Pomegranate 📋 38661445Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites
Dandelion 📋38568379Potentialities of dandelion (Taraxacum mongolicum Hand.-Mazz.) flower extracts on gastric protection against Helicobacter pylori and characterization of its bioactive constituents
Moringa Oleifera 📋38493756Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers
Gallic Acid 📋 38636693Gallic acid mitigates intestinal inflammation and loss of tight junction protein expression using a 2D-Caco-2 and RAW 264.7 co-culture model
L-Glutamine 📋38656560L-Glutamine Substantially Improves 5-Fluorouracil-Induced Intestinal Mucositis by Modulating Gut Microbiota and Maintaining the Integrity of the Gut Barrier in Mice
Mulberry 📋 38707917Mulberry leaf extract inhibits obesity and protects against diethylnitrosamine-induced hepatocellular carcinoma in rats
Dihydromyricetin 📋38532480Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway
Fish Oil 📋38486044Fish oil ameliorates ethanol-induced gastric injury in rat by modulating gene related to apoptosis
Green Tea Polyphenols 📋37085597Green tea extract prevents CPT-11-induced diarrhea by regulating the gut microbiota
Magnesium 📋38509591Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma
Pomegranate Peel extract 📋38107049Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma ( in vitro study)
Puerarin 📋38674860Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice
Salidroside 📋 38436092Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules
Spirulina 📋38694088Amino acid HPLC-FLD analysis of spirulina and its protective mechanism against the combination of obesity and colitis in wistar rats
Capsaicin 📋38706122Capsaicin reverses cisplatin resistance in tongue squamous cell carcinoma by inhibiting the Warburg effect and facilitating mitochondrial-dependent apoptosis via the AMPK/AKT/mTOR axis
Dihydroartemisinin 📋 38713259Target prediction and potential application of dihydroartemisinin on hepatocarcinoma treatment
Kiwifruit 📋38144866Lactiplantibacillus plantarum fermentation enhanced the protective effect of kiwifruit on intestinal injury in rats: Based on mitochondrial morphology and function
Licochalcones 📋 38148556Licochalcone C Inhibits the Growth of Human Colorectal Cancer HCT116 Cells Resistant to Oxaliplatin
Walnut 📋 38068724The Gastroprotective Effect of Walnut Peptides: Mechanisms and Impact on Ethanol-Induced Acute Gastric Mucosal Injury in Mice
Chlorogenic Acid 📋38708558Chlorogenic acid and its isomers attenuate NAFLD by mitigating lipid accumulation in oleic acid-induced HepG2 cells and high-fat diet- fed zebrafish
Chrysin 📋37167529Chrysin prevents inflammation-coinciding liver steatosis via AMPK signalling
Naringin 📋38557865Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation
Paeoniflorin 📋 38634140Activation of ASIC3/ERK pathway by paeoniflorin improves intestinal fluid metabolism and visceral sensitivity in slow transit constipated rats
Blueberry 📋38107049Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma ( in vitro study)
Crocin 📋37718528Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
Skullcap 📋38616754Network Pharmacology, Molecular Docking Analysis and Molecular Dynamics Simulation of Scutellaria baicalensis in the Treatment of Liver Fibrosis
Apple 📋 37129213Apple juice relieves loperamide-induced constipation in rats by downregulating the intestinal apical sodium-dependent bile acid transporter ASBT
Indian Gooseberry 📋 38158054Phyllanthus emblica L. polysaccharides ameliorate colitis via microbiota modulation and dual inhibition of the RAGE/NF-κB and MAPKs signaling pathways in rats
Inulin 📋38473746Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease
TUDCA 📋38192027Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner
Glycyrrhizic Acid 📋38700384Glycyrrhizic acid attenuates the malignant biological properties of nonalcoholic fatty liver disease-related hepatocellular carcinoma
Polyphenols 📋 38625672Liver cancer wars: plant-derived polyphenols strike back
Fucoxanthin 📋38669300Molecular Mechanisms of Fucoxanthin in Alleviating Lipid Deposition in Metabolic Associated Fatty Liver Disease
Galangin 📋 38602402Galangin Prevents Against Ethanol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation via NF-κB/MAPK Signaling Pathways in Mice and Caco-2 Cells
Ginger extract 📋36865747Oral Administration Evaluation of the Hydro-Ethanolic Extract of Ginger (Rhizome of Zingiber officinale) against Postoperative-Induced Peritoneal Adhesion: Investigating the Role of Anti-Inflammatory and Antioxidative Effects
Turmeric 📋38621911[Astragali Radix-Curcumae Rhizoma inhibits colon cancer progression and enhances 5-FU efficacy by regulating hypoxia-inducible factors and tumor stem cells]
Allicin 📋38728949Allicin regulates Sestrin2 ubiquitination to affect macrophage autophagy and senescence, thus inhibiting the growth of hepatoma cells
Docosahexaenoic Acid 📋38430210Docosahexaenoic Acid Modulates Nonalcoholic Fatty Liver Disease by Suppressing Endocannabinoid System
Psyllium 📋36828279PSYLLIUM FIBER PROTECTS AGAINST COLITIS VIA ACTIVATION OF BILE ACID SENSOR FXR
Schisandra 📋38585559A combined extract containing Schisandra chinensis (SCE) reduced hepatic triglyceride accumulation in rats fed a high-sucrose diet
Vitamin A 📋38492186Immunomodulatory and Anti-Inflammatory Effects of Vitamin A and Tryptophan on Monocyte-Derived Dendritic Cells Stimulated with Gliadin in Celiac Disease Patients
Wogonin 📋38518634Wogonin improves colitis by activating the AhR pathway to regulate the plasticity of ILC3/ILC1
Arctigenin 📋 38679116Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice
Ginkgo Biloba 📋38727268L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism
Lipoic Acid 📋38245790(+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease
Raspberry 📋38340928Raspberry polysaccharides attenuate hepatic inflammation and oxidative stress in diet-induced obese mice by enhancing butyrate-mediated intestinal barrier function
Beta-Carotene 📋38691983Genetic prediction of micronutrient levels and the risk of colorectal polyps: A mendelian randomization study
Garlic 📋38223588Garlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials
Patchouli 📋37513952Probiotic Formulations Containing Fixed and Essential Oils Ameliorates SIBO-Induced Gut Dysbiosis in Rats
Tanshinone 📋 38621946[Tanshinone â…¡_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]
Atractylodes 📋38663104The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats
Coffee 📋38346920Coffee consumption is associated with a reduced risk of colorectal cancer recurrence and all-cause mortality
Cranberry 📋38139823Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model
Rutin 📋38394735Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway
Honokiol 📋 38402928The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity
Lactobacillus plantarum 📋 38528541Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis
Coptis Chinensis 📋 38729536Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells
Flavonoids 📋 38700837Harnessing Plant Flavonoids to Fight Pancreatic Cancer
Honey 📋38710295Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials
CoQ10 📋37701221The effect of coenzyme Q10 supplementation on liver enzymes: A systematic review and meta-analysis of randomized clinical trials
Maitake Mushrooms 📋 37351508Mushroom polysaccharides from Grifola frondosa (Dicks.) Gray and Inonotus obliquus (Fr.) Pilat ameliorated dextran sulfate sodium-induced colitis in mice by global modulation of systemic metabolism and the gut microbiota
Chokeberry 📋36344052Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota
Cordycepin 📋 38589021Cordycepin Enhanced Therapeutic Potential of Gemcitabine against Cholangiocarcinoma via Downregulating Cancer Stem-Like Properties
Green Tea 📋38370081Long-term drinking of green tea combined with exercise improves hepatic steatosis and obesity in male mice induced by high-fat diet
Rosmarinic Acid 📋 37749237Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis
Bromelain 📋37803248Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells
Cinnamon 📋38466698Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses
Grape 📋 37511015Synergistic Effects of Vitis vinifera L. and Centella asiatica against CCl4-Induced Liver Injury in Mice
Hesperetin 📋 37109513Hesperetin and Capecitabine Abate 1,2 Dimethylhydrazine-Induced Colon Carcinogenesis in Wistar Rats via Suppressing Oxidative Stress and Enhancing Antioxidant, Anti-Inflammatory and Apoptotic Actions
L-Carnitine 📋38727268L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism
Prebiotics 📋38613035Prebiotic Strategies to Manage Lactose Intolerance Symptoms
Schisandrins 📋 38500179The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
Urolithins 📋 38622949Urolithin A affects cellular migration and modulates matrix metalloproteinase expression in colorectal cancer cells
Caffeine 📋38680003Evaluation of the Combined Effect of Caffeine and 5-Fluorouracil on Colorectal Cancer Cell Lines
Dihydroquercetin 📋 38552433Dihydroquercetin improves experimental acute liver failure by targeting ferroptosis and mitochondria-mediated apoptosis through the SIRT1/p53 axis
Eugenol 📋 38480500Eugenol Possesses Colitis Protective Effects: Impacts on the TLR4/MyD88/NF-[Formula: see text]B Pathway, Intestinal Epithelial Barrier, and Macrophage Polarization
Ferulic Acid 📋38293309Ferulic acid interventions ameliorate NDEA-CCl4-induced hepatocellular carcinoma via Nrf2 and p53 upregulation and Akt/PKB-NF-κB-TNF-α pathway downregulation in male Wistar rats
Peony 📋 38186470Atractylodes macrocephala-Paeonia lactiflora Class Formula for the Treatment of Irritable Bowel Syndrome: A Systematic Review With Meta-Analysis and Trial Sequential Analysis
Red Sage 📋38636259Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits
Cinnamaldehyde 📋 38663778Cinnamaldehyde: An effective component of Cinnamomum cassia inhibiting Helicobacter pylori
Fiber 📋38730369Exploring the association between dietary fiber intake and hepatic steatosis: insights from NHANES
Hydroxytyrosol 📋 38680105Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition
Nicotinamide Riboside 📋38729053Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease
Olive Oil 📋38493431Evaluation of the protective and therapeutic effects of extra virgin olive oil rich in phenol in experimental model of neonatal necrotizing enterocolitis by clinical disease score, ınflammation, apoptosis, and oxidative stress markers
Salvianolic Acid 📋 38674860Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice
Wormwood 📋38139333Artemisia annua L. Polyphenols Enhance the Anticancer Effect of β-Lapachone in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells
Aloe-Emodin 📋 37956613Aloe-emodin destroys the biofilm of Helicobacter pylori by targeting the outer membrane protein 6
Andrographis 📋38467318Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees
Apple Polyphenols 📋 38055797Preventive Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are Related to the Regulation of Hepatic Lipid Metabolism, Autophagy, and Gut Microbiota in Aged Mice
Chamomile 📋38710295Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials
Diosmin 📋38500992Diosmin alleviates ulcerative colitis in mice by increasing Akkermansia muciniphila abundance, improving intestinal barrier function, and modulating the NF-κB and Nrf2 pathways
Isoliquiritigenin 📋 38671579Isoliquiritigenin limits inflammasome activation of macrophage via docking into Syk to alleviate murine non-alcoholic fatty liver disease
Oleuropein 📋 38436159Oleuropein, a phenolic component of Olea europaea L. ameliorates CCl4-induced liver injury in rats through the regulation of oxidative stress and inflammation
Beta-Glucan 📋38674816Consumption of Feed Supplemented with Oat Beta-Glucan as a Chemopreventive Agent against Colon Cancerogenesis in Rats
Boswellic Acid 📋38513840Acetyl-11-keto-beta-boswellic acid inhibits cell proliferation and growth of oral squamous cell carcinoma via RAB7B-mediated autophagy
Gardenia 📋 38090678Gardenia Iridoid Glucosides Protect Against α-Naphthalene Isothiocya-Nate-Induced Cholestatic Rats Through Activation of the FXR-SHP Signaling Pathway
Mangiferin 📋 38191592Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat's colon by augmentation of apoptotic proteins and antioxidant mechanisms
Tea 📋 37867491Association of tea and its extracts with colorectal adenomas: meta-analysis and systematic review
Carnosic Acid 📋 36979808Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation
Catechins 📋 37732516Catechin hydrate ameliorates cerulein‑induced chronic pancreatitis via the inactivation of TGF‑β/Smad2 signaling
Diosgenin 📋 38458369Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses
Hawthorn 📋38601914A study on the treatment effects of Crataegus pinnatifida polysaccharide on non-alcoholic fatty liver in mice by modulating gut microbiota
NMN 📋38729053Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease
Saffron 📋38146566Effectiveness of the Combination of Probiotic Supplementation on Motor Symptoms and Constipation in Parkinson's Disease
UDCA 📋38712398Gallstone Dissolution Effects of Combination Therapy with n-3 Polyunsaturated Fatty Acids and Ursodeoxycholic Acid: A Randomized, Prospective, Preliminary Clinical Trial
Withaferin A 📋 38537439Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells
Beta-Sitosterol 📋38156844The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis
Betaine 📋38695854Use of Betaine HCl with Pepsin in Esophageal Cancer Patient: A Case Report
Burdock 📋 38018589Long-term oral administration of burdock fructooligosaccharide alleviates DSS-induced colitis in mice by mediating anti-inflammatory effects and protection of intestinal barrier function
Cordyceps 📋38582477Elucidation of antioxidant activities of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective effects on ulcerative colitis in vivo
Frankincense 📋37719039Water extract of frankincense and myrrh inhibits liver cancer progression and epithelial‑mesenchymal transition through Wnt/β‑catenin signaling
Procyanidins 📋 37831732The combined anticancer of peanut skin procyanidins and resveratrol to CACO-2 colorectal cancer cells
Thymol 📋38376297Induction of G0/G1 phase cell cycle arrest and apoptosis by thymol through ROS generation and caspase-9/-3 activation in breast and colorectal cancer cell lines
Alpha-Linolenic Acid 📋38435630Alpha-Linolenic Acid Ameliorates Cognitive Impairment and Liver Damage Caused by Obesity
Amygdalin 📋38680005The Cytotoxic Effect of Ciprofloxacin Laetrile Combination on Esophageal Cancer Cell Line
Black Tea 📋37940573The Effects of Black Tea Consumption on Intestinal Microflora-A Randomized Single-Blind Parallel-Group, Placebo-Controlled Study
Carvacrol 📋38605312The inhibitory effects of carvacrol, nystatin, and their combination on oral candidiasis isolates
Emu Oil 📋37402926Emu Oil and zinc monoglycerolate independently reduce disease severity in a rat model of ulcerative colitis
Geniposide 📋 38069009Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the TLR4 and AMPK Signaling Pathways
Mangosteen 📋36098087Garcinia mangostana and α-Mangostin Revive Ulcerative Colitis-Modified Hepatic Cytochrome P450 Profiles in Mice
Polydatin 📋 36678905Chemopreventive and Anticancer Role of Resveratrol against Oral Squamous Cell Carcinoma
Shogaol 📋 382573326-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress
Taurine 📋38681990Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis
Acai Berry 📋38428258A polyphenol-rich açaí seed extract protects against 5-fluorouracil-induced intestinal mucositis in mice through the TLR-4/MyD88/PI3K/mTOR/NF-κBp65 signaling pathway
Angelica 📋37563852Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver
Artemisinin 📋 38409843Artesunate Inhibits Lipid Accumulation and Inflammation by Regulating the NLRP3 Inflammasome in Nonalcoholic Fatty Liver Disease
Eicosapentaenoic Acid 📋37887366Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study
Flaxseed 📋38398791Beneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease
Pine Bark 📋38600993Effect of pine bark extract and its phenolic compounds on selected pathogenic and probiotic bacterial strains
Punicalagin 📋38455601The synergistic effect of oxaliplatin and punicalagin on colon cancer cells Caco-2 death
Bee Venom 📋38445441Melittin as an Activator of the Autophagy and Unfolded Protein Response Pathways in Colorectal HCT116 Cell Line
Blackcurrant 📋36900589Blackcurrant Alleviates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice
Carotenoids 📋38134087Association between carotenoid intake and metabolic dysfunction-associated fatty liver disease among US adults: A cross-sectional study
Graviola 📋38075540In vitro Evaluation of Cytotoxic Effects of Methanolic Leaf Extracts of Annona muricata on Oral Squamous Cell Carcinoma-15 Cell Lines and its Effect On Expression of Bcl 2-associated X protein, B-cell C/Lymphoma 2 and p53 Genes
Icaritin 📋 38431053Icaritin activates p53 and inhibits aerobic glycolysis in liver cancer cells
L-Arginine 📋37739730Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study
Ollive Leaf extract 📋38467548Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy
Pectin 📋36615814Pectin in Metabolic Liver Disease
Pu-erh Tea 📋36592713Pu-erh tea alleviated colitis-mediated brain dysfunction by promoting butyric acid production
Shiitake Mushrooms 📋38257149Hepatoprotection of a Standardized Extract of Cultured Lentinula edodes Mycelia against Liver Injury Induced by Ischemia-Reperfusion and Partial Hepatectomy
Stinging Nettle 📋38623153Effect of vitamin D3 and a stinging nettle extract on the gastric tissue of rats administered with trinitrobenzene sulfonic acid
Aloin 📋 38038700Aloin Attenuates Oxidative Stress, Inflammation, and CCl4-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling
Asiatic Acid 📋 37375849Asiatic Acid Inhibits Nasopharyngeal Carcinoma Cell Viability and Migration via Suppressing STAT3 and Claudin-1
Betulinic Acid 📋 38261922Betulinic acid arrests cell cycle at G2/M phase by up-regulating metallothionein 1G inhibiting proliferation of colon cancer cells
Chlorella 📋38704764Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
Myricetin 📋 38483540Myricetin Induces Ferroptosis and Inhibits Gastric Cancer Progression by Targeting NOX4
Myrrh 📋38044939Myrrh protects against IL-13-induced epithelial barrier breakdown in HT-29/B6 cells
Poria Mushrooms 📋 38731645Poria cocos Attenuated DSS-Induced Ulcerative Colitis via NF-κB Signaling Pathway and Regulating Gut Microbiota
Rapamycin 📋 38548510Beneficial Effect of Rapamycin on Liver Fibrosis in a Mouse Model (C57bl/6 Mouse)
Retinoic Acid 📋 38239861Potential antitumour effect of all-trans retinoic acid on regorafenib-treated human colon cancer cell lines
Tangeretin 📋 38022093Tangeretin's Anti-apoptotic Signaling Mechanisms in Oral Cancer Cells: In Vitro Anti-cancer Activity
Ursolic Acid 📋38623614Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against non-alcoholic fatty liver disease
Vitamin B6 📋38698325Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway
Beta-Cryptoxanthin 📋 37049698Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes
Bilberry 📋35889832Protective Effect of Bilberry Anthocyanin Extracts on Dextran Sulfate Sodium-Induced Intestinal Damage in Drosophila melanogaster
Cocoa 📋37836487Dark Chocolate Intake Positively Modulates Gut Permeability in Elite Football Athletes: A Randomized Controlled Study
L-Theanine 📋38611425The Protective Effects of L-Theanine against Epigallocatechin Gallate-Induced Acute Liver Injury in Mice
L-Tryptophan 📋38613060A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients
Magnolol 📋 38660717Magnolol promotes the autophagy of esophageal carcinoma cells by upregulating HACE1 gene expression
Phloretin 📋 37744933Metagenomic signatures reveal the key role of phloretin in amelioration of gut dysbiosis attributed to metabolic dysfunction-associated fatty liver disease by time-dependent modulation of gut microbiome
Vitamin B9 📋37327296Effects of folic acid supplementation on chronic atrophic gastritis based on MTHFR C677T polymorphism
Acacetin 📋 38571642Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification
Acetyl-L-Carnitine 📋38369215The intestinal microbial metabolite acetyl l-carnitine improves gut inflammation and immune homeostasis via CADM2
BCAA 📋37836474Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease
Calycosin 📋 37506138Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF-κB pathway: An in vitro study
D-Mannose 📋38529272Mannose enhances intestinal immune barrier function and dextran sulfate sodium salt-induced colitis in mice by regulating intestinal microbiota
DHEA 📋37669399Anorexia nervosa and adrenal hormones: a systematic review and meta-analysis
Escin 📋36905866Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy
Formononetin 📋 38185065Formononetin promotes fatty acid β-oxidation to treat non-alcoholic steatohepatitis through SIRT1/PGC-1α/PPARα pathway
Guava 📋 36134391Guava Leaf Extract Suppresses Fructose Mediated Non-Alcoholic Fatty Liver Disease in Growing Rats
Roselle 📋38376437Antioxidant and Antineoplastic Activities of Hibiscus sabdariffa Linn. Petal Extracts against Oral Squamous Cell Carcinoma Cell Line
Royal Jelly 📋38337678Exploring the Therapeutic Potential of Royal Jelly in Metabolic Disorders and Gastrointestinal Diseases
Scutellarin 📋 38622131Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression
Bergamot 📋37820919Bergamot polysaccharides relieve DSS-induced ulcerative colitis via regulating the gut microbiota and metabolites
Calcium 📋38456354Implication of calcium supplementations in health and diseases with special focus on colorectal cancer
Camellia 📋 35178105Camelina sativa Oil Treatment Alleviates Castor Oil-Induced Diarrhea in ICR Mice by Regulating Intestinal Flora Composition
Dioscin 📋 38085503Dioscin Impedes Proliferation, Metastasis and Enhances Autophagy of Gastric Cancer Cells via Regulating the USP8/TGM2 Pathway
Glycyrrhetinic Acid 📋 38244730Ursodeoxycholic acid and 18β-glycyrrhetinic acid alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells
Lingonberry 📋 35802745Inhibitory effect of lingonberry extract on HepG2 cell proliferation, apoptosis, migration, and invasion
Milk Thistle 📋36788749Combinatorial treatment with Silybum marianum essential oil enhances the therapeutic efficacy of a 5-fluorouracil base therapy for hepatocellular carcinoma
Oats 📋 38140314Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis
Sea Buckthorn 📋37833431Hippophae rhamnoides reverses decreased CYP2D6 expression in rats with BCG-induced liver injury
St. Johns Wort 📋37950737Cytotoxic and anti-metastatic effects of Hypericum perforatum olive oil extract in colorectal cancer cells and human bone marrow derived stem cells
Strawberry 📋36901426Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism
Zingerone 📋 37766888Zingerone attenuates intestinal injury and colitis caused by a high-fat diet through Nrf2 signaling regulation
Antioxidants 📋 38673974Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease
Barberry 📋38732003Berberis vulgaris L. Root Extract as a Multi-Target Chemopreventive Agent against Colon Cancer Causing Apoptosis in Human Colon Adenocarcinoma Cell Lines
Broccoli 📋 38458274The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders
Crocetin 📋 35094239Crocetin alleviates the caerulein-induced apoptosis and inflammation in AR42J cells by activating SIRT1 via NF-κB
Cryptotanshinone 📋 37435898Cryptotanshinone ameliorates hemorrhagic shock-induced liver injury via activating the Nrf2 signaling pathway
Daidzein 📋37759583Protective Effect of Daidzein against Diethylnitrosamine/Carbon Tetrachloride-Induced Hepatocellular Carcinoma in Male Rats
Diosmetin 📋 37796396Diosmetin induces apoptosis and protective autophagy in human gastric cancer HGC-27 cells via the PI3K/Akt/FoxO1 and MAPK/JNK pathways
Folate 📋37733056Correlation of Nonalcoholic Fatty Liver Disease with Dietary Folate and Serum Folate in U.S. Adults: Cross-Sectional Analyses from National Health and Nutrition Examination Survey 2009-2018
Kudzu Root 📋36384052Induction of autophagy via the PI3K/Akt/mTOR signaling pathway by Pueraria flavonoids improves non-alcoholic fatty liver disease in obese mice
Limonin 📋 38455137Limonin inhibits the stemness of cancer stem-like cells derived from colorectal carcinoma cells potentially via blocking STAT3 signaling
Paeonol 📋 38574779Paeonol attenuates nonalcoholic steatohepatitis by regulating intestinal flora and AhR/NLRP3/Caspase-1 metabolic pathway
Perilla 📋 37834377Therapeutic Effects of Perilla Phenols in Oral Squamous Cell Carcinoma
Vitamin B12 📋37275922Protective role of vitamin B12 on acetic acid induced colitis in rats
Vitamin B2 📋38597225Riboflavin ameliorates intestinal inflammation via immune modulation and alterations of gut microbiota homeostasis in DSS-colitis C57BL/6 mice
Aged Garlic 📋34136174Synergistic effects of black ginseng and aged garlic extracts for the amelioration of nonalcoholic fatty liver disease (NAFLD) in mice
Cinnamon Essential Oil 📋38666995Efficacy and Synergistic Potential of Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum L. Merr. & Perry) Essential Oils to Control Food-Borne Pathogens in Fresh-Cut Fruits
Conjugated Linoleic Acid 📋36132168Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells
Echinacea 📋38732552Echinacea purpurea Polysaccharide Ameliorates Dextran Sulfate Sodium-Induced Colitis by Restoring the Intestinal Microbiota and Inhibiting the TLR4-NF-κB Axis
Essential Oils 📋 37299569The Potential of Natural Oils to Improve Inflammatory Bowel Disease
Fruits 📋 38019753Causal association between dietary factors and esophageal diseases: A Mendelian randomization study
Ginkgolides 📋 36375817Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora
Icariin 📋 38621977[Study on mechanism of icariin-induced ferroptosis in HepG2 hepatoma carcinoma cells through PPARG/FABP4/GPX4 pathway]
Isorhamnetin 📋 38612598Isorhamnetin Alleviates Mitochondrial Injury in Severe Acute Pancreatitis via Modulation of KDM5B/HtrA2 Signaling Pathway
MSM 📋38099147Methylsulfonylmethane ameliorates metabolic-associated fatty liver disease by restoring autophagy flux via AMPK/mTOR/ULK1 signaling pathway
Orange 📋 32570775Flavonoid-Rich Orange Juice Intake and Altered Gut Microbiome in Young Adults with Depressive Symptom: A Randomized Controlled Study
Parthenolide 📋 38703207Parthenolide alleviates indomethacin-induced gastric ulcer in rats via antioxidant, anti-inflammatory, and antiapoptotic activities
Piperlongumine 📋 38452870Anti-cancer agent piperlongumine is an inhibitor of transient receptor potential melastatin 7 channel in oral squamous cell carcinoma
Rhubarb 📋 38579425Mid-infrared spectroscopic identification of the right-baked rhubarb for ulcerative colitis therapy
Rosemary 📋38481883Anticancer Effects of Rosmarinus officinalis Leaf Extract on KB Cell Lines
Sesamin 📋 38679210Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo
Spikenard 📋35561851Terpenoids from Nardostachys jatamansi and their cytotoxic activity against human pancreatic cancer cell lines
Theaflavins 📋 37549726Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling
Vitamins 📋 37964614Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias
Avocado 📋38407926Cytotoxic and Antitumoral Effects of Methanolic Extracts of Avocado Fruit Mesocarp in Colorectal Cancer Cell Line HT29
DIM 📋377932043, 3'-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing "glycolysis-lactate-STAT3″ and TIP60 signals-mediated Treg differentiation
Galangal 📋37664921Exploring the Underlying Mechanism of Alpinia officinarum Hance Ameliorating Diabetic Gastroparesis through Combining Network Pharmacology, Molecular Docking, and in Vivo Experimental Verification
Geraniol 📋 36849063Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Geraniol alleviates acute liver failure
Krill Oil 📋38672464Krill Oil and Its Bioactive Components as a Potential Therapy for Inflammatory Bowel Disease: Insights from In Vivo and In Vitro Studies
Magnolia 📋37393026Identification of the therapeutic effect and molecular mechanism of Coptis chinensis Franch. and Magnolia officinalis var. biloba on chronic gastritis
Quinoa 📋 38226896A quinoa peptide protects impaired mucus barriers in colitis mice by inhibiting NF-κB-TRPV1 signaling and regulating the gut microbiota
Spermidine 📋 38695904Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine
Tomato 📋 38398886Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study
Yogurt 📋 38628190Probiotic yogurt regulates gut microbiota homeostasis and alleviates hepatic steatosis and liver injury induced by high-fat diet in golden hamsters
Artichoke 📋37891925Evaluation of the Protective and Regenerative Properties of Commercially Available Artichoke Leaf Powder Extract on Plasma and Liver Oxidative Stress Parameters
Balloon Flower 📋38542804Platycodi Radix Extract Prevents Hepatic Steatosis by Enhancing Bile Acid Synthesis in a High-Fat Diet-Induced Fatty Liver Mouse Model
Beta-Lapachone 📋 38218311β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway
Bitter Melon 📋35527657Momordica charantia polysaccharides alleviate diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and barrier via NF-κB pathway
Black Tea Polyphenols 📋 36008552Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway
Cyanidin 📋 36552590Cyanidin Alleviated CCl4-Induced Acute Liver Injury by Regulating the Nrf2 and NF-κB Signaling Pathways
Diallyl Trisulfide 📋 37964870Prediction of the mechanism for the combination of diallyl trisulfide and cisplatin against gastric cancer: a network pharmacology study and pharmacological evaluation
Fenugreek 📋37336337Isolation of alkaloidal and glycosidal fractions from leaves of Trigonella foenum-graecum L. cv. Desi indigenous to Pakistan for antiprostaglandin evaluation as substitute of nonsteroidal anti-inflammatory drugs
Fig 📋 35427822Autophagy is involved in Ficus carica fruit extract-induced anti-tumor effects on pancreatic cancer
Ginkgolic Acid 📋 38387271Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect
Gotu Kola 📋37576314A herb mixture to ameliorate non-alcoholic fatty liver in rats fed a high-fat diet
Kimchi 📋 38367426Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice
L-Citrulline 📋38306371Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion
Lemon Balm 📋38303002Melissa officinalis extract palliates redox imbalance and inflammation associated with hyperthyroidism-induced liver damage by regulating Nrf-2/ Keap-1 gene expression in γ-irradiated rats
Lion's Mane Mushrooms 📋38556226Polysaccharides from an edible mushroom, Hericium erinaceus, alleviate ulcerative colitis in mice by inhibiting the NLRP3 inflammasomes and reestablish intestinal homeostasis
Lutein 📋36770846Lutein Induces Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer AGS Cells via NADPH Oxidase Activation
Lychee 📋 36774343Litchi procyanidins inhibit colon cancer proliferation and metastasis by triggering gut-lung axis immunotherapy
Nimbolide 📋 38561609The Neem Limonoid Nimbolide Modulates Key Components of the DNA Damage Response Signalling in Cellular and Animal Models of Oral Squamous Cell Carcinoma
Nuciferine 📋 37833979Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway
Oleanolic Acid 📋 38387275Oleanolic acid inhibits hypoxic tumor-derived exosomes-induced premetastatic niche formation in hepatocellular carcinoma by targeting ERK1/2-NFκB signaling
Oolong Tea 📋 38268839Aged oolong tea alleviates dextran sulfate sodium-induced colitis in mice by modulating the gut microbiota and its metabolites
Proanthocyanidins 📋 37719964Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway
PUFA 📋 38388563Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth
Safranal 📋 35740022Molecular Mechanisms behind Safranal's Toxicity to HepG2 Cells from Dual Omics
Vitexin 📋 37676484Regulation of gut microbiota and alleviation of DSS-induced colitis by vitexin
Whey Protein 📋38573884Whey protein supplementation reduced the liver damage scores of rats fed with a high fat-high fructose diet
Ashwagandha 📋38674831In Vitro Inhibition of Colorectal Cancer Gene Targets by Withania somnifera L. Methanolic Extracts: A Focus on Specific Genome Regulation
Bitter Orange 📋36425596Bioactivity guided isolation and identification of phenolic compounds from Citrus aurantium L. with anti-colorectal cancer cells activity by UHPLC-Q-TOF/MS
Blackberry 📋 38675162Anti- Helicobacter pylori Biofilm Extracts from Rubus idaeus and Rubus occidentalis
Chrysanthemum 📋37099836Effects and mechanism of action of Chrysanthemum morifolium (Jinsi Huangju) on hyperlipidemia and non-alcoholic fatty liver disease
Fennel 📋35802574The effect of a fennel seed extract on the STAT signaling and intestinal barrier function
Haritaki 📋38152693Ethyl acetate extract of Terminalia chebula alleviates DSS-induced ulcerative colitis in C57BL/6 mice
Linoleic Acid 📋36263307Association between dietary intake of fatty acids and colorectal cancer, a case-control study
Myrtle 📋35056895Beneficial Effects of Laurel ( Laurus nobilis L.) and Myrtle ( Myrtus communis L.) Extract on Rat Health
Persimmon 📋 35766964Persimmon Water Extract Suppresses Hepatic Lipotoxicity by Regulating Lipid Metabolites
Phosphatidylcholine 📋38262589Oral supplementation of phosphatidylcholine attenuates the onset of a diet-induced metabolic dysfunction-associated steatohepatitis in female C57BL/6J mice
Plum 📋 35971232Prune juice containing sorbitol, pectin, and polyphenol ameliorates subjective complaints and hard feces while normalizing stool in chronic constipation: A randomized placebo-controlled trial
Pomegranate Seed extract 📋 38065332Pomegranate Seed Oil Mitigates Liver and Kidney Damage in an Experimental Colitis Model: Modulation of NF-κB Activation and Apoptosis
Sage 📋36034079Salvia officinalis leaf extracts protect against acute colitis in rats
Sesamol 📋 37976698Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage
Sweet Potato 📋 36505243Sweet potato extract alleviates high-fat-diet-induced obesity in C57BL/6J mice, but not by inhibiting pancreatic lipases
Tea Polyphenols 📋 38307369Study on the relationship between tea polyphenols alleviating osteoporosis and the changes of microorganism-metabolite-intestinal barrier
Theabrownins 📋 38642504Theabrownin from Qingzhuan tea prevents high-fat diet-induced MASLD via regulating intestinal microbiota
Biochanin A 📋 38648921Biochanin a ameliorates DSS-induced ulcerative colitis by improving colonic barrier function and protects against the development of spontaneous colitis in the Muc2 deficient mice
Buckwheat 📋 36615659Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health
Cardamonin 📋 37302524A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases
Carnosol 📋 37386230Downregulation of SODD mediates carnosol-induced reduction in cell proliferation in esophageal adenocarcinoma cells
Carrot 📋 37764365Effect of Extraction Methods on the Antioxidant Potential and Cytotoxicity of the Combined Ethanolic Extracts of Daucus carota L., Beta vulgaris L., Phyllanthus emblica L. and Lycopersicon esculentum against Gastric Adenocarcinoma Cells
Chaga Mushrooms 📋38720012Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism
Cherry 📋 37266135Phytochemical screening of Prunus avium for its antioxidative and anti-mutagenic potential against DMBA-induced hepatocarcinogenesis
Choline 📋38711145Dietary choline intake and health outcomes in U.S. adults: exploring the impact on cardiovascular disease, cancer prevalence, and all-cause mortality
Coumaric acid 📋 37183931The protective effect of p-Coumaric acid on hepatic injury caused by particulate matter in the rat and determining the role of long noncoding RNAs MEG3 and HOTAIR
Date 📋 36386915Potential bioactivity of Phoenix dactylifera fruits, leaves, and seeds against prostate and pancreatic cancer cells
Fennel Essential Oil 📋34725578Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb®) in Relieving Constipation
Ganoderic Acid 📋 38322557Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning
Genipin 📋 38175425Genipin inhibits proliferation of gastric cancer cells by inducing ferroptosis: an integrated study of network pharmacology and bioinformatics study
Hyaluronic Acid 📋37920632Hyaluronic Acid: Exploring Its Versatile Applications in Dentistry
Hyperoside 📋 37923159Hyperoside attenuates carbon tetrachloride-induced hepatic fibrosis via the poly(ADP-ribose)polymerase-1-high mobility group protein 1 pathway
Mango 📋 38682277Colon-available mango (poly)phenols exhibit mitigating effects on the intestinal barrier function in human intestinal cell monolayers under inflammatory conditions
Mastic 📋37147480Mastic (Pistacia lentiscus) gum and oral health: a state-of-the-art review of the literature
Neem 📋 38585261The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study
Neferine 📋 37031639Neferine ameliorates nonalcoholic steatohepatitis through regulating AMPK pathway
Olive Polyphenols 📋 38528541Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis
Postbiotics 📋 38596883Postbiotic Administration Ameliorates Colitis and Inflammation in Rats Possibly through Gut Microbiota Modulation
Red Yeast Rice 📋37358849Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality
SAMe 📋37634598Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice
Syringic Acid 📋 38644776Syringic acid guards against indomethacin-induced gastric ulcer by alleviating inflammation, oxidative stress and apoptosis
Tannic Acid 📋37642057Triggering of Endoplasmic Reticulum Stress by Tannic Acid Inhibits the Proliferation and Migration of Colorectal Cancer Cells
Vitamin K2 📋38321064Vitamin K2 protects mice against non-alcoholic fatty liver disease induced by high-fat diet
Arjuna 📋37850546Optimizing the extraction of polyphenols from the bark of Terminalia arjuna and an in-silico investigation on its activity in colorectal cancer
Asafoetida 📋38138502Antitumor and Phytochemical Properties of Ferula assa-foetida L. Oleo-Gum-Resin against HT-29 Colorectal Cancer Cells In Vitro and in a Xenograft Mouse Model
Asiaticoside 📋 38384110Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology
Asparagus 📋 36596190Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria
Astragalin 📋 37088763[Effects of Astragalin on apoptosis of undifferentiated gastric cancer cells]
Beets 📋37764365Effect of Extraction Methods on the Antioxidant Potential and Cytotoxicity of the Combined Ethanolic Extracts of Daucus carota L., Beta vulgaris L., Phyllanthus emblica L. and Lycopersicon esculentum against Gastric Adenocarcinoma Cells
Berries 📋 38067418In Vitro Inhibitory Potential of Different Anthocyanin-Rich Berry Extracts in Murine CT26 Colon Cancer Cells
Bilobalide 📋 38125341Bilobalide attenuates lipopolysaccharide‑induced HepG2 cell injury by inhibiting TLR4‑NF‑κB signaling via the PI3K/Akt pathway
Black Pepper 📋37765133Piper nigrum Extract Inhibits the Growth of Human Colorectal Cancer HT-29 Cells by Inducing p53-Mediated Apoptosis
Boric Acid 📋37770673Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms
Caffeic Acid 📋35269912Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates
CAPE 📋 38379263Caffeic acid phenethyl ester mediates apoptosis in serum-starved HT29 colon cancer cells through modulation of heat shock proteins and MAPK pathways
Cardamom 📋37779590Protective effects of cardamom aqueous extract against tamoxifen-induced pancreatic injury in female rats
Citrus Fruits 📋 36370925Citrus peel ameliorates mucus barrier damage in HFD-fed mice
Cornus 📋 37716032Cornuside improves murine autoimmune hepatitis through inhibition of inflammatory responses
Delphinidin 📋 36179123Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells
Eleuthero 📋37467688Syringin alleviates hepatic fibrosis by enhancing autophagic flux and attenuating ER stress-TRIB3/SMAD3 in diabetic mice
Fo-Ti Root 📋38284886Prepared radix polygoni multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Isoquercitrin 📋 38084034Isoquercitrin alleviates lipopolysaccharide-induced intestinal mucosal barrier damage in mice by regulating TLR4/MyD88/NF-κB signaling pathway and intestinal flora
Jasmine 📋 36558518Cold-Brewed Jasmine Tea Attenuates High-Fat Diet-Induced Obesity and Gut Microbial Dysbiosis
Kombucha 📋38149073Evaluation of the Efficacy of Kombucha-Based Drink Enriched with Inulin and Vitamins for the Management of Constipation-Predominant Irritable Bowel Syndrome in Females: A Randomized Pilot Study
L-Carnosine 📋38348714Quantitative proteomics study of carnosine effect in an animal model of Western diet-induced nonalcoholic fatty liver disease
Lavender Essential Oil 📋36910997Efficacy of Aromatherapy for Night Crying in Infants with Infantile Colic: A Double-Blind Randomized Controlled Trial
Lotus 📋 38526570Lotus Leaf Extract Alleviates Lipopolysaccharide-Induced Intestinal Injury in Mice by Regulating Oxidative Stress and Inflammation
Malvidin 📋 36562464Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium
Osmanthus 📋38380575Ethyl acetate fraction of Osmanthus fragrans var. aurantiacus and its triterpenoids suppress proliferation and survival of colorectal cancer cells by inhibiting NF-κB and COX2
Peanut 📋 36187387Inverse relations between Helicobacter pylori infection and risk of esophageal precancerous lesions in drinkers and peanut consumption
Quercitrin 📋 35337161Quercetin and Quercitrin from Agrimonia pilosa Ledeb Inhibit the Migration and Invasion of Colon Cancer Cells through the JNK Signaling Pathway
Seaweeds 📋 37201636Seaweed polysaccharides treatment alleviates injury of inflammatory responses and gut barrier in LPS-induced mice
Soy 📋36777798Association between soy products, fruits, vegetables, and dairy products and gastric cancer risk in Helicobacter pylori-infected subjects: a case-control study in Korea
Stigmasterol 📋 38678948Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma
Vegetables 📋 38374605Effect of Vegetable Consumption on Risk of Gastric Cancer: A Systematic Review and Multi-level Meta-analysis of Prospective Studies
Wine 📋 37712265[Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis]
Zeaxanthin 📋36690321Zeaxanthin prevents ferroptosis by promoting mitochondrial function and inhibiting the p53 pathway in free fatty acid-induced HepG2 cells
Anethole 📋 37242484Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways
Anise 📋38103135Anise (Pimpinella anisum L.) attenuates azoxymethane-induced colorectal cancer by antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats
Anthocyanidins 📋 36516693Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK- and NF-kB dependent manner: Results from the ATTACH-study a randomized, controlled, crossover trial in healthy subjects
Apricot Kernels 📋34146630Phytochemical characterization and biological activity of apricot kernels' extract in yeast-cell based tests and hepatocellular and colorectal carcinoma cell lines
Bay Leaf 📋 38628202Anti-inflammatory effects of bay laurel (Laurus nobilis L.) towards the gut microbiome in dextran sodium sulfate induced colitis animal models
Chondroitin 📋37870229Effect of Oral Chondroitin Sulfate Supplementation on Acute Brain Injury in a Murine Necrotizing Enterocolitis Model
Citral 📋 38132361Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries
Clove 📋 37608671Therapeutic Potential of Syzygium aromaticum in Gut Dysbiosis via TMAO Associated Diabetic Cardiomyopathy
Clove Essential Oil 📋 38666995Efficacy and Synergistic Potential of Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum L. Merr. & Perry) Essential Oils to Control Food-Borne Pathogens in Fresh-Cut Fruits
Coconut Oil 📋 37905950Virgin Coconut Oil Alleviates Dextran Sulphate-Induced Inflammatory Bowel Disease and Modulates Inflammation and Immune Response in Mice
Coriander 📋 37518878Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
D-Limonene 📋38540754Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
Diallyl Disulfide 📋 38642008Diallyl disulfide antagonizes DJ-1 mediated proliferation, epithelial-mesenchymal transition, and chemoresistance in gastric cancer cells
Egg 📋 38037542Egg Yolk Lipids Alleviated Dextran Sulfate Sodium-Induced Colitis by Inhibiting NLRP3 Inflammasome and Regulating Gut Microbiota
Fish 📋 37889850Associations of Fish and Fish Oil Consumption With Incident Inflammatory Bowel Disease: A Population-Based Prospective Cohort Study
Ginger Essential Oil 📋 37210385Ginger essential oil and citral ameliorates atherosclerosis in ApoE-/- mice by modulating trimethylamine-N-oxide and gut microbiota
Jujube 📋 38600887Polyphenol Extracts from Ziziphus jujuba Mill. "Junzao" Attenuates Ulcerative Colitis by Inhibiting the NLRP3 and MAPKs Signaling Pathways and Regulating Gut Microbiota Homeostasis in Mice
Lemon 📋 38204757Citrus limon (L.) Osbeck Fruit Peel Extract Attenuates Carbon Tetrachloride-Induced Hepatocarcinogenesis in Sprague-Dawley Rats
Linalool 📋 38240782Effects of linalool on postoperative peritoneal adhesions in rats
Marjoram 📋 38420828Calcium Channel Inhibitory Effect of Marjoram ( Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity
Modified Citrus Pectin 📋34789268MCP mediated active targeting calcium phosphate hybrid nanoparticles for the treatment of orthotopic drug-resistant colon cancer
Morin 📋 37802874[Morin induces autophagy and apoptosis in hepatocellular carcinoma cells through Akt/mTOR/STAT3 pathway]
Morusin 📋 38432611Morusin suppresses the stemness characteristics of gastric cancer cells induced by hypoxic microenvironment through inhibition of HIF-1α accumulation
Mushrooms 📋 38154526Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-β1/Smads pathways
Noni 📋 38144717Constituent analysis, laxative activity, and toxicological evaluation of methanol extract of noni fruit ( Morinda citrifolia L., Rubiaceae)
Onion 📋37659760Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories
Pistachio 📋32801830The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis
Protein 📋37407836Associations of intakes of total protein, protein from dairy sources, and dietary calcium with risks of colorectal, breast, and prostate cancer: a prospective analysis in UK Biobank
Rehmannia 📋36908905Oligosaccharides isolated from Rehmannia glutinosa protect LPS-induced intestinal inflammation and barrier injury in mice
Thyme 📋38271407Anti H. pylori, anti-secretory and gastroprotective effects of Thymus vulgaris on ethanol-induced gastric ulcer in Sprague Dawley rats
Tribulus Terrestris 📋38309487In-depth investigation of the therapeutic effect of Tribulus terrestris L. on type 2 diabetes based on intestinal microbiota and feces metabolomics
Barley 📋36495148Barley Grass Juice Attenuates Hydrodynamic Transfection-Induced HCC Initiation in Mice
Basil 📋38058645Ameliorating effects of Acacia arabica and Ocimum basilicum on acetic acid-induced ulcerative colitis model through mitigation of inflammation and oxidative stress
Cabbage 📋 38337674Anti-Inflammatory Effect of Chestnut Honey and Cabbage Mixtures Alleviates Gastric Mucosal Damage
Caraway Essential Oil 📋 32711288Menthacarin attenuates experimental colitis
Catalpol 📋 37979473Catapol attenuates the aseptic inflammatory response to hepatic I/R injury in vivo and in vitro by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway via the microRNA-410-3p
Chicory 📋38507851Phenolic acids from Chicory roots ameliorate dextran sulfate sodium-induced colitis in mice by targeting TRP signaling pathways and the gut microbiota
Coconut 📋 38278200Coconut water induces clinical remission in mild to moderate ulcerative colitis: double-blind placebo controlled trial
Fish Collagen 📋37367668Fish-Derived Protein Hydrolysates Increase Insulin Sensitivity and Alter Intestinal Microbiome in High-Fat-Induced Obese Mice
Garlic Oil 📋 35959265Garlic oil alleviates high triglyceride levels in alcohol-exposed rats by inhibiting liver oxidative stress and regulating the intestinal barrier and intestinal flora
Geraniin 📋 38530797Geraniin Alleviates Inflammation in Caco-2 Cells and Dextran Sulfate Sodium-Induced Colitis Mice by Targeting IL-1β
Ginkgetin 📋 38217097Ginkgetin exhibits antifibrotic effects by inducing hepatic stellate cell apoptosis via STAT1 activation
Glabridin 📋 37714449Glabridin ameliorates intracellular events caused by palmitic acid and alcohol in mouse hepatocytes and fast food diet and alcohol -induced steatohepatitis and fibrosis in C57BL/6J mice model
Glucosamine 📋37836761Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism
Grapefruit extract 📋35043844Explore the antiproliferative phytocompounds from ethanolic extracts of Citrus paradisi against liver cancer cell line by chemical analysis using TLC and FT-IR spectroscopy
Guggulsterone 📋 36635928Guggulsterone promotes nasopharyngeal carcinoma cells exosomal circFIP1L1 to mediate miR-125a-5p/VEGFA affecting tumor angiogenesis
Honeysuckle 📋 38307354Study on the ameliorative effect of honeysuckle on DSS-induced ulcerative colitis in mice
Irisin 📋 38671861The Role of the Myokine Irisin in the Protection and Carcinogenesis of the Gastrointestinal Tract
Knotweed 📋36683716In vivo recognition of bioactive substances of Polygonum multiflorum for protecting mitochondria against metabolic dysfunction-associated fatty liver disease
Lemon Essential Oil 📋38132361Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries
Loquat 📋38608471Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis
Milk 📋 38370079Consumption of dairy products and odds of ulcerative colitis: An Iranian case-control study
Nutmeg 📋35565666Myristica fragrans Extract Regulates Gut Microbes and Metabolites to Attenuate Hepatic Inflammation and Lipid Metabolism Disorders via the AhR-FAS and NF-κB Signaling Pathways in Mice with Non-Alcoholic Fatty Liver Disease
Okra 📋 38004214Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated Cancer
Oleic Acid 📋 37253404Oleic acid improves hepatic lipotoxicity injury by alleviating autophagy dysfunction
Soy Isoflavones 📋37375574The Role of Choline, Soy Isoflavones, and Probiotics as Adjuvant Treatments in the Prevention and Management of NAFLD in Postmenopausal Women
Valerian Root 📋35863616Antidiarrheal activity of the extracts of Valeriana jatamansi Jones on castor oil-induced diarrhea mouse by regulating multiple signal pathways
White Tea 📋 38628196Investigation of the effects of white tea on liver fibrosis: An experimental animal model
Almond 📋 34057922Almond protects the liver in coronary artery disease: A randomized controlled clinical trial
Banana 📋 36692306Role of cooked green banana in home management of acute diarrhea in under-5 children
Basil Essential Oil 📋32641615Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model With Special Reference to Gut Microbiota
Bee Pollen 📋37330827Integrated microbiomic and metabolomic analyses reveal the mechanisms by which bee pollen and royal jelly lipid extracts ameliorate colitis in mice
Bile Salts 📋 38680685The role of bile acids in human aging
Chia Seeds 📋 37689868Chia (Salvia hispanica L.) flour modulates the intestinal microbiota in Wistar rats fed a high-fat and high-fructose diet
Citicoline 📋37291355Valuable effects of lactobacillus and citicoline on steatohepatitis: role of Nrf2/HO-1 and gut microbiota
Colostrum 📋38409162Therapeutics effects of bovine colostrum applications on gastrointestinal diseases: a systematic review
Copper 📋38579045The association between intakes of dietary trace minerals and gallstone disease: A cross-sectional study from National Health and Nutrition Examination Survey 2017 to 2018
Dairy 📋 37650016Influence of dairy products consumption on oral cancer risk: A meta-analysis
Echinacoside 📋 38461536Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma
Elderberry 📋37895164Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo
Eucalyptus 📋35284740Cheminformatics Application in the Phytochemical and Biological Study of Eucalyptus globulus L. Bark as a Potential Hepatoprotective Drug
Eucommia 📋36982954Eucommia Polysaccharides Ameliorate Aging-Associated Gut Dysbiosis: A Potential Mechanism for Life Extension in Drosophila
Flaxseed Oil 📋37960203Flaxseed Oil ( Linum usitatissimum) Prevents Cognitive and Motor Damage in Rats with Hyperammonemia
Goat Milk 📋 37830350Fermented Goat's Milk Contributes to the Recovery of Iron Deficiency Anemia via Modulation of the Gut Microbiome
Haskap 📋 37764808Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway
Hazelnut 📋 37200761Study of the Apoptotic Impacts of Hazelnut Oil on the Colorectal Cancer Cell Line
Holy Basil 📋34440988An In Vitro Anti-Cancer Activity of Ocimum tenuiflorum Essential Oil by Inducing Apoptosis in Human Gastric Cancer Cell Line
Hypericin 📋 34089613Hypericin-mediated photodynamic therapy enhances gemcitabine induced Capan-2 cell apoptosis via inhibiting NADPH level
L-Methionine 📋38367245l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma
Laminaria 📋36355026Laminaria japonica Peptides Suppress Liver Cancer by Inducing Apoptosis: Possible Signaling Pathways and Mechanism
Ligustilide 📋 35494068Z-Ligustilide Induces c-Myc-Dependent Apoptosis via Activation of ER-Stress Signaling in Hypoxic Oral Cancer Cells
Liquiritigenin 📋 37455324Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K/AKT pathway
Liquiritin 📋 36008890Liquiritin alleviates alpha-naphthylisothiocyanate-induced intrahepatic cholestasis through the Sirt1/FXR/Nrf2 pathway
Lupeol 📋 35486494Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF-κB pathway
Marigold 📋32039173Marigold Supercritical Extract as Potential Co-adjuvant in Pancreatic Cancer: The Energetic Catastrophe Induced via BMP8B Ends Up With Autophagy-Induced Cell Death
Millet 📋 36638159Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake
Minerals 📋 37764853The Effect of Polyphenols, Minerals, Fibers, and Fruits on Irritable Bowel Syndrome: A Systematic Review
Nicotinamide 📋33870623Nicotinamide Protects Against Diet-Induced Body Weight Gain, Increases Energy Expenditure and Induces White Adipose Tissue Beiging
Oregano Essential Oil 📋36903396Savory, Oregano and Thyme Essential Oil Mixture (HerbELICO®) Counteracts Helicobacter pylori
Oyster 📋 36965559Oyster polysaccharides relieve DSS-induced colitis via anti-inflammatory and maintaining the physiological hypoxia
Oyster Mushrooms 📋 36374945Anticancer Properties of Selenium-Enriched Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), in Colon Cancer In Vitro
Papaya 📋38388061Ripe papaya pectins inhibit the proliferation of colon cancer spheroids and the formation of chemically induced aberrant crypts in rats colons
Pau d'Arco 📋28877696Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb.) water extract prevents DSS-induced colitis in mice by up-regulating type II T helper immune responses
Pineapple 📋34946738Pineapple Leaf Phenols Attenuate DSS-Induced Colitis in Mice and Inhibit Inflammatory Damage by Targeting the NF-κB Pathway
Potato 📋 38253109Dietary purple potato supplement attenuates DSS-induced colitis in mice: Impact on mitochondrial function
PQQ 📋34227919Pyrroloquinoline quinone (PQQ) alleviated sepsis-induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression
Prickly Pear 📋 38474715A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of Opuntia ficus- indica Prebiotic Supplementation in Subjects with Gut Dysbiosis
Radish 📋 36501112Hepatoprotective Effects of Radish ( Raphanus sativus L.) on Acetaminophen-Induced Liver Damage via Inhibiting Oxidative Stress and Apoptosis
Rice 📋 36615905Red Rice Bran Extract Alleviates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease and Dyslipidemia in Mice
Sesame 📋37781062Antioxidant activities of thermally treated Sesamum indicum L. leaf extracts and their inhibitory effects against growth and metastatic properties of human colon cancer cells
Soy Protein 📋38075211Feeding soy protein concentrates with low or high isoflavone decreases liver inflammation by reducing lipopolysaccharide translocation
Telmisartan 📋 37831115Telmisartan and candesartan promote browning of white adipose tissue and reverse fatty liver changes in high fat diet fed male albino rats
Thyme Essential Oil 📋 38034947Comparison of the virucidal efficacy of essential oils (cinnamon, clove, and thyme) against hepatitis A virus in suspension and on food-contact surfaces
Trans-Resveratrol 📋 36191991The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma
Vitamin B1 📋37720374Association of vitamin B1 with cardiovascular diseases, all-cause and cardiovascular mortality in US adults
Vitamin K 📋37049518Low Vitamin K and Vitamin D Dietary Intake in Patients with Inflammatory Bowel Diseases
Yam 📋 37545095Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways
Apple Vinegar 📋36564752Effect of apple vinegar on folliculogenesis and ovarian kisspeptin in a high-fat diet-induced nonalcoholic fatty liver disease in rat
Bamboo 📋38334213The alleviative effects comparison of four flavonoids from bamboo leaves on ulcerative colitis in an Alzheimer mouse model
Chicoric Acid 📋 38485738Chicoric Acid Alleviates Colitis via Targeting the Gut Microbiota Accompanied by Maintaining Intestinal Barrier Integrity and Inhibiting Inflammatory Responses
Chitosan 📋37749921Pharmacodynamic study of chitosan in combination with salvianolic acid B in the treatment of CC14 -induced liver fibrosis in mice
Costus 📋37396159Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease
Fermented Foods 📋 38163708The attenuating effect of fermented soymilk on DSS-induced colitis in mice by suppressing immune response and modulating gut microbiota
Gamma-Linolenic Acid 📋38443203The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats
Grapefruit Essential Oil 📋32760938Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis
HMB 📋37739730Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study
Iodine 📋38305374Clinical Efficacy of Different Concentrations of Povidone Iodine in the Management of Peri-Implant Mucositis
Kale 📋 38094924Kale improves bowel movements in constipated women and affects some intestinal microbes and metabolites: a pilot study
L-Lysine 📋37648521L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model
Lauric Acid 📋 38166588Lauric acid attenuates hepato-metabolic complications and molecular alterations in high-fat diet-induced Non-alcoholic Fatty Liver Disease in rats
Lemongrass 📋38399374Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review
Marjoram Essential Oil 📋 35642325GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori
NAD 📋 37371959NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies
Nattokinase 📋36350434Nattokinase enhances the preventive effects of Escherichia coli Nissle 1917 on dextran sulfate sodium-induced colitis in mice
Neroli Essential Oil 📋35087623Transdermal Administration of Volatile Oil from Citrus aurantium- Rhizoma Atractylodis Macrocephalae Alleviates Constipation in Rats by Altering Host Metabolome and Intestinal Microbiota Composition
Nuts 📋 37242277Effect of Nut Consumption on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Omega-6 Fatty Acids 📋35648467Associations of serum n-3 and n-6 polyunsaturated fatty acids with prevalence and incidence of non-alcoholic fatty liver disease
Orange Essential Oil 📋38349052Effects of the protective and therapeutic effect of yogurt enriched with Citrus sinensis essential oil against ibuprofen-induced gastric ulcer in elderly rats
Oregano 📋36284120Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy
Papain 📋37692988Therapeutic effect of bromelain and papain on intestinal injury induced by indomethacin in male rats
Peach 📋 37064951Molecular Mechanism of the Therapeutic Effect of Peach Blossom against Constipation: An Exploratory Study Based on Network Pharmacology Analysis and Molecular Docking Verification
Rose 📋 37797686Evaluation of the flavonol-rich fraction of Rosa damascena in an animal model of liver fibrosis by targeting the expression of fibrotic cytokines, antioxidant/oxidant ratio and collagen cross-linking
Safflower 📋38593703Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function
Sesame Oil 📋 35685535Sesame Oil Ameliorates Alanine Aminotransferase, Aspartate Aminotransferase, and Fatty Liver Grade in Women with Nonalcoholic Fatty Liver Disease Undergoing Low-Calorie Diet: A Randomized Double-Blind Controlled Trial
Spearmint 📋 31174376Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice
Spices 📋 38672692An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer
Star Anise 📋35586683Anisi Stellati Fructus, a Significant Traditional Chinese Medicine (TCM) Herb and Its Bioactivity against Gastric Cancer
Stevia 📋37237936Stevioside Improves Antioxidant Capacity and Intestinal Barrier Function while Attenuating Inflammation and Apoptosis by Regulating the NF-κB/MAPK Pathways in Diquat-Induced Oxidative Stress of IPEC-J2 Cells
Tea Polysaccharides 📋 37876151Amelioration Effects and Regulatory Mechanisms of Different Tea Active Ingredients on DSS-Induced Colitis
Tetrahydrocurcumin 📋 30652650Tetrahydrocurcumin, Curcumin, and 5-Fluorouracil Effects on Human Esophageal Carcinoma Cells
Trehalose 📋 37581638Trehalose-induced SIRT1/AMPK activation regulates SREBP-1c/PPAR-α to alleviate lipid accumulation in aged liver
Vitamin B Complex 📋 38188454Role of N-acetylcysteine and vitamin B complex in improving outcomes of corrosive ingestion
Vitamin B3 📋37836412Association between Dietary Niacin Intake and Nonalcoholic Fatty Liver Disease: NHANES 2003-2018
Vitamin K2 mk-4 📋 26314836Vitamin K Deficiency Leads to Exacerbation of Murine Dextran Sulfate Sodium-Induced Colitis
White Fungus 📋 38244583Tremella fuciformis polysaccharides induce ferroptosis in Epstein-Barr virus-associated gastric cancer by inactivating NRF2/HO-1 signaling
White Mushrooms 📋 38230753Agaricus bisporus polysaccharides ameliorate ulcerative colitis in mice by modulating gut microbiota and its metabolism
Withanolides 📋 38301983Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects
Bergamot Essential Oil 📋35456609Antispasmodic Effect of Bergamot Essential Oil on Rat Isolated Gut Tissues
Beta-Alanine 📋37251265Ellagic acid from whole pomegranate fruit reduces liver injury in a rat model of hepatic cholestasis
Cantaloupe 📋 36934555Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals
Capsanthin 📋 36141454The Utility of Capsicum annuum L. in Internal Medicine and In Dentistry: A Comprehensive Review
Cat's Claw 📋38056537Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats
Celery 📋 38355510Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-κB/NF-κB p65 signaling pathway: insights from in silico and in vivo investigations
Cinnamic Acid 📋 38361356Cinnamic Acid Ameliorates Acetic Acid-induced Inflammatory Response through Inhibition of TLR-4 in Colitis Rat Model
Diallyl Sulfide 📋 37209385Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells
Dill 📋 34704009Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models
Frankincense Essential Oil 📋 37952762Basis with RNA-Seq and WGCNA to explore the effect of Frankincense essential oil on dextran sodium sulfate-induced ulcerative colitis through MAPK/NF-κB signaling
Giloy 📋38280221Traditional uses, hepatoprotective potential, and phytopharmacology of Tinospora cordifolia: a narrative review
Glycine 📋33830211Dietary Supplementation with Glycine Enhances Intestinal Mucosal Integrity and Ameliorates Inflammation in C57BL/6J Mice with High-Fat Diet-Induced Obesity
Iron 📋36742167Iron as a therapeutic target in chronic liver disease
Jackfruit 📋 38338941Polysaccharide from Artocarpus heterophyllus Lam. (Jackfruit) Pulp Ameliorates Dextran Sodium Sulfate-Induced Enteritis in Rats
Lavender 📋35446915Cytotoxic effects of Lavandula angustifolia seed extracts on the viability of Huh-7 and Chang liver cells
Lecithin 📋37676407The Antioxidant and anti-inflammatory Activity of Selenium and Lecithin Combination Against ethanol-induced Gastric Ulcer in mice via Modulating IGF-1/PTEN/Akt/FoxO3a Signaling
Lemongrass Essential Oil 📋37749735Lemongrass Essential Oil Attenuates Perfluorooctane Sulfonate-Induced Jejunal Mucosal Injury in Rat: A Histological, Immunohistochemical, and Biochemical Study
Maca Root 📋37955225The maca protein ameliorates DSS-induced colitis in mice by modulating the gut microbiota and production of SCFAs
Mandarin 📋 35620406Citrus unshiu Peel Attenuates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice due to Modulation of the PI3K/Akt Signaling Pathway and MAPK and NF- κ B
Mucuna Pruriens 📋37395947Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma
Oak Gall 📋38638752Gastroprotective Effect of Quercus infectoria Olivier Galls on Ethanol-Induced Gastritis in Rats
Parsley 📋 37597227[The gastric regenerative effect of consumption of Petroselinum sativum L. (parsley) in rats with gastritis induced by ethanol]
PEA 📋37599675Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism
Peppermint 📋27912953Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial
Pomelo 📋 37419271Aqueous extract of pummelo pulp (Citrus maxima) improves the biochemical profile and reduces the inflammation process in Wistar rats with non-alcoholic fatty liver disease
Prunella Vulgaris 📋38040415Exploring the mechanism of bioactive components of Prunella vulgaris L. in treating hepatocellular carcinoma based on network pharmacology
Rapeseed Oil 📋 36691598Effects of Different Vegetable Oils on the Nonalcoholic Fatty Liver Disease in C57/BL Mice
Rhodiola 📋36096243Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease
Rosemary Essential Oil 📋38459835Rosemary essential oil potentiates the antitumour activity of 5-fluorouracil in human colorectal carcinoma cells
Scutellarein 📋 34445559Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-κB Signaling through PTEN Activation in Hepatocellular Carcinoma
Sea Cucumber 📋 38004208Sea Cucumber Peptides Ameliorate DSS-Induced Ulcerative Colitis: The Role of the Gut Microbiota, the Intestinal Barrier, and Macrophage Polarization
Sesamolin 📋 36630317Sesamolin Attenuates Kidney Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat and High-Fructose Diet-Fed Mice
Shilajit 📋35258780Protective Roles of Shilajit in Modulating Resistin, Adiponectin, and Cytokines in Rats with Non-alcoholic Fatty Liver Disease
Sirtuin Activators 📋 36499440Sirtuins (SIRTs) As a Novel Target in Gastric Cancer
Sodium Bicarbonate 📋36597048Prevention and the treatment of oral mucositis: the efficacy of sodium bicarbonate vs other agents: a systematic review
Star Fuit 📋 31704616Extract of Averrhoacarambola L. (Oxalidaceae) roots ameliorates carbon tetrachloride-induced hepatic fibrosis in rats
Tamarind 📋 37631047Tamarind Seed Polysaccharide Hydrolysate Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis via Regulating the Gut Microbiota
Tea Tree Essential Oil 📋 35155524Tea Tree Oil Terpinen-4-ol Protects Gut Barrier Integrity by Upregulation of Tight Junction Proteins via the ERK1/2-Signaling Pathway
Theobromine 📋33360052Oncopreventive effects of theanine and theobromine on dimethylhydrazine-induced colon cancer model
Turkey Tail Mushrooms 📋 35204289Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect
Vitamin B7 📋38140308Clinical Implications of Dietary Probiotic Supplement (Associated with L-Glutamine and Biotin) in Ulcerative Colitis Patients' Body Composition and Quality of Life
Vitamin B8 📋36963888Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial
Vitamin K1 📋36648304Effect of phylloquinone on indomethacin-induced gastric ulceration in rats: Role of SIRT-1
Yohimbine 📋 37952411Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway
5-HTP 📋35572711Oral Administration of 5-Hydroxytryptophan Restores Gut Microbiota Dysbiosis in a Mouse Model of Depression
Activated Charcoal 📋36132707Dose-dependent Action of Zingiber officinale on Colonic Dysmotility and Ex Vivo Spontaneous Intestinal Contraction Modulation
Aloesin 📋 21277867Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model
Arctiin 📋 38205087Role of Arctiin in Fibrosis and Apoptosis in Experimentally Induced Hepatocellular Carcinoma in Rats
Ashitaba 📋37920601Exploring the underlying mechanisms of Ashitaba in the management of non-alcoholic fatty liver disease by integrating the analysis of transcriptomics and metabolomics
Avocado Oil 📋 36601051Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet
Bacopa Monnieri 📋37951147Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
Black Pepper Essential Oil 📋 36076569Black pepper oil (Piper nigrum L.) mitigates dexamethasone induced pancreatic damage via modulation of oxidative and nitrosative stress
Brussels Sprouts 📋 35057085The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics
Cauliflower 📋 36429638Isothiocyanate-Rich Extracts from Cauliflower ( Brassica oleracea Var. Botrytis) and Radish ( Raphanus sativus) Inhibited Metabolic Activity and Induced ROS in Selected Human HCT116 and HT-29 Colorectal Cancer Cells
Chamomile Essential Oil 📋29681854Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles
Cloudberry 📋 27270323Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice
Coriander Essential Oil 📋24901768Coriandrum sativum L. (Coriander) essential oil: antifungal activity and mode of action on Candida spp., and molecular targets affected in human whole-genome expression
Corn 📋 35761543Black corn (Zea mays L.) soluble extract showed anti-inflammatory effects and improved the intestinal barrier integrity in vivo (Gallus gallus)
Cumin 📋 34328087Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats
Dragon Fruit 📋 37087207Effects of dragon fruit oligosaccharides on immunity, gut microbiome, and their metabolites in healthy adults - A randomized double-blind placebo controlled study
Essential Fatty Acids 📋 35765549Antimicrobial activities of microbial essential fatty acid against foodborne pathogenic bacteria
Eucalyptol 📋 37047133Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation
Eurycomanone 📋 35889271A Quassinoid Diterpenoid Eurycomanone from Eurycoma longifolia Jack Exerts Anti-Cancer Effect through Autophagy Inhibition
Evening Primrose Oil 📋36239291Evening primrose seed extract rich in polyphenols modulates the invasiveness of colon cancer cells by regulating the TYMS expression
Fat 📋 33603741Regulation of Intestinal Inflammation by Dietary Fats
Glutathione 📋36548773Epigallocatechin Gallate and Glutathione Attenuate Aflatoxin B1-Induced Acute Liver Injury in Ducklings via Mitochondria-Mediated Apoptosis and the Nrf2 Signalling Pathway
Grape Seed Oil 📋 38278024The black Vitis vinifera seed oil saponifiable fraction ameliorates hepatocellular carcinoma in vitro and in vivo via modulating apoptosis and ROS/NF-κB signaling
Grapefruit 📋 27166529Anti-inflammatory effects of Citrus sinensis L., Citrus paradisi L. and their combinations
Hemp Oil 📋36734470Integration of transcriptomics and metabonomics revealed the protective effects of hemp seed oil against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice
Horsetail Grass 📋35789647Dose-Dependent Variation in Anticancer Activity of Hexane and Chloroform Extracts of Field Horsetail Plant on Human Hepatocarcinoma Cells
Indian Barberry 📋31888241Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial
L-Histidine 📋37174059Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant-Antioxidant Balance
L-Leucine 📋35245436Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination
L-Proline 📋20693968In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1
Lime 📋 37049726Metabolomic Analysis of Phytochemical Compounds from Ethanolic Extract of Lime ( Citrus aurantifolia) Peel and Its Anti-Cancer Effects against Human Hepatocellular Carcinoma Cells
Mango Leaf 📋 33167456Metabolomic Profiling of Mango ( Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models
Neem Oil 📋31875751Use of Neem Oil and Hypericum perforatum for Treatment of Calcinosis-Related Skin Ulcers in Systemic Sclerosis
Neohesperidin 📋 38226659Orally administered neohesperidin attenuates MPTP-induced neurodegeneration by inhibiting inflammatory responses and regulating intestinal flora in mice
Nootkatone 📋 36671056Nootkatone Supplementation Ameliorates Carbon Tetrachloride-Induced Acute Liver Injury via the Inhibition of Oxidative Stress, NF-κB Pathways, and the Activation of Nrf2/HO-1 Pathway
Oak Acorn 📋35076295Prophylactic Protective Action of Aqueous Extract of Green Oak Acorns on Ethanol-Induced Acute Injury to Rat Gastroduodenal Mucosa
Oak Bark 📋31100197Purpurogallin is a novel mitogen-activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo
Pear 📋 33809380Protective Effect of Pyrus ussuriensis Maxim. Extract against Ethanol-Induced Gastritis in Rats
Pecan 📋 37299553Pecans and Its Polyphenols Prevent Obesity, Hepatic Steatosis and Diabetes by Reducing Dysbiosis, Inflammation, and Increasing Energy Expenditure in Mice Fed a High-Fat Diet
Phytosterols 📋 37756430Phytosterols Protect against Osteoporosis by Regulating Gut Microbiota
Polypodium Leucotomos 📋36686704Polypodium leucotomos targets multiple aspects of oral carcinogenesis and it is a potential antitumor phytotherapy against tongue cancer growth
Potassium 📋38635545Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States
Progesterone 📋36263327Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males
Pumpkin 📋 34805250Sequential Extraction, Characterization, and Analysis of Pumpkin Polysaccharides for Their Hypoglycemic Activities and Effects on Gut Microbiota in Mice
Pumpkin Seed 📋30245714An Appraisal of Pumpkin Seed Extract in 1, 2-Dimethylhydrazine Induced Colon Cancer in Wistar Rats
Pumpkin Seed Oil 📋26405765Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil
Pyridoxal-5-Phosphate 📋24183308Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease
Rosavin 📋 36077546Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death
Rosehip 📋32379993Chemical Characterization of Bioactive Components of Rosa canina Extract and Its Protective Effect on Dextran Sulfate Sodium-Induced Intestinal Bowel Disease in a Mouse Model
Rye 📋 37905980Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in adults
Sage Essential Oil 📋 32531144Antiproliferative Effect and Cell Cycle Alterations Induced by Salvia Officinalis Essential Oil and Its Three Main Components in Human Colon Cancer Cell Lines
Soybean Oil 📋 35276916A Lard and Soybean Oil Mixture Alleviates Low-Fat-High-Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease in Mice
Spearmint Essential Oil 📋34201645Mint Oils: In Vitro Ability to Perform Anti-Inflammatory, Antioxidant, and Antimicrobial Activities and to Enhance Intestinal Barrier Integrity
Sugarcane 📋 30946967A randomized controlled double blinded trial to evaluate efficacy of oral administration of black strap molasses (sugarcane extract) in comparison with polyethylene glycol on pediatric functional constipation
Tangerine 📋 35027935Scutellariae Radix and Citri Reticulatae Pericarpium Mixture Regulate PPAR γ/RXR Signaling in Reflux Esophagitis
Tongkat Ali 📋37511840Anti-Inflammatory, Antinociceptive, Antipyretic, and Gastroprotective Effects of Eurycoma longifolia Jack Ethanolic Extract
Vitamin K2 mk-7 📋 37257737Neuroprotective effect of Vitamin K2 against gut dysbiosis associated cognitive decline
Wheat 📋 37814914Effect of red wheat, aleurone, and testa layers on colon cancer biomarkers, nitrosative stress, and gut microbiome composition in rats
Acemannan 📋 29072072Acemannan and Fructans From Aloe Vera (Aloe Barbadensis Miller) Plants as Novel Prebiotics
Alfalfa 📋 37860685Gastroprotective evaluation of Medicago sativa L. (Fabaceae) on diabetic rats
Almond Oil 📋 35774276Comparison of the Effects of Abdominal Massage and Oral Administration of Sweet Almond Oil on Constipation and Quality of Life among Elderly Individuals: A Single-Blind Clinical Trial
Alpha GPC 📋27861548Targeting Mitochondrial Dysfunction with L-Alpha Glycerylphosphorylcholine
Amaranth 📋 35186332The Role of Pseudocereals in Celiac Disease: Reducing Nutritional Deficiencies to Improve Well-Being and Health
Amino Acids 📋 35786467[Regulation of inflammatory bowel disease by amino acids]
Apricot Oil 📋 30234391Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats
Arachidonic Acid 📋33209199Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells
Azadirachtin 📋 34944759Azadirachtin Attenuates Lipopolysaccharide-Induced ROS Production, DNA Damage, and Apoptosis by Regulating JNK/Akt and AMPK/mTOR-Dependent Pathways in Rin-5F Pancreatic Beta Cells
Beer 📋 36839202Beer and Microbiota: Pathways for a Positive and Healthy Interaction
Black Ginger 📋33503922Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora
Bladderwrack 📋37755091Bioactivity of Fucoidan-Rich Extracts from Fucus vesiculosus against Rotavirus and Foodborne Pathogens
Brazil Nut 📋 27923410Supplementation With Brazil Nuts and Green Tea Extract Regulates Targeted Biomarkers Related to Colorectal Cancer Risk in Humans
Butter 📋 34579147Ghee Butter from Bovine Colostrum Reduces Inflammation in the Mouse Model of Acute Pancreatitis with Potential Involvement of Free Fatty Acid Receptors
Calcium D-Glucarate 📋20393005Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation
Camphor 📋35866389Camphor Seed Kernel Oil Beneficial Effects the Gut Microbiota of the Non-Alcoholic Fatty Liver Disease Mice
Captopril 📋 38542253Renin-Angiotensin Inhibitor, Captopril, Attenuates Growth of Patient-Derived Colorectal Liver Metastasis Organoids
Caraway 📋 35255832A novel duodenal-release formulation of caraway oil and L-menthol is a safe, effective and well tolerated therapy for functional dyspepsia
Cashew 📋 35028183Evaluation of the gastrointestinal anti-motility effect of Anacardium occidentale stem bark extract: A mechanistic study of antidiarrheal activity
Cedarwood Essential Oil 📋32013183The In Vitro Activity of Essential Oils against Helicobacter Pylori Growth and Urease Activity
Chebulinic Acid 📋 35075915Gastric ulcer healing by chebulinic acid solid dispersion-loaded gastroretentive raft systems: preclinical evidence
Cheese 📋 21235114Risk factors for colorectal polyps: findings from a Greek case-control study
Chickpea 📋 37375942Chemopreventive Effect of Cooked Chickpea on Colon Carcinogenesis Evolution in AOM/DSS-Induced Balb/c Mice
Chromium 📋33312555An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice
Collagen 📋 35639457Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study
Cucumber 📋 34832981Cucumis sativus L. Seeds Ameliorate Muscular Spasm-Induced Gastrointestinal and Respiratory Disorders by Simultaneously Inhibiting Calcium Mediated Signaling Pathway
DMAE 📋1646761Improvement of estradiol 17 beta-D-glucuronide cholestasis by intravenous administration of dimethylethanolamine in the rat
Eclipta Alba 📋 35337710Anti-inflammatory effect of wedelolactone on DSS induced colitis in rats: IL-6/STAT3 signaling pathway
Equol 📋37565591Association between equol and non-alcoholic fatty liver disease in Japanese women in their 50s and 60s
Eucalyptus Essential Oil 📋 33660226In Vitro Cytotoxicity and Apoptotic Assay of Eucalyptus globulus Essential Oil in Colon and Liver Cancer Cell Lines
Flavones 📋 37324477Natural flavones from edible and medicinal plants exhibit enormous potential to treat ulcerative colitis
Fluted Gourd 📋 34331468Telfairia occidentalis mitigates dextran sodium sulfate-induced ulcerative colitis in rats via suppression of oxidative stress, lipid peroxidation, and inflammation
GABA 📋38193198Experimental colitis-induced visceral hypersensitivity is attenuated by GABA-treatment in mice
Geranium 📋 32492494Geranium koreanum, a medicinal plant Geranii Herba, ameliorate the gastric mucosal injury in gastritis-induced mice
Helichrysum 📋 24140587Intestinal antispasmodic effects of Helichrysum italicum (Roth) Don ssp. italicum and chemical identification of the active ingredients
Hops 📋35229981Xanthohumol targets the JNK1/2 signaling pathway in apoptosis of human nasopharyngeal carcinoma cells
Horse Chestnut 📋34275854In vitro antioxidant potential and antiproliferative activity of Aesculus indica seed extract against hepatocellular carcinoma cell line
Hyssop 📋31694395Gastroprotective effect of Hyssopus officinalis L. leaves via reduction of oxidative stress in indomethacin-induced gastric ulcer in experimental rats
Isoflavones 📋32548137Isoflavones and inflammatory bowel disease
L-Alanine 📋35698613Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis
L-Tyrosine 📋37490119Dietary antioxidant quercetin overcomes the acquired resistance of Sorafenib in Sorafenib-resistant hepatocellular carcinoma cells through epidermal growth factor receptor signaling inactivation
Lemon Balm Essential Oil 📋32041100Methylcellulose Hydrogel with Melissa officinalis Essential Oil as a Potential Treatment for Oral Candidiasis
Lemon Verbena 📋 33489039Gastroprotective effects of both aqueous and ethanolic extracts of Lemon verbena leaves against indomethacin-induced gastric ulcer in rats
Lettuce 📋 36296971Molecular Effects of Iodine-Biofortified Lettuce in Human Gastrointestinal Cancer Cells
Lipase 📋25287168Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects
Long Pepper 📋 31281405Prebiotic Potential of Culinary Spices Used to Support Digestion and Bioabsorption
Madecassoside 📋 34180971Importance of telomere shortening in the pathogenesis of ulcerative colitis: A new treatment from the aspect of telomeres in intestinal epithelial cells
Mandarin Essential Oil 📋 35642325GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori
Marshmallow Root 📋 30554882A randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years
Matcha Tea 📋 36936880A randomized, double-blinded study evaluating effect of matcha green tea on human fecal microbiota
Mint 📋 27282663Mentha longifolia protects against acetic-acid induced colitis in rats
MUFA 📋 35220970Dietary intake of monounsaturated and polyunsaturated fatty acids is related to the reduced risk of esophageal squamous cell carcinoma
Nitrate 📋38733290Effects of dietary nitrate supplementation on oral health and associated markers of systemic health: a systematic review
Olive 📋36262974Antioxidant and Anticancer Potentials of the Olive and Sesame Mixture against Dimethylhydrazine-Induced Colorectal Cancer in Wistar Rats
Pantethine 📋11425046The effects of pantethine on fatty liver and fat distribution
Peas 📋 35262351Polyphenol Content of Green Pea ( Pisum sativum L.) Hull under In Vitro Digestion and Effects of Digestive Products on Anti-Inflammatory Activity and Intestinal Barrier in the Caco-2/Raw264.7 Coculture Model
Pelargonidin 📋 31696323Pelargonidin 3-glucoside-enriched Strawberry Attenuates Symptoms of DSS-induced Inflammatory Bowel Disease and Diet-Induced Metabolic Syndrome in Rats
Phellodendron 📋35463358Mechanism of Phellodendron and Anemarrhena Drug Pair on the Treatment of Liver Cancer Based on Network Pharmacology and Bioinformatics
Phosphatidylserine 📋33977946DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet
Phytoestrogens 📋 37719855Protective effect of phytoestrogens on nonalcoholic fatty liver disease in postmenopausal women
Pine Needle Essential Oil 📋19112901[Apoptosis and activity changes of telomerase induced by essential oil from pine needles in HepG2 cell line]
Rose Essential Oil 📋 38222701Effect of aromatherapy with rose essential oil on the nausea and vomiting in chemotherapy patients: a randomized controlled trial
Seafood 📋 32770320Omega-3 polyunsaturated fatty acids: a promising approach for the management of oral lichen planus
St. Johns Wort Oil 📋 31875751Use of Neem Oil and Hypericum perforatum for Treatment of Calcinosis-Related Skin Ulcers in Systemic Sclerosis
Sulfur 📋34725578Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb®) in Relieving Constipation
Sunflower 📋 34521318Helianthus Annuus L. Alleviates High-Fat Diet Induced Atherosclerosis by Regulating Intestinal Microbiota, Inhibiting Inflammation and Restraining Oxidative Stress
Terpenoids 📋 36615471Terpenoids: Natural Compounds for Non-Alcoholic Fatty Liver Disease (NAFLD) Therapy
Toothache Plant 📋 37671677The potential of Acmella oleracea as a nutraceutical source for the symptomatic treatment of Burning Mouth Syndrome
Vitamin B5 📋1810066[The use of pantothenic acid preparations in treating patients with viral hepatitis A]
Water Chestnut 📋35208513Evaluation of Dose-Dependent Obesity and Diabetes-Related Complications of Water Chestnut (Fruit of Trapa japonica) Extracts in Type II Obese Diabetic Mice Induced by 45% Kcal High-Fat Diet
Watercress 📋37057243Effect of Nasturtium Extract on Oral Cancer
Witch Hazel 📋22216935Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells
Wood Ear Mushrooms 📋 34787328Auricularia auricula-judae (Bull.) polysaccharides improve type 2 diabetes in HFD/STZ-induced mice by regulating the AKT/AMPK signaling pathways and the gut microbiota
Wormwood Essential Oil 📋 34268303Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway
Xylitol 📋35631164Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer
Yerba Mate 📋29548463Optimized Camellia sinensis var. sinensis, Ilex paraguariensis, and Aspalathus linearis blend presents high antioxidant and antiproliferative activities in a beverage model
Yiang Yiang Essential Oil 📋 31956259Antiviral Activity of Cananga odorata Against Hepatitis B Virus