Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
Curcumin | 📋 | ✍ | ⛔ | | 38674895 | The Possible Synergistic Pharmacological Effect of an Oral Berberine (BBR) and Curcumin (CUR) Complementary Therapy Alleviates Symptoms of Irritable Bowel Syndrome (IBS): Results from a Real-Life, Routine Clinical Practice Settings-Based Study |
Berberine | 📋 | ✍ | ⛔ | | 38729536 | Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells |
Vitamin D3 | 📋 | ✍ | ⛔ | | 38732118 | Vitamin D and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Novel Mechanistic Insights |
Resveratrol | 📋 | ✍ | ⛔ | | 38682953 | Resveratrol triggers autophagy-related apoptosis to inhibit the progression of colorectal cancer via inhibition of FOXQ1 |
Ginsenosides | 📋 | ✍ | ⛔ | | 38698858 | Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system |
Melatonin | 📋 | ✍ | ⛔ | | 38674926 | Mechanism of Action of Melatonin as a Potential Adjuvant Therapy in Inflammatory Bowel Disease and Colorectal Cancer |
Quercetin | 📋 | ✍ | ⛔ | | 38677479 | Higher dietary quercetin intake is associated with lower risk of adverse outcomes among individuals with inflammatory bowel disease in a prospective cohort study |
EGCG | 📋 | ✍ | ⛔ | | 38607257 | Tea Polyphenol Epigallocatechin Gallate Protects Against Nonalcoholic Fatty Liver Disease and Associated Endotoxemia in Rats via Modulating Gut Microbiota Dysbiosis and Alleviating Intestinal Barrier Dysfunction and Related Inflammation |
Vitamin C | 📋 | ✍ | ⛔ | | 38635545 | Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States |
Metformin | 📋 | ✍ | ⛔ | | 38530777 | Metformin boosts anti-tumor immunity and improves prognosis in upfront resected pancreatic cancer: an observational study |
Sulforaphane | 📋 | ✍ | ⛔ | | 38721140 | Sulforaphane protects against LPS-induced liver injury in mice by antagonizing oxidative stress and apoptosis through AMPK activation |
Probiotics | 📋 | ✍ | ⛔ | | 38542689 | Prebiotics and Probiotics for Gastrointestinal Disorders |
Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38712398 | Gallstone Dissolution Effects of Combination Therapy with n-3 Polyunsaturated Fatty Acids and Ursodeoxycholic Acid: A Randomized, Prospective, Preliminary Clinical Trial |
Ginseng | 📋 | ✍ | ⛔ | | 38698858 | Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system |
Luteolin | 📋 | ✍ | ⛔ | | 38674851 | Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention |
Vitamin E | 📋 | ✍ | ⛔ | | 38540888 | The Potential Role of Vitamin E and the Mechanism in the Prevention and Treatment of Inflammatory Bowel Disease |
Silymarin | 📋 | ✍ | ⛔ | | 38726410 | Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases-A comprehensive narrative review |
Fucoidan | 📋 | ✍ | ⛔ | | 38064857 | Fucoidan alleviated dextran sulfate sodium-induced ulcerative colitis with improved intestinal barrier, reshaped gut microbiota composition, and promoted autophagy in male C57BL/6 mice |
Apigenin | 📋 | ✍ | ⛔ | | 38619972 | Apigenin Suppresses MED28-Mediated Cell Growth in Human Liver Cancer Cells |
Goji Berry | 📋 | ✍ | ⛔ | | 38576495 | Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase |
Lycopene | 📋 | ✍ | ⛔ | | 38544357 | Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway |
Astaxanthin | 📋 | ✍ | ⛔ | | 38692895 | Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis Residue Alleviate Liver Injury in D-Galactose-induced Aging Mice through Gut-liver Axis |
Pterostilbene | 📋 | ✍ | ⛔ | | 38518635 | Pterostilbene suppresses gastric cancer proliferation and metastasis by inhibiting oncogenic JAK2/STAT3 signaling: In vitro and in vivo therapeutic intervention |
Cannabidiol | 📋 | ✍ | ⛔ | | 38711461 | Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways |
Ellagic Acid | 📋 | ✍ | ⛔ | | 38671932 | Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis |
Astragalosides | 📋 | ✍ | ⛔ | | 38689349 | Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier |
Reishi Mushrooms | 📋 | ✍ | ⛔ | | 38451046 | Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity |
Medicinal Plants | 📋 | | | | 38464716 | The additive effect of herbal medicines on lifestyle modification in the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis |
Genistein | 📋 | ✍ | ⛔ | | 38592519 | Genistein alleviates dextran sulfate sodium-induced colitis in mice through modulation of intestinal microbiota and macrophage polarization |
Baicalein | 📋 | ✍ | ⛔ | | 38727775 | Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model |
Emodin | 📋 | | ⛔ | | 38704789 | Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation |
Andrographolide | 📋 | | | | 38467318 | Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees |
Grape Seed extract | 📋 | ✍ | ⛔ | | 38419408 | Grape seed extract supplementation in non-alcoholic fatty liver disease |
Baicalin | 📋 | ✍ | ⛔ | | 38730240 | Baicalin enhances the chemotherapy sensitivity of oxaliplatin-resistant gastric cancer cells by activating p53-mediated ferroptosis |
Silibinin | 📋 | ✍ | | | 38222315 | Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis |
Thymoquinone | 📋 | | ⛔ | | 38652404 | N-methyl-D-aspartate receptors and thymoquinone induce apoptosis and alteration in mitochondria in colorectal cancer cells |
Astragalus Root | 📋 | ✍ | ⛔ | | 38621911 | [Astragali Radix-Curcumae Rhizoma inhibits colon cancer progression and enhances 5-FU efficacy by regulating hypoxia-inducible factors and tumor stem cells] |
Kaempferol | 📋 | ✍ | ⛔ | | 38596072 | Kaempferol-induced mitochondrial damage promotes NF-κB-NLRP3-caspase-1 signaling axis-mediated pyroptosis in gastric cancer cells |
Zinc | 📋 | ✍ | ⛔ | | 38012749 | The effects of zinc supplementation on the metabolic factors in patients with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled clinical trial |
Hesperidin | 📋 | ✍ | ⛔ | | 38477785 | Protective effects of hesperidin in gastric damage caused by experimental ischemia-reperfusion injury model in rats |
N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 38540289 | The Use and Potential Benefits of N-Acetylcysteine in Non-Acetaminophen Acute Liver Failure: An Etiology-Based Review |
Bee Propolis | 📋 | ✍ | ⛔ | | 38710295 | Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials |
Licorice Root | 📋 | ✍ | ⛔ | | 38641080 | Wighteone, a prenylated flavonoid from licorice, inhibits growth of SW480 colorectal cancer cells by allosteric inhibition of Akt |
Ginger | 📋 | ✍ | ⛔ | | 38461442 | Effect of ginger and P6 acupressure on chemotherapy-induced nausea and vomiting: a randomized controlled study |
Nobiletin | 📋 | ✍ | | | 38547624 | Nobiletin targets SREBP1/ACLY to induce autophagy-dependent cell death of gastric cancer cells through PI3K/Akt/mTOR signaling pathway |
Anthocyanins | 📋 | ✍ | ⛔ | | 38290991 | Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells |
Phytochemicals | 📋 | | | | 38690008 | A comprehensive review on phytochemicals in the treatment and prevention of pancreatic cancer: Focusing on their mechanism of action |
Selenium | 📋 | ✍ | ⛔ | | 38691983 | Genetic prediction of micronutrient levels and the risk of colorectal polyps: A mendelian randomization study |
Fisetin | 📋 | ✍ | ⛔ | | 38191834 | Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS-induced murine model of colitis |
Aloe Vera | 📋 | ✍ | ⛔ | | 38595509 | Efficacy of Aloe Vera, Amlexanox (5%), and Triamcinolone Acetonide (0.1%) in the Management of Oral Lichen Planus |
Butyrate | 📋 | | ⛔ | | 38533461 | The postbiotic sodium butyrate synergizes the antiproliferative effects of dexamethasone against the AGS gastric adenocarcinoma cells |
Gingerol | 📋 | ✍ | | | 38565569 | 6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway |
Naringenin | 📋 | ✍ | ⛔ | | 38583080 | A narrative review on therapeutic potential of naringenin in colorectal cancer: Focusing on molecular and biochemical processes |
Nigella Sativa | 📋 | ✍ | ⛔ | | 38578469 | Determination of anti-cancer effects of Nigella sativa seed oil on MCF7 breast and AGS gastric cancer cells |
Aspirin | 📋 | | ⛔ | | 38601481 | Effects of aspirin on colon cancer using quantitative proteomic analysis |
Food | 📋 | | | | 38329234 | Causal relationships between dietary habits and Barrett's esophagus risk: a univariable and multivariable Mendelian randomization study |
Micronutrients | 📋 | | ⛔ | | 38703282 | A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways |
Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 38331851 | Efficacy and safety of peppermint oil for the treatment in Japanese patients with irritable bowel syndrome: a prospective, open-label, and single-arm study |
Piperine | 📋 | ✍ | ⛔ | | 38547097 | Piperine alleviates nonalcoholic steatohepatitis by inhibiting NF-κB-mediated hepatocyte pyroptosis |
Pomegranate | 📋 | | ⛔ | | 38661445 | Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites |
Dandelion | 📋 | ✍ | ⛔ | | 38568379 | Potentialities of dandelion (Taraxacum mongolicum Hand.-Mazz.) flower extracts on gastric protection against Helicobacter pylori and characterization of its bioactive constituents |
Moringa Oleifera | 📋 | ✍ | ⛔ | | 38493756 | Modulatory effects of Moringa oleifera leaf extract on sodium nitrate-induced experimental colitis via regulation of P53, Ki-67 and PCNA biomarkers |
Gallic Acid | 📋 | | ⛔ | | 38636693 | Gallic acid mitigates intestinal inflammation and loss of tight junction protein expression using a 2D-Caco-2 and RAW 264.7 co-culture model |
L-Glutamine | 📋 | ✍ | ⛔ | | 38656560 | L-Glutamine Substantially Improves 5-Fluorouracil-Induced Intestinal Mucositis by Modulating Gut Microbiota and Maintaining the Integrity of the Gut Barrier in Mice |
Mulberry | 📋 | | ⛔ | | 38707917 | Mulberry leaf extract inhibits obesity and protects against diethylnitrosamine-induced hepatocellular carcinoma in rats |
Dihydromyricetin | 📋 | ✍ | ⛔ | | 38532480 | Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway |
Fish Oil | 📋 | ✍ | ⛔ | | 38486044 | Fish oil ameliorates ethanol-induced gastric injury in rat by modulating gene related to apoptosis |
Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 37085597 | Green tea extract prevents CPT-11-induced diarrhea by regulating the gut microbiota |
Magnesium | 📋 | ✍ | ⛔ | | 38509591 | Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma |
Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 38107049 | Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma ( in vitro study) |
Puerarin | 📋 | ✍ | ⛔ | | 38674860 | Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice |
Salidroside | 📋 | | | | 38436092 | Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules |
Spirulina | 📋 | ✍ | ⛔ | | 38694088 | Amino acid HPLC-FLD analysis of spirulina and its protective mechanism against the combination of obesity and colitis in wistar rats |
Capsaicin | 📋 | ✍ | ⛔ | | 38706122 | Capsaicin reverses cisplatin resistance in tongue squamous cell carcinoma by inhibiting the Warburg effect and facilitating mitochondrial-dependent apoptosis via the AMPK/AKT/mTOR axis |
Dihydroartemisinin | 📋 | | | | 38713259 | Target prediction and potential application of dihydroartemisinin on hepatocarcinoma treatment |
Kiwifruit | 📋 | ✍ | ⛔ | | 38144866 | Lactiplantibacillus plantarum fermentation enhanced the protective effect of kiwifruit on intestinal injury in rats: Based on mitochondrial morphology and function |
Licochalcones | 📋 | | | | 38148556 | Licochalcone C Inhibits the Growth of Human Colorectal Cancer HCT116 Cells Resistant to Oxaliplatin |
Walnut | 📋 | | ⛔ | | 38068724 | The Gastroprotective Effect of Walnut Peptides: Mechanisms and Impact on Ethanol-Induced Acute Gastric Mucosal Injury in Mice |
Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38708558 | Chlorogenic acid and its isomers attenuate NAFLD by mitigating lipid accumulation in oleic acid-induced HepG2 cells and high-fat diet- fed zebrafish |
Chrysin | 📋 | ✍ | ⛔ | | 37167529 | Chrysin prevents inflammation-coinciding liver steatosis via AMPK signalling |
Naringin | 📋 | ✍ | ⛔ | | 38557865 | Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation |
Paeoniflorin | 📋 | | | | 38634140 | Activation of ASIC3/ERK pathway by paeoniflorin improves intestinal fluid metabolism and visceral sensitivity in slow transit constipated rats |
Blueberry | 📋 | ✍ | ⛔ | | 38107049 | Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma ( in vitro study) |
Crocin | 📋 | ✍ | ⛔ | | 37718528 | Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo |
Skullcap | 📋 | ✍ | ⛔ | | 38616754 | Network Pharmacology, Molecular Docking Analysis and Molecular Dynamics Simulation of Scutellaria baicalensis in the Treatment of Liver Fibrosis |
Apple | 📋 | | ⛔ | | 37129213 | Apple juice relieves loperamide-induced constipation in rats by downregulating the intestinal apical sodium-dependent bile acid transporter ASBT |
Indian Gooseberry | 📋 | | ⛔ | | 38158054 | Phyllanthus emblica L. polysaccharides ameliorate colitis via microbiota modulation and dual inhibition of the RAGE/NF-κB and MAPKs signaling pathways in rats |
Inulin | 📋 | ✍ | ⛔ | | 38473746 | Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease |
TUDCA | 📋 | ✍ | ⛔ | | 38192027 | Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner |
Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 38700384 | Glycyrrhizic acid attenuates the malignant biological properties of nonalcoholic fatty liver disease-related hepatocellular carcinoma |
Polyphenols | 📋 | | | | 38625672 | Liver cancer wars: plant-derived polyphenols strike back |
Fucoxanthin | 📋 | ✍ | ⛔ | | 38669300 | Molecular Mechanisms of Fucoxanthin in Alleviating Lipid Deposition in Metabolic Associated Fatty Liver Disease |
Galangin | 📋 | | | | 38602402 | Galangin Prevents Against Ethanol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation via NF-κB/MAPK Signaling Pathways in Mice and Caco-2 Cells |
Ginger extract | 📋 | ✍ | ⛔ | | 36865747 | Oral Administration Evaluation of the Hydro-Ethanolic Extract of Ginger (Rhizome of Zingiber officinale) against Postoperative-Induced Peritoneal Adhesion: Investigating the Role of Anti-Inflammatory and Antioxidative Effects |
Turmeric | 📋 | ✍ | ⛔ | | 38621911 | [Astragali Radix-Curcumae Rhizoma inhibits colon cancer progression and enhances 5-FU efficacy by regulating hypoxia-inducible factors and tumor stem cells] |
Allicin | 📋 | ✍ | ⛔ | | 38728949 | Allicin regulates Sestrin2 ubiquitination to affect macrophage autophagy and senescence, thus inhibiting the growth of hepatoma cells |
Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 38430210 | Docosahexaenoic Acid Modulates Nonalcoholic Fatty Liver Disease by Suppressing Endocannabinoid System |
Psyllium | 📋 | ✍ | ⛔ | | 36828279 | PSYLLIUM FIBER PROTECTS AGAINST COLITIS VIA ACTIVATION OF BILE ACID SENSOR FXR |
Schisandra | 📋 | ✍ | ⛔ | | 38585559 | A combined extract containing Schisandra chinensis (SCE) reduced hepatic triglyceride accumulation in rats fed a high-sucrose diet |
Vitamin A | 📋 | ✍ | ⛔ | | 38492186 | Immunomodulatory and Anti-Inflammatory Effects of Vitamin A and Tryptophan on Monocyte-Derived Dendritic Cells Stimulated with Gliadin in Celiac Disease Patients |
Wogonin | 📋 | ✍ | ⛔ | | 38518634 | Wogonin improves colitis by activating the AhR pathway to regulate the plasticity of ILC3/ILC1 |
Arctigenin | 📋 | | | | 38679116 | Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice |
Ginkgo Biloba | 📋 | ✍ | ⛔ | | 38727268 | L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism |
Lipoic Acid | 📋 | ✍ | ⛔ | | 38245790 | (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease |
Raspberry | 📋 | ✍ | ⛔ | | 38340928 | Raspberry polysaccharides attenuate hepatic inflammation and oxidative stress in diet-induced obese mice by enhancing butyrate-mediated intestinal barrier function |
Beta-Carotene | 📋 | ✍ | ⛔ | | 38691983 | Genetic prediction of micronutrient levels and the risk of colorectal polyps: A mendelian randomization study |
Garlic | 📋 | ✍ | ⛔ | | 38223588 | Garlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials |
Patchouli | 📋 | ✍ | ⛔ | | 37513952 | Probiotic Formulations Containing Fixed and Essential Oils Ameliorates SIBO-Induced Gut Dysbiosis in Rats |
Tanshinone | 📋 | | | | 38621946 | [Tanshinone â…¡_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease] |
Atractylodes | 📋 | ✍ | ⛔ | | 38663104 | The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats |
Coffee | 📋 | ✍ | ⛔ | | 38346920 | Coffee consumption is associated with a reduced risk of colorectal cancer recurrence and all-cause mortality |
Cranberry | 📋 | ✍ | ⛔ | | 38139823 | Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model |
Rutin | 📋 | ✍ | ⛔ | | 38394735 | Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway |
Honokiol | 📋 | | | | 38402928 | The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity |
Lactobacillus plantarum | 📋 | | ⛔ | | 38528541 | Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis |
Coptis Chinensis | 📋 | | ⛔ | | 38729536 | Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells |
Flavonoids | 📋 | | ⛔ | | 38700837 | Harnessing Plant Flavonoids to Fight Pancreatic Cancer |
Honey | 📋 | ✍ | ⛔ | | 38710295 | Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials |
CoQ10 | 📋 | ✍ | ⛔ | | 37701221 | The effect of coenzyme Q10 supplementation on liver enzymes: A systematic review and meta-analysis of randomized clinical trials |
Maitake Mushrooms | 📋 | | ⛔ | | 37351508 | Mushroom polysaccharides from Grifola frondosa (Dicks.) Gray and Inonotus obliquus (Fr.) Pilat ameliorated dextran sulfate sodium-induced colitis in mice by global modulation of systemic metabolism and the gut microbiota |
Chokeberry | 📋 | ✍ | ⛔ | | 36344052 | Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota |
Cordycepin | 📋 | | | | 38589021 | Cordycepin Enhanced Therapeutic Potential of Gemcitabine against Cholangiocarcinoma via Downregulating Cancer Stem-Like Properties |
Green Tea | 📋 | ✍ | ⛔ | | 38370081 | Long-term drinking of green tea combined with exercise improves hepatic steatosis and obesity in male mice induced by high-fat diet |
Rosmarinic Acid | 📋 | ✍ | | | 37749237 | Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis |
Bromelain | 📋 | ✍ | ⛔ | | 37803248 | Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells |
Cinnamon | 📋 | ✍ | ⛔ | | 38466698 | Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses |
Grape | 📋 | | ⛔ | | 37511015 | Synergistic Effects of Vitis vinifera L. and Centella asiatica against CCl4-Induced Liver Injury in Mice |
Hesperetin | 📋 | | | | 37109513 | Hesperetin and Capecitabine Abate 1,2 Dimethylhydrazine-Induced Colon Carcinogenesis in Wistar Rats via Suppressing Oxidative Stress and Enhancing Antioxidant, Anti-Inflammatory and Apoptotic Actions |
L-Carnitine | 📋 | ✍ | ⛔ | | 38727268 | L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism |
Prebiotics | 📋 | ✍ | ⛔ | | 38613035 | Prebiotic Strategies to Manage Lactose Intolerance Symptoms |
Schisandrins | 📋 | | | | 38500179 | The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages |
Urolithins | 📋 | | | | 38622949 | Urolithin A affects cellular migration and modulates matrix metalloproteinase expression in colorectal cancer cells |
Caffeine | 📋 | ✍ | ⛔ | | 38680003 | Evaluation of the Combined Effect of Caffeine and 5-Fluorouracil on Colorectal Cancer Cell Lines |
Dihydroquercetin | 📋 | | | | 38552433 | Dihydroquercetin improves experimental acute liver failure by targeting ferroptosis and mitochondria-mediated apoptosis through the SIRT1/p53 axis |
Eugenol | 📋 | | | | 38480500 | Eugenol Possesses Colitis Protective Effects: Impacts on the TLR4/MyD88/NF-[Formula: see text]B Pathway, Intestinal Epithelial Barrier, and Macrophage Polarization |
Ferulic Acid | 📋 | ✍ | ⛔ | | 38293309 | Ferulic acid interventions ameliorate NDEA-CCl4-induced hepatocellular carcinoma via Nrf2 and p53 upregulation and Akt/PKB-NF-κB-TNF-α pathway downregulation in male Wistar rats |
Peony | 📋 | | ⛔ | | 38186470 | Atractylodes macrocephala-Paeonia lactiflora Class Formula for the Treatment of Irritable Bowel Syndrome: A Systematic Review With Meta-Analysis and Trial Sequential Analysis |
Red Sage | 📋 | ✍ | ⛔ | | 38636259 | Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits |
Cinnamaldehyde | 📋 | | | | 38663778 | Cinnamaldehyde: An effective component of Cinnamomum cassia inhibiting Helicobacter pylori |
Fiber | 📋 | ✍ | ⛔ | | 38730369 | Exploring the association between dietary fiber intake and hepatic steatosis: insights from NHANES |
Hydroxytyrosol | 📋 | | | | 38680105 | Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition |
Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 38729053 | Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease |
Olive Oil | 📋 | ✍ | ⛔ | | 38493431 | Evaluation of the protective and therapeutic effects of extra virgin olive oil rich in phenol in experimental model of neonatal necrotizing enterocolitis by clinical disease score, ınflammation, apoptosis, and oxidative stress markers |
Salvianolic Acid | 📋 | | | | 38674860 | Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice |
Wormwood | 📋 | ✍ | ⛔ | | 38139333 | Artemisia annua L. Polyphenols Enhance the Anticancer Effect of β-Lapachone in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells |
Aloe-Emodin | 📋 | | | | 37956613 | Aloe-emodin destroys the biofilm of Helicobacter pylori by targeting the outer membrane protein 6 |
Andrographis | 📋 | ✍ | ⛔ | | 38467318 | Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees |
Apple Polyphenols | 📋 | | ⛔ | | 38055797 | Preventive Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are Related to the Regulation of Hepatic Lipid Metabolism, Autophagy, and Gut Microbiota in Aged Mice |
Chamomile | 📋 | ✍ | ⛔ | | 38710295 | Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials |
Diosmin | 📋 | ✍ | ⛔ | | 38500992 | Diosmin alleviates ulcerative colitis in mice by increasing Akkermansia muciniphila abundance, improving intestinal barrier function, and modulating the NF-κB and Nrf2 pathways |
Isoliquiritigenin | 📋 | | | | 38671579 | Isoliquiritigenin limits inflammasome activation of macrophage via docking into Syk to alleviate murine non-alcoholic fatty liver disease |
Oleuropein | 📋 | | | | 38436159 | Oleuropein, a phenolic component of Olea europaea L. ameliorates CCl4-induced liver injury in rats through the regulation of oxidative stress and inflammation |
Beta-Glucan | 📋 | ✍ | ⛔ | | 38674816 | Consumption of Feed Supplemented with Oat Beta-Glucan as a Chemopreventive Agent against Colon Cancerogenesis in Rats |
Boswellic Acid | 📋 | ✍ | ⛔ | | 38513840 | Acetyl-11-keto-beta-boswellic acid inhibits cell proliferation and growth of oral squamous cell carcinoma via RAB7B-mediated autophagy |
Gardenia | 📋 | | ⛔ | | 38090678 | Gardenia Iridoid Glucosides Protect Against α-Naphthalene Isothiocya-Nate-Induced Cholestatic Rats Through Activation of the FXR-SHP Signaling Pathway |
Mangiferin | 📋 | | ⛔ | | 38191592 | Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat's colon by augmentation of apoptotic proteins and antioxidant mechanisms |
Tea | 📋 | | | | 37867491 | Association of tea and its extracts with colorectal adenomas: meta-analysis and systematic review |
Carnosic Acid | 📋 | | | | 36979808 | Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation |
Catechins | 📋 | | | | 37732516 | Catechin hydrate ameliorates cerulein‑induced chronic pancreatitis via the inactivation of TGF‑β/Smad2 signaling |
Diosgenin | 📋 | | | | 38458369 | Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses |
Hawthorn | 📋 | ✍ | ⛔ | | 38601914 | A study on the treatment effects of Crataegus pinnatifida polysaccharide on non-alcoholic fatty liver in mice by modulating gut microbiota |
NMN | 📋 | ✍ | ⛔ | | 38729053 | Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease |
Saffron | 📋 | ✍ | ⛔ | | 38146566 | Effectiveness of the Combination of Probiotic Supplementation on Motor Symptoms and Constipation in Parkinson's Disease |
UDCA | 📋 | ✍ | ⛔ | | 38712398 | Gallstone Dissolution Effects of Combination Therapy with n-3 Polyunsaturated Fatty Acids and Ursodeoxycholic Acid: A Randomized, Prospective, Preliminary Clinical Trial |
Withaferin A | 📋 | | | | 38537439 | Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells |
Beta-Sitosterol | 📋 | ✍ | ⛔ | | 38156844 | The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis |
Betaine | 📋 | ✍ | ⛔ | | 38695854 | Use of Betaine HCl with Pepsin in Esophageal Cancer Patient: A Case Report |
Burdock | 📋 | | ⛔ | | 38018589 | Long-term oral administration of burdock fructooligosaccharide alleviates DSS-induced colitis in mice by mediating anti-inflammatory effects and protection of intestinal barrier function |
Cordyceps | 📋 | ✍ | ⛔ | | 38582477 | Elucidation of antioxidant activities of intracellular and extracellular polysaccharides from Cordyceps militaris in vitro and their protective effects on ulcerative colitis in vivo |
Frankincense | 📋 | ✍ | ⛔ | | 37719039 | Water extract of frankincense and myrrh inhibits liver cancer progression and epithelial‑mesenchymal transition through Wnt/β‑catenin signaling |
Procyanidins | 📋 | | ⛔ | | 37831732 | The combined anticancer of peanut skin procyanidins and resveratrol to CACO-2 colorectal cancer cells |
Thymol | 📋 | ✍ | ⛔ | | 38376297 | Induction of G0/G1 phase cell cycle arrest and apoptosis by thymol through ROS generation and caspase-9/-3 activation in breast and colorectal cancer cell lines |
Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 38435630 | Alpha-Linolenic Acid Ameliorates Cognitive Impairment and Liver Damage Caused by Obesity |
Amygdalin | 📋 | ✍ | ⛔ | | 38680005 | The Cytotoxic Effect of Ciprofloxacin Laetrile Combination on Esophageal Cancer Cell Line |
Black Tea | 📋 | ✍ | ⛔ | | 37940573 | The Effects of Black Tea Consumption on Intestinal Microflora-A Randomized Single-Blind Parallel-Group, Placebo-Controlled Study |
Carvacrol | 📋 | ✍ | ⛔ | | 38605312 | The inhibitory effects of carvacrol, nystatin, and their combination on oral candidiasis isolates |
Emu Oil | 📋 | ✍ | ⛔ | | 37402926 | Emu Oil and zinc monoglycerolate independently reduce disease severity in a rat model of ulcerative colitis |
Geniposide | 📋 | | | | 38069009 | Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the TLR4 and AMPK Signaling Pathways |
Mangosteen | 📋 | ✍ | ⛔ | | 36098087 | Garcinia mangostana and α-Mangostin Revive Ulcerative Colitis-Modified Hepatic Cytochrome P450 Profiles in Mice |
Polydatin | 📋 | ✍ | | | 36678905 | Chemopreventive and Anticancer Role of Resveratrol against Oral Squamous Cell Carcinoma |
Shogaol | 📋 | | | | 38257332 | 6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress |
Taurine | 📋 | ✍ | ⛔ | | 38681990 | Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis |
Acai Berry | 📋 | ✍ | ⛔ | | 38428258 | A polyphenol-rich açaà seed extract protects against 5-fluorouracil-induced intestinal mucositis in mice through the TLR-4/MyD88/PI3K/mTOR/NF-κBp65 signaling pathway |
Angelica | 📋 | ✍ | ⛔ | | 37563852 | Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver |
Artemisinin | 📋 | | | | 38409843 | Artesunate Inhibits Lipid Accumulation and Inflammation by Regulating the NLRP3 Inflammasome in Nonalcoholic Fatty Liver Disease |
Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 37887366 | Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study |
Flaxseed | 📋 | ✍ | ⛔ | | 38398791 | Beneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease |
Pine Bark | 📋 | ✍ | ⛔ | | 38600993 | Effect of pine bark extract and its phenolic compounds on selected pathogenic and probiotic bacterial strains |
Punicalagin | 📋 | ✍ | ⛔ | | 38455601 | The synergistic effect of oxaliplatin and punicalagin on colon cancer cells Caco-2 death |
Bee Venom | 📋 | ✍ | ⛔ | | 38445441 | Melittin as an Activator of the Autophagy and Unfolded Protein Response Pathways in Colorectal HCT116 Cell Line |
Blackcurrant | 📋 | ✍ | ⛔ | | 36900589 | Blackcurrant Alleviates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice |
Carotenoids | 📋 | ✍ | ⛔ | | 38134087 | Association between carotenoid intake and metabolic dysfunction-associated fatty liver disease among US adults: A cross-sectional study |
Graviola | 📋 | ✍ | ⛔ | | 38075540 | In vitro Evaluation of Cytotoxic Effects of Methanolic Leaf Extracts of Annona muricata on Oral Squamous Cell Carcinoma-15 Cell Lines and its Effect On Expression of Bcl 2-associated X protein, B-cell C/Lymphoma 2 and p53 Genes |
Icaritin | 📋 | | | | 38431053 | Icaritin activates p53 and inhibits aerobic glycolysis in liver cancer cells |
L-Arginine | 📋 | ✍ | ⛔ | | 37739730 | Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study |
Ollive Leaf extract | 📋 | ✍ | ⛔ | | 38467548 | Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy |
Pectin | 📋 | ✍ | ⛔ | | 36615814 | Pectin in Metabolic Liver Disease |
Pu-erh Tea | 📋 | ✍ | ⛔ | | 36592713 | Pu-erh tea alleviated colitis-mediated brain dysfunction by promoting butyric acid production |
Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 38257149 | Hepatoprotection of a Standardized Extract of Cultured Lentinula edodes Mycelia against Liver Injury Induced by Ischemia-Reperfusion and Partial Hepatectomy |
Stinging Nettle | 📋 | ✍ | ⛔ | | 38623153 | Effect of vitamin D3 and a stinging nettle extract on the gastric tissue of rats administered with trinitrobenzene sulfonic acid |
Aloin | 📋 | | | | 38038700 | Aloin Attenuates Oxidative Stress, Inflammation, and CCl4-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling |
Asiatic Acid | 📋 | | | | 37375849 | Asiatic Acid Inhibits Nasopharyngeal Carcinoma Cell Viability and Migration via Suppressing STAT3 and Claudin-1 |
Betulinic Acid | 📋 | | | | 38261922 | Betulinic acid arrests cell cycle at G2/M phase by up-regulating metallothionein 1G inhibiting proliferation of colon cancer cells |
Chlorella | 📋 | ✍ | ⛔ | | 38704764 | Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study |
Myricetin | 📋 | | ⛔ | | 38483540 | Myricetin Induces Ferroptosis and Inhibits Gastric Cancer Progression by Targeting NOX4 |
Myrrh | 📋 | ✍ | ⛔ | | 38044939 | Myrrh protects against IL-13-induced epithelial barrier breakdown in HT-29/B6 cells |
Poria Mushrooms | 📋 | ✍ | | | 38731645 | Poria cocos Attenuated DSS-Induced Ulcerative Colitis via NF-κB Signaling Pathway and Regulating Gut Microbiota |
Rapamycin | 📋 | ✍ | | | 38548510 | Beneficial Effect of Rapamycin on Liver Fibrosis in a Mouse Model (C57bl/6 Mouse) |
Retinoic Acid | 📋 | | | | 38239861 | Potential antitumour effect of all-trans retinoic acid on regorafenib-treated human colon cancer cell lines |
Tangeretin | 📋 | | | | 38022093 | Tangeretin's Anti-apoptotic Signaling Mechanisms in Oral Cancer Cells: In Vitro Anti-cancer Activity |
Ursolic Acid | 📋 | ✍ | ⛔ | | 38623614 | Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against non-alcoholic fatty liver disease |
Vitamin B6 | 📋 | ✍ | ⛔ | | 38698325 | Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway |
Beta-Cryptoxanthin | 📋 | | | | 37049698 | Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes |
Bilberry | 📋 | ✍ | ⛔ | | 35889832 | Protective Effect of Bilberry Anthocyanin Extracts on Dextran Sulfate Sodium-Induced Intestinal Damage in Drosophila melanogaster |
Cocoa | 📋 | ✍ | ⛔ | | 37836487 | Dark Chocolate Intake Positively Modulates Gut Permeability in Elite Football Athletes: A Randomized Controlled Study |
L-Theanine | 📋 | ✍ | ⛔ | | 38611425 | The Protective Effects of L-Theanine against Epigallocatechin Gallate-Induced Acute Liver Injury in Mice |
L-Tryptophan | 📋 | ✍ | ⛔ | | 38613060 | A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients |
Magnolol | 📋 | | | | 38660717 | Magnolol promotes the autophagy of esophageal carcinoma cells by upregulating HACE1 gene expression |
Phloretin | 📋 | | | | 37744933 | Metagenomic signatures reveal the key role of phloretin in amelioration of gut dysbiosis attributed to metabolic dysfunction-associated fatty liver disease by time-dependent modulation of gut microbiome |
Vitamin B9 | 📋 | ✍ | ⛔ | | 37327296 | Effects of folic acid supplementation on chronic atrophic gastritis based on MTHFR C677T polymorphism |
Acacetin | 📋 | | | | 38571642 | Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification |
Acetyl-L-Carnitine | 📋 | ✍ | ⛔ | | 38369215 | The intestinal microbial metabolite acetyl l-carnitine improves gut inflammation and immune homeostasis via CADM2 |
BCAA | 📋 | ✍ | ⛔ | | 37836474 | Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease |
Calycosin | 📋 | | | | 37506138 | Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF-κB pathway: An in vitro study |
D-Mannose | 📋 | ✍ | ⛔ | | 38529272 | Mannose enhances intestinal immune barrier function and dextran sulfate sodium salt-induced colitis in mice by regulating intestinal microbiota |
DHEA | 📋 | ✍ | ⛔ | | 37669399 | Anorexia nervosa and adrenal hormones: a systematic review and meta-analysis |
Escin | 📋 | ✍ | ⛔ | | 36905866 | Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy |
Formononetin | 📋 | | | | 38185065 | Formononetin promotes fatty acid β-oxidation to treat non-alcoholic steatohepatitis through SIRT1/PGC-1α/PPARα pathway |
Guava | 📋 | | ⛔ | | 36134391 | Guava Leaf Extract Suppresses Fructose Mediated Non-Alcoholic Fatty Liver Disease in Growing Rats |
Roselle | 📋 | ✍ | ⛔ | | 38376437 | Antioxidant and Antineoplastic Activities of Hibiscus sabdariffa Linn. Petal Extracts against Oral Squamous Cell Carcinoma Cell Line |
Royal Jelly | 📋 | ✍ | ⛔ | | 38337678 | Exploring the Therapeutic Potential of Royal Jelly in Metabolic Disorders and Gastrointestinal Diseases |
Scutellarin | 📋 | | | | 38622131 | Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression |
Bergamot | 📋 | ✍ | ⛔ | | 37820919 | Bergamot polysaccharides relieve DSS-induced ulcerative colitis via regulating the gut microbiota and metabolites |
Calcium | 📋 | ✍ | ⛔ | | 38456354 | Implication of calcium supplementations in health and diseases with special focus on colorectal cancer |
Camellia | 📋 | | ⛔ | | 35178105 | Camelina sativa Oil Treatment Alleviates Castor Oil-Induced Diarrhea in ICR Mice by Regulating Intestinal Flora Composition |
Dioscin | 📋 | | | | 38085503 | Dioscin Impedes Proliferation, Metastasis and Enhances Autophagy of Gastric Cancer Cells via Regulating the USP8/TGM2 Pathway |
Glycyrrhetinic Acid | 📋 | | | | 38244730 | Ursodeoxycholic acid and 18β-glycyrrhetinic acid alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells |
Lingonberry | 📋 | | ⛔ | | 35802745 | Inhibitory effect of lingonberry extract on HepG2 cell proliferation, apoptosis, migration, and invasion |
Milk Thistle | 📋 | ✍ | ⛔ | | 36788749 | Combinatorial treatment with Silybum marianum essential oil enhances the therapeutic efficacy of a 5-fluorouracil base therapy for hepatocellular carcinoma |
Oats | 📋 | | ⛔ | | 38140314 | Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis |
Sea Buckthorn | 📋 | ✍ | ⛔ | | 37833431 | Hippophae rhamnoides reverses decreased CYP2D6 expression in rats with BCG-induced liver injury |
St. Johns Wort | 📋 | ✍ | ⛔ | | 37950737 | Cytotoxic and anti-metastatic effects of Hypericum perforatum olive oil extract in colorectal cancer cells and human bone marrow derived stem cells |
Strawberry | 📋 | ✍ | ⛔ | | 36901426 | Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism |
Zingerone | 📋 | | | | 37766888 | Zingerone attenuates intestinal injury and colitis caused by a high-fat diet through Nrf2 signaling regulation |
Antioxidants | 📋 | | ⛔ | | 38673974 | Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease |
Barberry | 📋 | ✍ | ⛔ | | 38732003 | Berberis vulgaris L. Root Extract as a Multi-Target Chemopreventive Agent against Colon Cancer Causing Apoptosis in Human Colon Adenocarcinoma Cell Lines |
Broccoli | 📋 | | ⛔ | | 38458274 | The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders |
Crocetin | 📋 | | | | 35094239 | Crocetin alleviates the caerulein-induced apoptosis and inflammation in AR42J cells by activating SIRT1 via NF-κB |
Cryptotanshinone | 📋 | | | | 37435898 | Cryptotanshinone ameliorates hemorrhagic shock-induced liver injury via activating the Nrf2 signaling pathway |
Daidzein | 📋 | ✍ | ⛔ | | 37759583 | Protective Effect of Daidzein against Diethylnitrosamine/Carbon Tetrachloride-Induced Hepatocellular Carcinoma in Male Rats |
Diosmetin | 📋 | | | | 37796396 | Diosmetin induces apoptosis and protective autophagy in human gastric cancer HGC-27 cells via the PI3K/Akt/FoxO1 and MAPK/JNK pathways |
Folate | 📋 | ✍ | ⛔ | | 37733056 | Correlation of Nonalcoholic Fatty Liver Disease with Dietary Folate and Serum Folate in U.S. Adults: Cross-Sectional Analyses from National Health and Nutrition Examination Survey 2009-2018 |
Kudzu Root | 📋 | ✍ | ⛔ | | 36384052 | Induction of autophagy via the PI3K/Akt/mTOR signaling pathway by Pueraria flavonoids improves non-alcoholic fatty liver disease in obese mice |
Limonin | 📋 | | | | 38455137 | Limonin inhibits the stemness of cancer stem-like cells derived from colorectal carcinoma cells potentially via blocking STAT3 signaling |
Paeonol | 📋 | | | | 38574779 | Paeonol attenuates nonalcoholic steatohepatitis by regulating intestinal flora and AhR/NLRP3/Caspase-1 metabolic pathway |
Perilla | 📋 | ✍ | | | 37834377 | Therapeutic Effects of Perilla Phenols in Oral Squamous Cell Carcinoma |
Vitamin B12 | 📋 | ✍ | ⛔ | | 37275922 | Protective role of vitamin B12 on acetic acid induced colitis in rats |
Vitamin B2 | 📋 | ✍ | ⛔ | | 38597225 | Riboflavin ameliorates intestinal inflammation via immune modulation and alterations of gut microbiota homeostasis in DSS-colitis C57BL/6 mice |
Aged Garlic | 📋 | ✍ | ⛔ | | 34136174 | Synergistic effects of black ginseng and aged garlic extracts for the amelioration of nonalcoholic fatty liver disease (NAFLD) in mice |
Cinnamon Essential Oil | 📋 | ✍ | ⛔ | | 38666995 | Efficacy and Synergistic Potential of Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum L. Merr. & Perry) Essential Oils to Control Food-Borne Pathogens in Fresh-Cut Fruits |
Conjugated Linoleic Acid | 📋 | ✍ | ⛔ | | 36132168 | Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells |
Echinacea | 📋 | ✍ | ⛔ | | 38732552 | Echinacea purpurea Polysaccharide Ameliorates Dextran Sulfate Sodium-Induced Colitis by Restoring the Intestinal Microbiota and Inhibiting the TLR4-NF-κB Axis |
Essential Oils | 📋 | | ⛔ | | 37299569 | The Potential of Natural Oils to Improve Inflammatory Bowel Disease |
Fruits | 📋 | | | | 38019753 | Causal association between dietary factors and esophageal diseases: A Mendelian randomization study |
Ginkgolides | 📋 | | | | 36375817 | Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora |
Icariin | 📋 | ✍ | | | 38621977 | [Study on mechanism of icariin-induced ferroptosis in HepG2 hepatoma carcinoma cells through PPARG/FABP4/GPX4 pathway] |
Isorhamnetin | 📋 | | | | 38612598 | Isorhamnetin Alleviates Mitochondrial Injury in Severe Acute Pancreatitis via Modulation of KDM5B/HtrA2 Signaling Pathway |
MSM | 📋 | ✍ | ⛔ | | 38099147 | Methylsulfonylmethane ameliorates metabolic-associated fatty liver disease by restoring autophagy flux via AMPK/mTOR/ULK1 signaling pathway |
Orange | 📋 | | ⛔ | | 32570775 | Flavonoid-Rich Orange Juice Intake and Altered Gut Microbiome in Young Adults with Depressive Symptom: A Randomized Controlled Study |
Parthenolide | 📋 | | | | 38703207 | Parthenolide alleviates indomethacin-induced gastric ulcer in rats via antioxidant, anti-inflammatory, and antiapoptotic activities |
Piperlongumine | 📋 | | | | 38452870 | Anti-cancer agent piperlongumine is an inhibitor of transient receptor potential melastatin 7 channel in oral squamous cell carcinoma |
Rhubarb | 📋 | | ⛔ | | 38579425 | Mid-infrared spectroscopic identification of the right-baked rhubarb for ulcerative colitis therapy |
Rosemary | 📋 | ✍ | ⛔ | | 38481883 | Anticancer Effects of Rosmarinus officinalis Leaf Extract on KB Cell Lines |
Sesamin | 📋 | ✍ | | | 38679210 | Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo |
Spikenard | 📋 | ✍ | ⛔ | | 35561851 | Terpenoids from Nardostachys jatamansi and their cytotoxic activity against human pancreatic cancer cell lines |
Theaflavins | 📋 | ✍ | | | 37549726 | Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling |
Vitamins | 📋 | | | | 37964614 | Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias |
Avocado | 📋 | ✍ | ⛔ | | 38407926 | Cytotoxic and Antitumoral Effects of Methanolic Extracts of Avocado Fruit Mesocarp in Colorectal Cancer Cell Line HT29 |
DIM | 📋 | ✍ | ⛔ | | 37793204 | 3, 3'-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing "glycolysis-lactate-STAT3″ and TIP60 signals-mediated Treg differentiation |
Galangal | 📋 | ✍ | ⛔ | | 37664921 | Exploring the Underlying Mechanism of Alpinia officinarum Hance Ameliorating Diabetic Gastroparesis through Combining Network Pharmacology, Molecular Docking, and in Vivo Experimental Verification |
Geraniol | 📋 | | | | 36849063 | Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Geraniol alleviates acute liver failure |
Krill Oil | 📋 | ✍ | ⛔ | | 38672464 | Krill Oil and Its Bioactive Components as a Potential Therapy for Inflammatory Bowel Disease: Insights from In Vivo and In Vitro Studies |
Magnolia | 📋 | ✍ | ⛔ | | 37393026 | Identification of the therapeutic effect and molecular mechanism of Coptis chinensis Franch. and Magnolia officinalis var. biloba on chronic gastritis |
Quinoa | 📋 | | ⛔ | | 38226896 | A quinoa peptide protects impaired mucus barriers in colitis mice by inhibiting NF-κB-TRPV1 signaling and regulating the gut microbiota |
Spermidine | 📋 | | | | 38695904 | Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine |
Tomato | 📋 | | ⛔ | | 38398886 | Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study |
Yogurt | 📋 | | ⛔ | | 38628190 | Probiotic yogurt regulates gut microbiota homeostasis and alleviates hepatic steatosis and liver injury induced by high-fat diet in golden hamsters |
Artichoke | 📋 | ✍ | ⛔ | | 37891925 | Evaluation of the Protective and Regenerative Properties of Commercially Available Artichoke Leaf Powder Extract on Plasma and Liver Oxidative Stress Parameters |
Balloon Flower | 📋 | ✍ | ⛔ | | 38542804 | Platycodi Radix Extract Prevents Hepatic Steatosis by Enhancing Bile Acid Synthesis in a High-Fat Diet-Induced Fatty Liver Mouse Model |
Beta-Lapachone | 📋 | | | | 38218311 | β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway |
Bitter Melon | 📋 | ✍ | ⛔ | | 35527657 | Momordica charantia polysaccharides alleviate diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and barrier via NF-κB pathway |
Black Tea Polyphenols | 📋 | | | | 36008552 | Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway |
Cyanidin | 📋 | ✍ | | | 36552590 | Cyanidin Alleviated CCl4-Induced Acute Liver Injury by Regulating the Nrf2 and NF-κB Signaling Pathways |
Diallyl Trisulfide | 📋 | | | | 37964870 | Prediction of the mechanism for the combination of diallyl trisulfide and cisplatin against gastric cancer: a network pharmacology study and pharmacological evaluation |
Fenugreek | 📋 | ✍ | ⛔ | | 37336337 | Isolation of alkaloidal and glycosidal fractions from leaves of Trigonella foenum-graecum L. cv. Desi indigenous to Pakistan for antiprostaglandin evaluation as substitute of nonsteroidal anti-inflammatory drugs |
Fig | 📋 | | ⛔ | | 35427822 | Autophagy is involved in Ficus carica fruit extract-induced anti-tumor effects on pancreatic cancer |
Ginkgolic Acid | 📋 | | | | 38387271 | Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect |
Gotu Kola | 📋 | ✍ | ⛔ | | 37576314 | A herb mixture to ameliorate non-alcoholic fatty liver in rats fed a high-fat diet |
Kimchi | 📋 | | ⛔ | | 38367426 | Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice |
L-Citrulline | 📋 | ✍ | ⛔ | | 38306371 | Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion |
Lemon Balm | 📋 | ✍ | ⛔ | | 38303002 | Melissa officinalis extract palliates redox imbalance and inflammation associated with hyperthyroidism-induced liver damage by regulating Nrf-2/ Keap-1 gene expression in γ-irradiated rats |
Lion's Mane Mushrooms | 📋 | ✍ | ⛔ | | 38556226 | Polysaccharides from an edible mushroom, Hericium erinaceus, alleviate ulcerative colitis in mice by inhibiting the NLRP3 inflammasomes and reestablish intestinal homeostasis |
Lutein | 📋 | ✍ | ⛔ | | 36770846 | Lutein Induces Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer AGS Cells via NADPH Oxidase Activation |
Lychee | 📋 | | ⛔ | | 36774343 | Litchi procyanidins inhibit colon cancer proliferation and metastasis by triggering gut-lung axis immunotherapy |
Nimbolide | 📋 | | | | 38561609 | The Neem Limonoid Nimbolide Modulates Key Components of the DNA Damage Response Signalling in Cellular and Animal Models of Oral Squamous Cell Carcinoma |
Nuciferine | 📋 | | | | 37833979 | Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway |
Oleanolic Acid | 📋 | | | | 38387275 | Oleanolic acid inhibits hypoxic tumor-derived exosomes-induced premetastatic niche formation in hepatocellular carcinoma by targeting ERK1/2-NFκB signaling |
Oolong Tea | 📋 | | ⛔ | | 38268839 | Aged oolong tea alleviates dextran sulfate sodium-induced colitis in mice by modulating the gut microbiota and its metabolites |
Proanthocyanidins | 📋 | | | | 37719964 | Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway |
PUFA | 📋 | | | | 38388563 | Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth |
Safranal | 📋 | | | | 35740022 | Molecular Mechanisms behind Safranal's Toxicity to HepG2 Cells from Dual Omics |
Vitexin | 📋 | | | | 37676484 | Regulation of gut microbiota and alleviation of DSS-induced colitis by vitexin |
Whey Protein | 📋 | ✍ | ⛔ | | 38573884 | Whey protein supplementation reduced the liver damage scores of rats fed with a high fat-high fructose diet |
Ashwagandha | 📋 | ✍ | ⛔ | | 38674831 | In Vitro Inhibition of Colorectal Cancer Gene Targets by Withania somnifera L. Methanolic Extracts: A Focus on Specific Genome Regulation |
Bitter Orange | 📋 | ✍ | ⛔ | | 36425596 | Bioactivity guided isolation and identification of phenolic compounds from Citrus aurantium L. with anti-colorectal cancer cells activity by UHPLC-Q-TOF/MS |
Blackberry | 📋 | | ⛔ | | 38675162 | Anti- Helicobacter pylori Biofilm Extracts from Rubus idaeus and Rubus occidentalis |
Chrysanthemum | 📋 | ✍ | ⛔ | | 37099836 | Effects and mechanism of action of Chrysanthemum morifolium (Jinsi Huangju) on hyperlipidemia and non-alcoholic fatty liver disease |
Fennel | 📋 | ✍ | ⛔ | | 35802574 | The effect of a fennel seed extract on the STAT signaling and intestinal barrier function |
Haritaki | 📋 | ✍ | ⛔ | | 38152693 | Ethyl acetate extract of Terminalia chebula alleviates DSS-induced ulcerative colitis in C57BL/6 mice |
Linoleic Acid | 📋 | ✍ | ⛔ | | 36263307 | Association between dietary intake of fatty acids and colorectal cancer, a case-control study |
Myrtle | 📋 | ✍ | ⛔ | | 35056895 | Beneficial Effects of Laurel ( Laurus nobilis L.) and Myrtle ( Myrtus communis L.) Extract on Rat Health |
Persimmon | 📋 | | ⛔ | | 35766964 | Persimmon Water Extract Suppresses Hepatic Lipotoxicity by Regulating Lipid Metabolites |
Phosphatidylcholine | 📋 | ✍ | ⛔ | | 38262589 | Oral supplementation of phosphatidylcholine attenuates the onset of a diet-induced metabolic dysfunction-associated steatohepatitis in female C57BL/6J mice |
Plum | 📋 | | ⛔ | | 35971232 | Prune juice containing sorbitol, pectin, and polyphenol ameliorates subjective complaints and hard feces while normalizing stool in chronic constipation: A randomized placebo-controlled trial |
Pomegranate Seed extract | 📋 | | ⛔ | | 38065332 | Pomegranate Seed Oil Mitigates Liver and Kidney Damage in an Experimental Colitis Model: Modulation of NF-κB Activation and Apoptosis |
Sage | 📋 | ✍ | ⛔ | | 36034079 | Salvia officinalis leaf extracts protect against acute colitis in rats |
Sesamol | 📋 | | | | 37976698 | Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage |
Sweet Potato | 📋 | | ⛔ | | 36505243 | Sweet potato extract alleviates high-fat-diet-induced obesity in C57BL/6J mice, but not by inhibiting pancreatic lipases |
Tea Polyphenols | 📋 | | | | 38307369 | Study on the relationship between tea polyphenols alleviating osteoporosis and the changes of microorganism-metabolite-intestinal barrier |
Theabrownins | 📋 | | | | 38642504 | Theabrownin from Qingzhuan tea prevents high-fat diet-induced MASLD via regulating intestinal microbiota |
Biochanin A | 📋 | | | | 38648921 | Biochanin a ameliorates DSS-induced ulcerative colitis by improving colonic barrier function and protects against the development of spontaneous colitis in the Muc2 deficient mice |
Buckwheat | 📋 | | ⛔ | | 36615659 | Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health |
Cardamonin | 📋 | | | | 37302524 | A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases |
Carnosol | 📋 | | | | 37386230 | Downregulation of SODD mediates carnosol-induced reduction in cell proliferation in esophageal adenocarcinoma cells |
Carrot | 📋 | | ⛔ | | 37764365 | Effect of Extraction Methods on the Antioxidant Potential and Cytotoxicity of the Combined Ethanolic Extracts of Daucus carota L., Beta vulgaris L., Phyllanthus emblica L. and Lycopersicon esculentum against Gastric Adenocarcinoma Cells |
Chaga Mushrooms | 📋 | ✍ | ⛔ | | 38720012 | Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism |
Cherry | 📋 | | ⛔ | | 37266135 | Phytochemical screening of Prunus avium for its antioxidative and anti-mutagenic potential against DMBA-induced hepatocarcinogenesis |
Choline | 📋 | ✍ | ⛔ | | 38711145 | Dietary choline intake and health outcomes in U.S. adults: exploring the impact on cardiovascular disease, cancer prevalence, and all-cause mortality |
Coumaric acid | 📋 | | | | 37183931 | The protective effect of p-Coumaric acid on hepatic injury caused by particulate matter in the rat and determining the role of long noncoding RNAs MEG3 and HOTAIR |
Date | 📋 | | ⛔ | | 36386915 | Potential bioactivity of Phoenix dactylifera fruits, leaves, and seeds against prostate and pancreatic cancer cells |
Fennel Essential Oil | 📋 | ✍ | ⛔ | | 34725578 | Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb®) in Relieving Constipation |
Ganoderic Acid | 📋 | | | | 38322557 | Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning |
Genipin | 📋 | | | | 38175425 | Genipin inhibits proliferation of gastric cancer cells by inducing ferroptosis: an integrated study of network pharmacology and bioinformatics study |
Hyaluronic Acid | 📋 | ✍ | ⛔ | | 37920632 | Hyaluronic Acid: Exploring Its Versatile Applications in Dentistry |
Hyperoside | 📋 | | | | 37923159 | Hyperoside attenuates carbon tetrachloride-induced hepatic fibrosis via the poly(ADP-ribose)polymerase-1-high mobility group protein 1 pathway |
Mango | 📋 | | ⛔ | | 38682277 | Colon-available mango (poly)phenols exhibit mitigating effects on the intestinal barrier function in human intestinal cell monolayers under inflammatory conditions |
Mastic | 📋 | ✍ | ⛔ | | 37147480 | Mastic (Pistacia lentiscus) gum and oral health: a state-of-the-art review of the literature |
Neem | 📋 | ✍ | | | 38585261 | The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study |
Neferine | 📋 | | | | 37031639 | Neferine ameliorates nonalcoholic steatohepatitis through regulating AMPK pathway |
Olive Polyphenols | 📋 | | | | 38528541 | Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis |
Postbiotics | 📋 | | | | 38596883 | Postbiotic Administration Ameliorates Colitis and Inflammation in Rats Possibly through Gut Microbiota Modulation |
Red Yeast Rice | 📋 | ✍ | ⛔ | | 37358849 | Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality |
SAMe | 📋 | ✍ | ⛔ | | 37634598 | Treatment with S-adenosylmethionine ameliorates irinotecan-induced intestinal barrier dysfunction and intestinal microbial disorder in mice |
Syringic Acid | 📋 | | | | 38644776 | Syringic acid guards against indomethacin-induced gastric ulcer by alleviating inflammation, oxidative stress and apoptosis |
Tannic Acid | 📋 | ✍ | ⛔ | | 37642057 | Triggering of Endoplasmic Reticulum Stress by Tannic Acid Inhibits the Proliferation and Migration of Colorectal Cancer Cells |
Vitamin K2 | 📋 | ✍ | ⛔ | | 38321064 | Vitamin K2 protects mice against non-alcoholic fatty liver disease induced by high-fat diet |
Arjuna | 📋 | ✍ | ⛔ | | 37850546 | Optimizing the extraction of polyphenols from the bark of Terminalia arjuna and an in-silico investigation on its activity in colorectal cancer |
Asafoetida | 📋 | ✍ | ⛔ | | 38138502 | Antitumor and Phytochemical Properties of Ferula assa-foetida L. Oleo-Gum-Resin against HT-29 Colorectal Cancer Cells In Vitro and in a Xenograft Mouse Model |
Asiaticoside | 📋 | | | | 38384110 | Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology |
Asparagus | 📋 | | ⛔ | | 36596190 | Nutritional composition of green asparagus (Asparagus officinalis L.), edible part and by-products, and assessment of their effect on the growth of human gut-associated bacteria |
Astragalin | 📋 | | | | 37088763 | [Effects of Astragalin on apoptosis of undifferentiated gastric cancer cells] |
Beets | 📋 | ✍ | ⛔ | | 37764365 | Effect of Extraction Methods on the Antioxidant Potential and Cytotoxicity of the Combined Ethanolic Extracts of Daucus carota L., Beta vulgaris L., Phyllanthus emblica L. and Lycopersicon esculentum against Gastric Adenocarcinoma Cells |
Berries | 📋 | | | | 38067418 | In Vitro Inhibitory Potential of Different Anthocyanin-Rich Berry Extracts in Murine CT26 Colon Cancer Cells |
Bilobalide | 📋 | | | | 38125341 | Bilobalide attenuates lipopolysaccharide‑induced HepG2 cell injury by inhibiting TLR4‑NF‑κB signaling via the PI3K/Akt pathway |
Black Pepper | 📋 | ✍ | ⛔ | | 37765133 | Piper nigrum Extract Inhibits the Growth of Human Colorectal Cancer HT-29 Cells by Inducing p53-Mediated Apoptosis |
Boric Acid | 📋 | ✍ | ⛔ | | 37770673 | Boric Acid (Boron) Attenuates AOM-Induced Colorectal Cancer in Rats by Augmentation of Apoptotic and Antioxidant Mechanisms |
Caffeic Acid | 📋 | ✍ | ⛔ | | 35269912 | Natural Compounds for Counteracting Nonalcoholic Fatty Liver Disease (NAFLD): Advantages and Limitations of the Suggested Candidates |
CAPE | 📋 | | | | 38379263 | Caffeic acid phenethyl ester mediates apoptosis in serum-starved HT29 colon cancer cells through modulation of heat shock proteins and MAPK pathways |
Cardamom | 📋 | ✍ | ⛔ | | 37779590 | Protective effects of cardamom aqueous extract against tamoxifen-induced pancreatic injury in female rats |
Citrus Fruits | 📋 | | ⛔ | | 36370925 | Citrus peel ameliorates mucus barrier damage in HFD-fed mice |
Cornus | 📋 | | | | 37716032 | Cornuside improves murine autoimmune hepatitis through inhibition of inflammatory responses |
Delphinidin | 📋 | | | | 36179123 | Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells |
Eleuthero | 📋 | ✍ | ⛔ | | 37467688 | Syringin alleviates hepatic fibrosis by enhancing autophagic flux and attenuating ER stress-TRIB3/SMAD3 in diabetic mice |
Fo-Ti Root | 📋 | ✍ | ⛔ | | 38284886 | Prepared radix polygoni multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition |
Isoquercitrin | 📋 | | | | 38084034 | Isoquercitrin alleviates lipopolysaccharide-induced intestinal mucosal barrier damage in mice by regulating TLR4/MyD88/NF-κB signaling pathway and intestinal flora |
Jasmine | 📋 | | ⛔ | | 36558518 | Cold-Brewed Jasmine Tea Attenuates High-Fat Diet-Induced Obesity and Gut Microbial Dysbiosis |
Kombucha | 📋 | ✍ | ⛔ | | 38149073 | Evaluation of the Efficacy of Kombucha-Based Drink Enriched with Inulin and Vitamins for the Management of Constipation-Predominant Irritable Bowel Syndrome in Females: A Randomized Pilot Study |
L-Carnosine | 📋 | ✍ | ⛔ | | 38348714 | Quantitative proteomics study of carnosine effect in an animal model of Western diet-induced nonalcoholic fatty liver disease |
Lavender Essential Oil | 📋 | ✍ | ⛔ | | 36910997 | Efficacy of Aromatherapy for Night Crying in Infants with Infantile Colic: A Double-Blind Randomized Controlled Trial |
Lotus | 📋 | | ⛔ | | 38526570 | Lotus Leaf Extract Alleviates Lipopolysaccharide-Induced Intestinal Injury in Mice by Regulating Oxidative Stress and Inflammation |
Malvidin | 📋 | | | | 36562464 | Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium |
Osmanthus | 📋 | ✍ | ⛔ | | 38380575 | Ethyl acetate fraction of Osmanthus fragrans var. aurantiacus and its triterpenoids suppress proliferation and survival of colorectal cancer cells by inhibiting NF-κB and COX2 |
Peanut | 📋 | | ⛔ | | 36187387 | Inverse relations between Helicobacter pylori infection and risk of esophageal precancerous lesions in drinkers and peanut consumption |
Quercitrin | 📋 | | | | 35337161 | Quercetin and Quercitrin from Agrimonia pilosa Ledeb Inhibit the Migration and Invasion of Colon Cancer Cells through the JNK Signaling Pathway |
Seaweeds | 📋 | | ⛔ | | 37201636 | Seaweed polysaccharides treatment alleviates injury of inflammatory responses and gut barrier in LPS-induced mice |
Soy | 📋 | ✍ | ⛔ | | 36777798 | Association between soy products, fruits, vegetables, and dairy products and gastric cancer risk in Helicobacter pylori-infected subjects: a case-control study in Korea |
Stigmasterol | 📋 | | | | 38678948 | Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma |
Vegetables | 📋 | | | | 38374605 | Effect of Vegetable Consumption on Risk of Gastric Cancer: A Systematic Review and Multi-level Meta-analysis of Prospective Studies |
Wine | 📋 | | ⛔ | | 37712265 | [Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis] |
Zeaxanthin | 📋 | ✍ | ⛔ | | 36690321 | Zeaxanthin prevents ferroptosis by promoting mitochondrial function and inhibiting the p53 pathway in free fatty acid-induced HepG2 cells |
Anethole | 📋 | | | | 37242484 | Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways |
Anise | 📋 | ✍ | ⛔ | | 38103135 | Anise (Pimpinella anisum L.) attenuates azoxymethane-induced colorectal cancer by antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats |
Anthocyanidins | 📋 | | | | 36516693 | Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK- and NF-kB dependent manner: Results from the ATTACH-study a randomized, controlled, crossover trial in healthy subjects |
Apricot Kernels | 📋 | ✍ | ⛔ | | 34146630 | Phytochemical characterization and biological activity of apricot kernels' extract in yeast-cell based tests and hepatocellular and colorectal carcinoma cell lines |
Bay Leaf | 📋 | | ⛔ | | 38628202 | Anti-inflammatory effects of bay laurel (Laurus nobilis L.) towards the gut microbiome in dextran sodium sulfate induced colitis animal models |
Chondroitin | 📋 | ✍ | ⛔ | | 37870229 | Effect of Oral Chondroitin Sulfate Supplementation on Acute Brain Injury in a Murine Necrotizing Enterocolitis Model |
Citral | 📋 | | | | 38132361 | Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries |
Clove | 📋 | | ⛔ | | 37608671 | Therapeutic Potential of Syzygium aromaticum in Gut Dysbiosis via TMAO Associated Diabetic Cardiomyopathy |
Clove Essential Oil | 📋 | | ⛔ | | 38666995 | Efficacy and Synergistic Potential of Cinnamon (Cinnamomum zeylanicum) and Clove (Syzygium aromaticum L. Merr. & Perry) Essential Oils to Control Food-Borne Pathogens in Fresh-Cut Fruits |
Coconut Oil | 📋 | | ⛔ | | 37905950 | Virgin Coconut Oil Alleviates Dextran Sulphate-Induced Inflammatory Bowel Disease and Modulates Inflammation and Immune Response in Mice |
Coriander | 📋 | | ⛔ | | 37518878 | Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury |
D-Limonene | 📋 | ✍ | ⛔ | | 38540754 | Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway |
Diallyl Disulfide | 📋 | | | | 38642008 | Diallyl disulfide antagonizes DJ-1 mediated proliferation, epithelial-mesenchymal transition, and chemoresistance in gastric cancer cells |
Egg | 📋 | | ⛔ | | 38037542 | Egg Yolk Lipids Alleviated Dextran Sulfate Sodium-Induced Colitis by Inhibiting NLRP3 Inflammasome and Regulating Gut Microbiota |
Fish | 📋 | | ⛔ | | 37889850 | Associations of Fish and Fish Oil Consumption With Incident Inflammatory Bowel Disease: A Population-Based Prospective Cohort Study |
Ginger Essential Oil | 📋 | ✍ | | | 37210385 | Ginger essential oil and citral ameliorates atherosclerosis in ApoE-/- mice by modulating trimethylamine-N-oxide and gut microbiota |
Jujube | 📋 | | ⛔ | | 38600887 | Polyphenol Extracts from Ziziphus jujuba Mill. "Junzao" Attenuates Ulcerative Colitis by Inhibiting the NLRP3 and MAPKs Signaling Pathways and Regulating Gut Microbiota Homeostasis in Mice |
Lemon | 📋 | | ⛔ | | 38204757 | Citrus limon (L.) Osbeck Fruit Peel Extract Attenuates Carbon Tetrachloride-Induced Hepatocarcinogenesis in Sprague-Dawley Rats |
Linalool | 📋 | | ⛔ | | 38240782 | Effects of linalool on postoperative peritoneal adhesions in rats |
Marjoram | 📋 | | ⛔ | | 38420828 | Calcium Channel Inhibitory Effect of Marjoram ( Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity |
Modified Citrus Pectin | 📋 | ✍ | ⛔ | | 34789268 | MCP mediated active targeting calcium phosphate hybrid nanoparticles for the treatment of orthotopic drug-resistant colon cancer |
Morin | 📋 | | | | 37802874 | [Morin induces autophagy and apoptosis in hepatocellular carcinoma cells through Akt/mTOR/STAT3 pathway] |
Morusin | 📋 | | | | 38432611 | Morusin suppresses the stemness characteristics of gastric cancer cells induced by hypoxic microenvironment through inhibition of HIF-1α accumulation |
Mushrooms | 📋 | | ⛔ | | 38154526 | Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-β1/Smads pathways |
Noni | 📋 | | ⛔ | | 38144717 | Constituent analysis, laxative activity, and toxicological evaluation of methanol extract of noni fruit ( Morinda citrifolia L., Rubiaceae) |
Onion | 📋 | ✍ | ⛔ | | 37659760 | Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories |
Pistachio | 📋 | ✍ | ⛔ | | 32801830 | The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis |
Protein | 📋 | ✍ | ⛔ | | 37407836 | Associations of intakes of total protein, protein from dairy sources, and dietary calcium with risks of colorectal, breast, and prostate cancer: a prospective analysis in UK Biobank |
Rehmannia | 📋 | ✍ | ⛔ | | 36908905 | Oligosaccharides isolated from Rehmannia glutinosa protect LPS-induced intestinal inflammation and barrier injury in mice |
Thyme | 📋 | ✍ | ⛔ | | 38271407 | Anti H. pylori, anti-secretory and gastroprotective effects of Thymus vulgaris on ethanol-induced gastric ulcer in Sprague Dawley rats |
Tribulus Terrestris | 📋 | ✍ | ⛔ | | 38309487 | In-depth investigation of the therapeutic effect of Tribulus terrestris L. on type 2 diabetes based on intestinal microbiota and feces metabolomics |
Barley | 📋 | ✍ | ⛔ | | 36495148 | Barley Grass Juice Attenuates Hydrodynamic Transfection-Induced HCC Initiation in Mice |
Basil | 📋 | ✍ | ⛔ | | 38058645 | Ameliorating effects of Acacia arabica and Ocimum basilicum on acetic acid-induced ulcerative colitis model through mitigation of inflammation and oxidative stress |
Cabbage | 📋 | | ⛔ | | 38337674 | Anti-Inflammatory Effect of Chestnut Honey and Cabbage Mixtures Alleviates Gastric Mucosal Damage |
Caraway Essential Oil | 📋 | | ⛔ | | 32711288 | Menthacarin attenuates experimental colitis |
Catalpol | 📋 | | | | 37979473 | Catapol attenuates the aseptic inflammatory response to hepatic I/R injury in vivo and in vitro by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway via the microRNA-410-3p |
Chicory | 📋 | ✍ | ⛔ | | 38507851 | Phenolic acids from Chicory roots ameliorate dextran sulfate sodium-induced colitis in mice by targeting TRP signaling pathways and the gut microbiota |
Coconut | 📋 | | ⛔ | | 38278200 | Coconut water induces clinical remission in mild to moderate ulcerative colitis: double-blind placebo controlled trial |
Fish Collagen | 📋 | ✍ | ⛔ | | 37367668 | Fish-Derived Protein Hydrolysates Increase Insulin Sensitivity and Alter Intestinal Microbiome in High-Fat-Induced Obese Mice |
Garlic Oil | 📋 | | ⛔ | | 35959265 | Garlic oil alleviates high triglyceride levels in alcohol-exposed rats by inhibiting liver oxidative stress and regulating the intestinal barrier and intestinal flora |
Geraniin | 📋 | | | | 38530797 | Geraniin Alleviates Inflammation in Caco-2 Cells and Dextran Sulfate Sodium-Induced Colitis Mice by Targeting IL-1β |
Ginkgetin | 📋 | | | | 38217097 | Ginkgetin exhibits antifibrotic effects by inducing hepatic stellate cell apoptosis via STAT1 activation |
Glabridin | 📋 | | | | 37714449 | Glabridin ameliorates intracellular events caused by palmitic acid and alcohol in mouse hepatocytes and fast food diet and alcohol -induced steatohepatitis and fibrosis in C57BL/6J mice model |
Glucosamine | 📋 | ✍ | ⛔ | | 37836761 | Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism |
Grapefruit extract | 📋 | ✍ | ⛔ | | 35043844 | Explore the antiproliferative phytocompounds from ethanolic extracts of Citrus paradisi against liver cancer cell line by chemical analysis using TLC and FT-IR spectroscopy |
Guggulsterone | 📋 | | | | 36635928 | Guggulsterone promotes nasopharyngeal carcinoma cells exosomal circFIP1L1 to mediate miR-125a-5p/VEGFA affecting tumor angiogenesis |
Honeysuckle | 📋 | | ⛔ | | 38307354 | Study on the ameliorative effect of honeysuckle on DSS-induced ulcerative colitis in mice |
Irisin | 📋 | | | | 38671861 | The Role of the Myokine Irisin in the Protection and Carcinogenesis of the Gastrointestinal Tract |
Knotweed | 📋 | ✍ | ⛔ | | 36683716 | In vivo recognition of bioactive substances of Polygonum multiflorum for protecting mitochondria against metabolic dysfunction-associated fatty liver disease |
Lemon Essential Oil | 📋 | ✍ | ⛔ | | 38132361 | Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries |
Loquat | 📋 | ✍ | ⛔ | | 38608471 | Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis |
Milk | 📋 | | ⛔ | | 38370079 | Consumption of dairy products and odds of ulcerative colitis: An Iranian case-control study |
Nutmeg | 📋 | ✍ | ⛔ | | 35565666 | Myristica fragrans Extract Regulates Gut Microbes and Metabolites to Attenuate Hepatic Inflammation and Lipid Metabolism Disorders via the AhR-FAS and NF-κB Signaling Pathways in Mice with Non-Alcoholic Fatty Liver Disease |
Okra | 📋 | | ⛔ | | 38004214 | Chemopreventive Effects of Polysaccharides and Flavonoids from Okra Flowers in Azomethane/Dextran Sulfate Sodium-Induced Murine Colitis-Associated Cancer |
Oleic Acid | 📋 | | ⛔ | | 37253404 | Oleic acid improves hepatic lipotoxicity injury by alleviating autophagy dysfunction |
Soy Isoflavones | 📋 | ✍ | ⛔ | | 37375574 | The Role of Choline, Soy Isoflavones, and Probiotics as Adjuvant Treatments in the Prevention and Management of NAFLD in Postmenopausal Women |
Valerian Root | 📋 | ✍ | ⛔ | | 35863616 | Antidiarrheal activity of the extracts of Valeriana jatamansi Jones on castor oil-induced diarrhea mouse by regulating multiple signal pathways |
White Tea | 📋 | | ⛔ | | 38628196 | Investigation of the effects of white tea on liver fibrosis: An experimental animal model |
Almond | 📋 | | ⛔ | | 34057922 | Almond protects the liver in coronary artery disease: A randomized controlled clinical trial |
Banana | 📋 | | ⛔ | | 36692306 | Role of cooked green banana in home management of acute diarrhea in under-5 children |
Basil Essential Oil | 📋 | ✍ | ⛔ | | 32641615 | Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model With Special Reference to Gut Microbiota |
Bee Pollen | 📋 | ✍ | ⛔ | | 37330827 | Integrated microbiomic and metabolomic analyses reveal the mechanisms by which bee pollen and royal jelly lipid extracts ameliorate colitis in mice |
Bile Salts | 📋 | | | | 38680685 | The role of bile acids in human aging |
Chia Seeds | 📋 | | ⛔ | | 37689868 | Chia (Salvia hispanica L.) flour modulates the intestinal microbiota in Wistar rats fed a high-fat and high-fructose diet |
Citicoline | 📋 | ✍ | ⛔ | | 37291355 | Valuable effects of lactobacillus and citicoline on steatohepatitis: role of Nrf2/HO-1 and gut microbiota |
Colostrum | 📋 | ✍ | ⛔ | | 38409162 | Therapeutics effects of bovine colostrum applications on gastrointestinal diseases: a systematic review |
Copper | 📋 | ✍ | ⛔ | | 38579045 | The association between intakes of dietary trace minerals and gallstone disease: A cross-sectional study from National Health and Nutrition Examination Survey 2017 to 2018 |
Dairy | 📋 | | | | 37650016 | Influence of dairy products consumption on oral cancer risk: A meta-analysis |
Echinacoside | 📋 | | | | 38461536 | Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma |
Elderberry | 📋 | ✍ | ⛔ | | 37895164 | Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo |
Eucalyptus | 📋 | ✍ | ⛔ | | 35284740 | Cheminformatics Application in the Phytochemical and Biological Study of Eucalyptus globulus L. Bark as a Potential Hepatoprotective Drug |
Eucommia | 📋 | ✍ | ⛔ | | 36982954 | Eucommia Polysaccharides Ameliorate Aging-Associated Gut Dysbiosis: A Potential Mechanism for Life Extension in Drosophila |
Flaxseed Oil | 📋 | ✍ | ⛔ | | 37960203 | Flaxseed Oil ( Linum usitatissimum) Prevents Cognitive and Motor Damage in Rats with Hyperammonemia |
Goat Milk | 📋 | | ⛔ | | 37830350 | Fermented Goat's Milk Contributes to the Recovery of Iron Deficiency Anemia via Modulation of the Gut Microbiome |
Haskap | 📋 | | | | 37764808 | Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway |
Hazelnut | 📋 | | ⛔ | | 37200761 | Study of the Apoptotic Impacts of Hazelnut Oil on the Colorectal Cancer Cell Line |
Holy Basil | 📋 | ✍ | ⛔ | | 34440988 | An In Vitro Anti-Cancer Activity of Ocimum tenuiflorum Essential Oil by Inducing Apoptosis in Human Gastric Cancer Cell Line |
Hypericin | 📋 | | | | 34089613 | Hypericin-mediated photodynamic therapy enhances gemcitabine induced Capan-2 cell apoptosis via inhibiting NADPH level |
L-Methionine | 📋 | ✍ | ⛔ | | 38367245 | l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma |
Laminaria | 📋 | ✍ | ⛔ | | 36355026 | Laminaria japonica Peptides Suppress Liver Cancer by Inducing Apoptosis: Possible Signaling Pathways and Mechanism |
Ligustilide | 📋 | | | | 35494068 | Z-Ligustilide Induces c-Myc-Dependent Apoptosis via Activation of ER-Stress Signaling in Hypoxic Oral Cancer Cells |
Liquiritigenin | 📋 | | | | 37455324 | Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K/AKT pathway |
Liquiritin | 📋 | | | | 36008890 | Liquiritin alleviates alpha-naphthylisothiocyanate-induced intrahepatic cholestasis through the Sirt1/FXR/Nrf2 pathway |
Lupeol | 📋 | | | | 35486494 | Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF-κB pathway |
Marigold | 📋 | ✍ | ⛔ | | 32039173 | Marigold Supercritical Extract as Potential Co-adjuvant in Pancreatic Cancer: The Energetic Catastrophe Induced via BMP8B Ends Up With Autophagy-Induced Cell Death |
Millet | 📋 | | | | 36638159 | Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake |
Minerals | 📋 | | | | 37764853 | The Effect of Polyphenols, Minerals, Fibers, and Fruits on Irritable Bowel Syndrome: A Systematic Review |
Nicotinamide | 📋 | ✍ | ⛔ | | 33870623 | Nicotinamide Protects Against Diet-Induced Body Weight Gain, Increases Energy Expenditure and Induces White Adipose Tissue Beiging |
Oregano Essential Oil | 📋 | ✍ | ⛔ | | 36903396 | Savory, Oregano and Thyme Essential Oil Mixture (HerbELICO®) Counteracts Helicobacter pylori |
Oyster | 📋 | | ⛔ | | 36965559 | Oyster polysaccharides relieve DSS-induced colitis via anti-inflammatory and maintaining the physiological hypoxia |
Oyster Mushrooms | 📋 | | ⛔ | | 36374945 | Anticancer Properties of Selenium-Enriched Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), in Colon Cancer In Vitro |
Papaya | 📋 | ✍ | ⛔ | | 38388061 | Ripe papaya pectins inhibit the proliferation of colon cancer spheroids and the formation of chemically induced aberrant crypts in rats colons |
Pau d'Arco | 📋 | ✍ | ⛔ | | 28877696 | Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb.) water extract prevents DSS-induced colitis in mice by up-regulating type II T helper immune responses |
Pineapple | 📋 | ✍ | ⛔ | | 34946738 | Pineapple Leaf Phenols Attenuate DSS-Induced Colitis in Mice and Inhibit Inflammatory Damage by Targeting the NF-κB Pathway |
Potato | 📋 | | ⛔ | | 38253109 | Dietary purple potato supplement attenuates DSS-induced colitis in mice: Impact on mitochondrial function |
PQQ | 📋 | ✍ | ⛔ | | 34227919 | Pyrroloquinoline quinone (PQQ) alleviated sepsis-induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression |
Prickly Pear | 📋 | | ⛔ | | 38474715 | A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of Opuntia ficus- indica Prebiotic Supplementation in Subjects with Gut Dysbiosis |
Radish | 📋 | | ⛔ | | 36501112 | Hepatoprotective Effects of Radish ( Raphanus sativus L.) on Acetaminophen-Induced Liver Damage via Inhibiting Oxidative Stress and Apoptosis |
Rice | 📋 | | ⛔ | | 36615905 | Red Rice Bran Extract Alleviates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease and Dyslipidemia in Mice |
Sesame | 📋 | ✍ | ⛔ | | 37781062 | Antioxidant activities of thermally treated Sesamum indicum L. leaf extracts and their inhibitory effects against growth and metastatic properties of human colon cancer cells |
Soy Protein | 📋 | ✍ | ⛔ | | 38075211 | Feeding soy protein concentrates with low or high isoflavone decreases liver inflammation by reducing lipopolysaccharide translocation |
Telmisartan | 📋 | | ⛔ | | 37831115 | Telmisartan and candesartan promote browning of white adipose tissue and reverse fatty liver changes in high fat diet fed male albino rats |
Thyme Essential Oil | 📋 | | ⛔ | | 38034947 | Comparison of the virucidal efficacy of essential oils (cinnamon, clove, and thyme) against hepatitis A virus in suspension and on food-contact surfaces |
Trans-Resveratrol | 📋 | | | | 36191991 | The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma |
Vitamin B1 | 📋 | ✍ | ⛔ | | 37720374 | Association of vitamin B1 with cardiovascular diseases, all-cause and cardiovascular mortality in US adults |
Vitamin K | 📋 | ✍ | ⛔ | | 37049518 | Low Vitamin K and Vitamin D Dietary Intake in Patients with Inflammatory Bowel Diseases |
Yam | 📋 | | | | 37545095 | Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways |
Apple Vinegar | 📋 | ✍ | ⛔ | | 36564752 | Effect of apple vinegar on folliculogenesis and ovarian kisspeptin in a high-fat diet-induced nonalcoholic fatty liver disease in rat |
Bamboo | 📋 | ✍ | ⛔ | | 38334213 | The alleviative effects comparison of four flavonoids from bamboo leaves on ulcerative colitis in an Alzheimer mouse model |
Chicoric Acid | 📋 | | | | 38485738 | Chicoric Acid Alleviates Colitis via Targeting the Gut Microbiota Accompanied by Maintaining Intestinal Barrier Integrity and Inhibiting Inflammatory Responses |
Chitosan | 📋 | ✍ | ⛔ | | 37749921 | Pharmacodynamic study of chitosan in combination with salvianolic acid B in the treatment of CC14 -induced liver fibrosis in mice |
Costus | 📋 | ✍ | ⛔ | | 37396159 | Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease |
Fermented Foods | 📋 | | ⛔ | | 38163708 | The attenuating effect of fermented soymilk on DSS-induced colitis in mice by suppressing immune response and modulating gut microbiota |
Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 38443203 | The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats |
Grapefruit Essential Oil | 📋 | ✍ | ⛔ | | 32760938 | Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis |
HMB | 📋 | ✍ | ⛔ | | 37739730 | Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study |
Iodine | 📋 | ✍ | ⛔ | | 38305374 | Clinical Efficacy of Different Concentrations of Povidone Iodine in the Management of Peri-Implant Mucositis |
Kale | 📋 | | | | 38094924 | Kale improves bowel movements in constipated women and affects some intestinal microbes and metabolites: a pilot study |
L-Lysine | 📋 | ✍ | ⛔ | | 37648521 | L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model |
Lauric Acid | 📋 | ✍ | | | 38166588 | Lauric acid attenuates hepato-metabolic complications and molecular alterations in high-fat diet-induced Non-alcoholic Fatty Liver Disease in rats |
Lemongrass | 📋 | ✍ | ⛔ | | 38399374 | Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review |
Marjoram Essential Oil | 📋 | | ⛔ | | 35642325 | GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori |
NAD | 📋 | | | | 37371959 | NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies |
Nattokinase | 📋 | ✍ | ⛔ | | 36350434 | Nattokinase enhances the preventive effects of Escherichia coli Nissle 1917 on dextran sulfate sodium-induced colitis in mice |
Neroli Essential Oil | 📋 | ✍ | ⛔ | | 35087623 | Transdermal Administration of Volatile Oil from Citrus aurantium- Rhizoma Atractylodis Macrocephalae Alleviates Constipation in Rats by Altering Host Metabolome and Intestinal Microbiota Composition |
Nuts | 📋 | | ⛔ | | 37242277 | Effect of Nut Consumption on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis |
Omega-6 Fatty Acids | 📋 | ✍ | ⛔ | | 35648467 | Associations of serum n-3 and n-6 polyunsaturated fatty acids with prevalence and incidence of non-alcoholic fatty liver disease |
Orange Essential Oil | 📋 | ✍ | ⛔ | | 38349052 | Effects of the protective and therapeutic effect of yogurt enriched with Citrus sinensis essential oil against ibuprofen-induced gastric ulcer in elderly rats |
Oregano | 📋 | ✍ | ⛔ | | 36284120 | Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy |
Papain | 📋 | ✍ | ⛔ | | 37692988 | Therapeutic effect of bromelain and papain on intestinal injury induced by indomethacin in male rats |
Peach | 📋 | | ⛔ | | 37064951 | Molecular Mechanism of the Therapeutic Effect of Peach Blossom against Constipation: An Exploratory Study Based on Network Pharmacology Analysis and Molecular Docking Verification |
Rose | 📋 | | | | 37797686 | Evaluation of the flavonol-rich fraction of Rosa damascena in an animal model of liver fibrosis by targeting the expression of fibrotic cytokines, antioxidant/oxidant ratio and collagen cross-linking |
Safflower | 📋 | ✍ | ⛔ | | 38593703 | Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function |
Sesame Oil | 📋 | | ⛔ | | 35685535 | Sesame Oil Ameliorates Alanine Aminotransferase, Aspartate Aminotransferase, and Fatty Liver Grade in Women with Nonalcoholic Fatty Liver Disease Undergoing Low-Calorie Diet: A Randomized Double-Blind Controlled Trial |
Spearmint | 📋 | | ⛔ | | 31174376 | Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice |
Spices | 📋 | | | | 38672692 | An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer |
Star Anise | 📋 | ✍ | ⛔ | | 35586683 | Anisi Stellati Fructus, a Significant Traditional Chinese Medicine (TCM) Herb and Its Bioactivity against Gastric Cancer |
Stevia | 📋 | ✍ | ⛔ | | 37237936 | Stevioside Improves Antioxidant Capacity and Intestinal Barrier Function while Attenuating Inflammation and Apoptosis by Regulating the NF-κB/MAPK Pathways in Diquat-Induced Oxidative Stress of IPEC-J2 Cells |
Tea Polysaccharides | 📋 | | | | 37876151 | Amelioration Effects and Regulatory Mechanisms of Different Tea Active Ingredients on DSS-Induced Colitis |
Tetrahydrocurcumin | 📋 | ✍ | | | 30652650 | Tetrahydrocurcumin, Curcumin, and 5-Fluorouracil Effects on Human Esophageal Carcinoma Cells |
Trehalose | 📋 | | ⛔ | | 37581638 | Trehalose-induced SIRT1/AMPK activation regulates SREBP-1c/PPAR-α to alleviate lipid accumulation in aged liver |
Vitamin B Complex | 📋 | | ⛔ | | 38188454 | Role of N-acetylcysteine and vitamin B complex in improving outcomes of corrosive ingestion |
Vitamin B3 | 📋 | ✍ | ⛔ | | 37836412 | Association between Dietary Niacin Intake and Nonalcoholic Fatty Liver Disease: NHANES 2003-2018 |
Vitamin K2 mk-4 | 📋 | ✍ | | | 26314836 | Vitamin K Deficiency Leads to Exacerbation of Murine Dextran Sulfate Sodium-Induced Colitis |
White Fungus | 📋 | | | | 38244583 | Tremella fuciformis polysaccharides induce ferroptosis in Epstein-Barr virus-associated gastric cancer by inactivating NRF2/HO-1 signaling |
White Mushrooms | 📋 | | ⛔ | | 38230753 | Agaricus bisporus polysaccharides ameliorate ulcerative colitis in mice by modulating gut microbiota and its metabolism |
Withanolides | 📋 | | | | 38301983 | Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects |
Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 35456609 | Antispasmodic Effect of Bergamot Essential Oil on Rat Isolated Gut Tissues |
Beta-Alanine | 📋 | ✍ | ⛔ | | 37251265 | Ellagic acid from whole pomegranate fruit reduces liver injury in a rat model of hepatic cholestasis |
Cantaloupe | 📋 | | ⛔ | | 36934555 | Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals |
Capsanthin | 📋 | | | | 36141454 | The Utility of Capsicum annuum L. in Internal Medicine and In Dentistry: A Comprehensive Review |
Cat's Claw | 📋 | ✍ | ⛔ | | 38056537 | Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats |
Celery | 📋 | | ⛔ | | 38355510 | Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-κB/NF-κB p65 signaling pathway: insights from in silico and in vivo investigations |
Cinnamic Acid | 📋 | | | | 38361356 | Cinnamic Acid Ameliorates Acetic Acid-induced Inflammatory Response through Inhibition of TLR-4 in Colitis Rat Model |
Diallyl Sulfide | 📋 | | | | 37209385 | Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells |
Dill | 📋 | | ⛔ | | 34704009 | Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models |
Frankincense Essential Oil | 📋 | | ⛔ | | 37952762 | Basis with RNA-Seq and WGCNA to explore the effect of Frankincense essential oil on dextran sodium sulfate-induced ulcerative colitis through MAPK/NF-κB signaling |
Giloy | 📋 | ✍ | ⛔ | | 38280221 | Traditional uses, hepatoprotective potential, and phytopharmacology of Tinospora cordifolia: a narrative review |
Glycine | 📋 | ✍ | ⛔ | | 33830211 | Dietary Supplementation with Glycine Enhances Intestinal Mucosal Integrity and Ameliorates Inflammation in C57BL/6J Mice with High-Fat Diet-Induced Obesity |
Iron | 📋 | ✍ | ⛔ | | 36742167 | Iron as a therapeutic target in chronic liver disease |
Jackfruit | 📋 | | ⛔ | | 38338941 | Polysaccharide from Artocarpus heterophyllus Lam. (Jackfruit) Pulp Ameliorates Dextran Sodium Sulfate-Induced Enteritis in Rats |
Lavender | 📋 | ✍ | ⛔ | | 35446915 | Cytotoxic effects of Lavandula angustifolia seed extracts on the viability of Huh-7 and Chang liver cells |
Lecithin | 📋 | ✍ | ⛔ | | 37676407 | The Antioxidant and anti-inflammatory Activity of Selenium and Lecithin Combination Against ethanol-induced Gastric Ulcer in mice via Modulating IGF-1/PTEN/Akt/FoxO3a Signaling |
Lemongrass Essential Oil | 📋 | ✍ | ⛔ | | 37749735 | Lemongrass Essential Oil Attenuates Perfluorooctane Sulfonate-Induced Jejunal Mucosal Injury in Rat: A Histological, Immunohistochemical, and Biochemical Study |
Maca Root | 📋 | ✍ | ⛔ | | 37955225 | The maca protein ameliorates DSS-induced colitis in mice by modulating the gut microbiota and production of SCFAs |
Mandarin | 📋 | | | | 35620406 | Citrus unshiu Peel Attenuates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice due to Modulation of the PI3K/Akt Signaling Pathway and MAPK and NF- κ B |
Mucuna Pruriens | 📋 | ✍ | ⛔ | | 37395947 | Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma |
Oak Gall | 📋 | ✍ | ⛔ | | 38638752 | Gastroprotective Effect of Quercus infectoria Olivier Galls on Ethanol-Induced Gastritis in Rats |
Parsley | 📋 | | ⛔ | | 37597227 | [The gastric regenerative effect of consumption of Petroselinum sativum L. (parsley) in rats with gastritis induced by ethanol] |
PEA | 📋 | ✍ | ⛔ | | 37599675 | Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism |
Peppermint | 📋 | ✍ | ⛔ | | 27912953 | Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial |
Pomelo | 📋 | | ⛔ | | 37419271 | Aqueous extract of pummelo pulp (Citrus maxima) improves the biochemical profile and reduces the inflammation process in Wistar rats with non-alcoholic fatty liver disease |
Prunella Vulgaris | 📋 | ✍ | ⛔ | | 38040415 | Exploring the mechanism of bioactive components of Prunella vulgaris L. in treating hepatocellular carcinoma based on network pharmacology |
Rapeseed Oil | 📋 | ✍ | | | 36691598 | Effects of Different Vegetable Oils on the Nonalcoholic Fatty Liver Disease in C57/BL Mice |
Rhodiola | 📋 | ✍ | ⛔ | | 36096243 | Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease |
Rosemary Essential Oil | 📋 | ✍ | ⛔ | | 38459835 | Rosemary essential oil potentiates the antitumour activity of 5-fluorouracil in human colorectal carcinoma cells |
Scutellarein | 📋 | | | | 34445559 | Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-κB Signaling through PTEN Activation in Hepatocellular Carcinoma |
Sea Cucumber | 📋 | | | | 38004208 | Sea Cucumber Peptides Ameliorate DSS-Induced Ulcerative Colitis: The Role of the Gut Microbiota, the Intestinal Barrier, and Macrophage Polarization |
Sesamolin | 📋 | | | | 36630317 | Sesamolin Attenuates Kidney Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat and High-Fructose Diet-Fed Mice |
Shilajit | 📋 | ✍ | ⛔ | | 35258780 | Protective Roles of Shilajit in Modulating Resistin, Adiponectin, and Cytokines in Rats with Non-alcoholic Fatty Liver Disease |
Sirtuin Activators | 📋 | | | | 36499440 | Sirtuins (SIRTs) As a Novel Target in Gastric Cancer |
Sodium Bicarbonate | 📋 | ✍ | ⛔ | | 36597048 | Prevention and the treatment of oral mucositis: the efficacy of sodium bicarbonate vs other agents: a systematic review |
Star Fuit | 📋 | | ⛔ | | 31704616 | Extract of Averrhoacarambola L. (Oxalidaceae) roots ameliorates carbon tetrachloride-induced hepatic fibrosis in rats |
Tamarind | 📋 | | ⛔ | | 37631047 | Tamarind Seed Polysaccharide Hydrolysate Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis via Regulating the Gut Microbiota |
Tea Tree Essential Oil | 📋 | | ⛔ | | 35155524 | Tea Tree Oil Terpinen-4-ol Protects Gut Barrier Integrity by Upregulation of Tight Junction Proteins via the ERK1/2-Signaling Pathway |
Theobromine | 📋 | ✍ | ⛔ | | 33360052 | Oncopreventive effects of theanine and theobromine on dimethylhydrazine-induced colon cancer model |
Turkey Tail Mushrooms | 📋 | | ⛔ | | 35204289 | Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect |
Vitamin B7 | 📋 | ✍ | ⛔ | | 38140308 | Clinical Implications of Dietary Probiotic Supplement (Associated with L-Glutamine and Biotin) in Ulcerative Colitis Patients' Body Composition and Quality of Life |
Vitamin B8 | 📋 | ✍ | ⛔ | | 36963888 | Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial |
Vitamin K1 | 📋 | ✍ | ⛔ | | 36648304 | Effect of phylloquinone on indomethacin-induced gastric ulceration in rats: Role of SIRT-1 |
Yohimbine | 📋 | ✍ | | | 37952411 | Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway |
5-HTP | 📋 | ✍ | ⛔ | | 35572711 | Oral Administration of 5-Hydroxytryptophan Restores Gut Microbiota Dysbiosis in a Mouse Model of Depression |
Activated Charcoal | 📋 | ✍ | ⛔ | | 36132707 | Dose-dependent Action of Zingiber officinale on Colonic Dysmotility and Ex Vivo Spontaneous Intestinal Contraction Modulation |
Aloesin | 📋 | | | | 21277867 | Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model |
Arctiin | 📋 | | | | 38205087 | Role of Arctiin in Fibrosis and Apoptosis in Experimentally Induced Hepatocellular Carcinoma in Rats |
Ashitaba | 📋 | ✍ | ⛔ | | 37920601 | Exploring the underlying mechanisms of Ashitaba in the management of non-alcoholic fatty liver disease by integrating the analysis of transcriptomics and metabolomics |
Avocado Oil | 📋 | | ⛔ | | 36601051 | Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet |
Bacopa Monnieri | 📋 | ✍ | ⛔ | | 37951147 | Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma |
Black Pepper Essential Oil | 📋 | | ⛔ | | 36076569 | Black pepper oil (Piper nigrum L.) mitigates dexamethasone induced pancreatic damage via modulation of oxidative and nitrosative stress |
Brussels Sprouts | 📋 | | ⛔ | | 35057085 | The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics |
Cauliflower | 📋 | | ⛔ | | 36429638 | Isothiocyanate-Rich Extracts from Cauliflower ( Brassica oleracea Var. Botrytis) and Radish ( Raphanus sativus) Inhibited Metabolic Activity and Induced ROS in Selected Human HCT116 and HT-29 Colorectal Cancer Cells |
Chamomile Essential Oil | 📋 | ✍ | ⛔ | | 29681854 | Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles |
Cloudberry | 📋 | | | | 27270323 | Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice |
Coriander Essential Oil | 📋 | ✍ | ⛔ | | 24901768 | Coriandrum sativum L. (Coriander) essential oil: antifungal activity and mode of action on Candida spp., and molecular targets affected in human whole-genome expression |
Corn | 📋 | | ⛔ | | 35761543 | Black corn (Zea mays L.) soluble extract showed anti-inflammatory effects and improved the intestinal barrier integrity in vivo (Gallus gallus) |
Cumin | 📋 | | ⛔ | | 34328087 | Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats |
Dragon Fruit | 📋 | | ⛔ | | 37087207 | Effects of dragon fruit oligosaccharides on immunity, gut microbiome, and their metabolites in healthy adults - A randomized double-blind placebo controlled study |
Essential Fatty Acids | 📋 | ✍ | | | 35765549 | Antimicrobial activities of microbial essential fatty acid against foodborne pathogenic bacteria |
Eucalyptol | 📋 | | | | 37047133 | Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation |
Eurycomanone | 📋 | | | | 35889271 | A Quassinoid Diterpenoid Eurycomanone from Eurycoma longifolia Jack Exerts Anti-Cancer Effect through Autophagy Inhibition |
Evening Primrose Oil | 📋 | ✍ | ⛔ | | 36239291 | Evening primrose seed extract rich in polyphenols modulates the invasiveness of colon cancer cells by regulating the TYMS expression |
Fat | 📋 | | | | 33603741 | Regulation of Intestinal Inflammation by Dietary Fats |
Glutathione | 📋 | ✍ | ⛔ | | 36548773 | Epigallocatechin Gallate and Glutathione Attenuate Aflatoxin B1-Induced Acute Liver Injury in Ducklings via Mitochondria-Mediated Apoptosis and the Nrf2 Signalling Pathway |
Grape Seed Oil | 📋 | | ⛔ | | 38278024 | The black Vitis vinifera seed oil saponifiable fraction ameliorates hepatocellular carcinoma in vitro and in vivo via modulating apoptosis and ROS/NF-κB signaling |
Grapefruit | 📋 | | ⛔ | | 27166529 | Anti-inflammatory effects of Citrus sinensis L., Citrus paradisi L. and their combinations |
Hemp Oil | 📋 | ✍ | ⛔ | | 36734470 | Integration of transcriptomics and metabonomics revealed the protective effects of hemp seed oil against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice |
Horsetail Grass | 📋 | ✍ | ⛔ | | 35789647 | Dose-Dependent Variation in Anticancer Activity of Hexane and Chloroform Extracts of Field Horsetail Plant on Human Hepatocarcinoma Cells |
Indian Barberry | 📋 | ✍ | ⛔ | | 31888241 | Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial |
L-Histidine | 📋 | ✍ | ⛔ | | 37174059 | Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant-Antioxidant Balance |
L-Leucine | 📋 | ✍ | ⛔ | | 35245436 | Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination |
L-Proline | 📋 | ✍ | ⛔ | | 20693968 | In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1 |
Lime | 📋 | | ⛔ | | 37049726 | Metabolomic Analysis of Phytochemical Compounds from Ethanolic Extract of Lime ( Citrus aurantifolia) Peel and Its Anti-Cancer Effects against Human Hepatocellular Carcinoma Cells |
Mango Leaf | 📋 | | ⛔ | | 33167456 | Metabolomic Profiling of Mango ( Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models |
Neem Oil | 📋 | ✍ | ⛔ | | 31875751 | Use of Neem Oil and Hypericum perforatum for Treatment of Calcinosis-Related Skin Ulcers in Systemic Sclerosis |
Neohesperidin | 📋 | | | | 38226659 | Orally administered neohesperidin attenuates MPTP-induced neurodegeneration by inhibiting inflammatory responses and regulating intestinal flora in mice |
Nootkatone | 📋 | | | | 36671056 | Nootkatone Supplementation Ameliorates Carbon Tetrachloride-Induced Acute Liver Injury via the Inhibition of Oxidative Stress, NF-κB Pathways, and the Activation of Nrf2/HO-1 Pathway |
Oak Acorn | 📋 | ✍ | ⛔ | | 35076295 | Prophylactic Protective Action of Aqueous Extract of Green Oak Acorns on Ethanol-Induced Acute Injury to Rat Gastroduodenal Mucosa |
Oak Bark | 📋 | ✍ | ⛔ | | 31100197 | Purpurogallin is a novel mitogen-activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo |
Pear | 📋 | | ⛔ | | 33809380 | Protective Effect of Pyrus ussuriensis Maxim. Extract against Ethanol-Induced Gastritis in Rats |
Pecan | 📋 | | ⛔ | | 37299553 | Pecans and Its Polyphenols Prevent Obesity, Hepatic Steatosis and Diabetes by Reducing Dysbiosis, Inflammation, and Increasing Energy Expenditure in Mice Fed a High-Fat Diet |
Phytosterols | 📋 | | | | 37756430 | Phytosterols Protect against Osteoporosis by Regulating Gut Microbiota |
Polypodium Leucotomos | 📋 | ✍ | ⛔ | | 36686704 | Polypodium leucotomos targets multiple aspects of oral carcinogenesis and it is a potential antitumor phytotherapy against tongue cancer growth |
Potassium | 📋 | ✍ | ⛔ | | 38635545 | Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States |
Progesterone | 📋 | ✍ | ⛔ | | 36263327 | Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males |
Pumpkin | 📋 | | ⛔ | | 34805250 | Sequential Extraction, Characterization, and Analysis of Pumpkin Polysaccharides for Their Hypoglycemic Activities and Effects on Gut Microbiota in Mice |
Pumpkin Seed | 📋 | ✍ | ⛔ | | 30245714 | An Appraisal of Pumpkin Seed Extract in 1, 2-Dimethylhydrazine Induced Colon Cancer in Wistar Rats |
Pumpkin Seed Oil | 📋 | ✍ | ⛔ | | 26405765 | Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil |
Pyridoxal-5-Phosphate | 📋 | ✍ | ⛔ | | 24183308 | Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease |
Rosavin | 📋 | | ⛔ | | 36077546 | Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death |
Rosehip | 📋 | ✍ | ⛔ | | 32379993 | Chemical Characterization of Bioactive Components of Rosa canina Extract and Its Protective Effect on Dextran Sulfate Sodium-Induced Intestinal Bowel Disease in a Mouse Model |
Rye | 📋 | | ⛔ | | 37905980 | Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in adults |
Sage Essential Oil | 📋 | | ⛔ | | 32531144 | Antiproliferative Effect and Cell Cycle Alterations Induced by Salvia Officinalis Essential Oil and Its Three Main Components in Human Colon Cancer Cell Lines |
Soybean Oil | 📋 | | ⛔ | | 35276916 | A Lard and Soybean Oil Mixture Alleviates Low-Fat-High-Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease in Mice |
Spearmint Essential Oil | 📋 | ✍ | ⛔ | | 34201645 | Mint Oils: In Vitro Ability to Perform Anti-Inflammatory, Antioxidant, and Antimicrobial Activities and to Enhance Intestinal Barrier Integrity |
Sugarcane | 📋 | | ⛔ | | 30946967 | A randomized controlled double blinded trial to evaluate efficacy of oral administration of black strap molasses (sugarcane extract) in comparison with polyethylene glycol on pediatric functional constipation |
Tangerine | 📋 | | ⛔ | | 35027935 | Scutellariae Radix and Citri Reticulatae Pericarpium Mixture Regulate PPAR γ/RXR Signaling in Reflux Esophagitis |
Tongkat Ali | 📋 | ✍ | ⛔ | | 37511840 | Anti-Inflammatory, Antinociceptive, Antipyretic, and Gastroprotective Effects of Eurycoma longifolia Jack Ethanolic Extract |
Vitamin K2 mk-7 | 📋 | ✍ | | | 37257737 | Neuroprotective effect of Vitamin K2 against gut dysbiosis associated cognitive decline |
Wheat | 📋 | | ⛔ | | 37814914 | Effect of red wheat, aleurone, and testa layers on colon cancer biomarkers, nitrosative stress, and gut microbiome composition in rats |
Acemannan | 📋 | | | | 29072072 | Acemannan and Fructans From Aloe Vera (Aloe Barbadensis Miller) Plants as Novel Prebiotics |
Alfalfa | 📋 | | ⛔ | | 37860685 | Gastroprotective evaluation of Medicago sativa L. (Fabaceae) on diabetic rats |
Almond Oil | 📋 | | ⛔ | | 35774276 | Comparison of the Effects of Abdominal Massage and Oral Administration of Sweet Almond Oil on Constipation and Quality of Life among Elderly Individuals: A Single-Blind Clinical Trial |
Alpha GPC | 📋 | ✍ | ⛔ | | 27861548 | Targeting Mitochondrial Dysfunction with L-Alpha Glycerylphosphorylcholine |
Amaranth | 📋 | | ⛔ | | 35186332 | The Role of Pseudocereals in Celiac Disease: Reducing Nutritional Deficiencies to Improve Well-Being and Health |
Amino Acids | 📋 | | | | 35786467 | [Regulation of inflammatory bowel disease by amino acids] |
Apricot Oil | 📋 | | ⛔ | | 30234391 | Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats |
Arachidonic Acid | 📋 | ✍ | ⛔ | | 33209199 | Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells |
Azadirachtin | 📋 | | | | 34944759 | Azadirachtin Attenuates Lipopolysaccharide-Induced ROS Production, DNA Damage, and Apoptosis by Regulating JNK/Akt and AMPK/mTOR-Dependent Pathways in Rin-5F Pancreatic Beta Cells |
Beer | 📋 | | | | 36839202 | Beer and Microbiota: Pathways for a Positive and Healthy Interaction |
Black Ginger | 📋 | ✍ | ⛔ | | 33503922 | Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora |
Bladderwrack | 📋 | ✍ | ⛔ | | 37755091 | Bioactivity of Fucoidan-Rich Extracts from Fucus vesiculosus against Rotavirus and Foodborne Pathogens |
Brazil Nut | 📋 | | ⛔ | | 27923410 | Supplementation With Brazil Nuts and Green Tea Extract Regulates Targeted Biomarkers Related to Colorectal Cancer Risk in Humans |
Butter | 📋 | | ⛔ | | 34579147 | Ghee Butter from Bovine Colostrum Reduces Inflammation in the Mouse Model of Acute Pancreatitis with Potential Involvement of Free Fatty Acid Receptors |
Calcium D-Glucarate | 📋 | ✍ | ⛔ | | 20393005 | Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation |
Camphor | 📋 | ✍ | ⛔ | | 35866389 | Camphor Seed Kernel Oil Beneficial Effects the Gut Microbiota of the Non-Alcoholic Fatty Liver Disease Mice |
Captopril | 📋 | | | | 38542253 | Renin-Angiotensin Inhibitor, Captopril, Attenuates Growth of Patient-Derived Colorectal Liver Metastasis Organoids |
Caraway | 📋 | | ⛔ | | 35255832 | A novel duodenal-release formulation of caraway oil and L-menthol is a safe, effective and well tolerated therapy for functional dyspepsia |
Cashew | 📋 | | ⛔ | | 35028183 | Evaluation of the gastrointestinal anti-motility effect of Anacardium occidentale stem bark extract: A mechanistic study of antidiarrheal activity |
Cedarwood Essential Oil | 📋 | ✍ | ⛔ | | 32013183 | The In Vitro Activity of Essential Oils against Helicobacter Pylori Growth and Urease Activity |
Chebulinic Acid | 📋 | | | | 35075915 | Gastric ulcer healing by chebulinic acid solid dispersion-loaded gastroretentive raft systems: preclinical evidence |
Cheese | 📋 | | ⛔ | | 21235114 | Risk factors for colorectal polyps: findings from a Greek case-control study |
Chickpea | 📋 | | ⛔ | | 37375942 | Chemopreventive Effect of Cooked Chickpea on Colon Carcinogenesis Evolution in AOM/DSS-Induced Balb/c Mice |
Chromium | 📋 | ✍ | ⛔ | | 33312555 | An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice |
Collagen | 📋 | ✍ | | | 35639457 | Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study |
Cucumber | 📋 | | ⛔ | | 34832981 | Cucumis sativus L. Seeds Ameliorate Muscular Spasm-Induced Gastrointestinal and Respiratory Disorders by Simultaneously Inhibiting Calcium Mediated Signaling Pathway |
DMAE | 📋 | ✍ | ⛔ | | 1646761 | Improvement of estradiol 17 beta-D-glucuronide cholestasis by intravenous administration of dimethylethanolamine in the rat |
Eclipta Alba | 📋 | ✍ | | | 35337710 | Anti-inflammatory effect of wedelolactone on DSS induced colitis in rats: IL-6/STAT3 signaling pathway |
Equol | 📋 | ✍ | ⛔ | | 37565591 | Association between equol and non-alcoholic fatty liver disease in Japanese women in their 50s and 60s |
Eucalyptus Essential Oil | 📋 | | ⛔ | | 33660226 | In Vitro Cytotoxicity and Apoptotic Assay of Eucalyptus globulus Essential Oil in Colon and Liver Cancer Cell Lines |
Flavones | 📋 | | | | 37324477 | Natural flavones from edible and medicinal plants exhibit enormous potential to treat ulcerative colitis |
Fluted Gourd | 📋 | | | | 34331468 | Telfairia occidentalis mitigates dextran sodium sulfate-induced ulcerative colitis in rats via suppression of oxidative stress, lipid peroxidation, and inflammation |
GABA | 📋 | ✍ | ⛔ | | 38193198 | Experimental colitis-induced visceral hypersensitivity is attenuated by GABA-treatment in mice |
Geranium | 📋 | | | | 32492494 | Geranium koreanum, a medicinal plant Geranii Herba, ameliorate the gastric mucosal injury in gastritis-induced mice |
Helichrysum | 📋 | | ⛔ | | 24140587 | Intestinal antispasmodic effects of Helichrysum italicum (Roth) Don ssp. italicum and chemical identification of the active ingredients |
Hops | 📋 | ✍ | ⛔ | | 35229981 | Xanthohumol targets the JNK1/2 signaling pathway in apoptosis of human nasopharyngeal carcinoma cells |
Horse Chestnut | 📋 | ✍ | ⛔ | | 34275854 | In vitro antioxidant potential and antiproliferative activity of Aesculus indica seed extract against hepatocellular carcinoma cell line |
Hyssop | 📋 | ✍ | ⛔ | | 31694395 | Gastroprotective effect of Hyssopus officinalis L. leaves via reduction of oxidative stress in indomethacin-induced gastric ulcer in experimental rats |
Isoflavones | 📋 | ✍ | ⛔ | | 32548137 | Isoflavones and inflammatory bowel disease |
L-Alanine | 📋 | ✍ | ⛔ | | 35698613 | Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis |
L-Tyrosine | 📋 | ✍ | ⛔ | | 37490119 | Dietary antioxidant quercetin overcomes the acquired resistance of Sorafenib in Sorafenib-resistant hepatocellular carcinoma cells through epidermal growth factor receptor signaling inactivation |
Lemon Balm Essential Oil | 📋 | ✍ | ⛔ | | 32041100 | Methylcellulose Hydrogel with Melissa officinalis Essential Oil as a Potential Treatment for Oral Candidiasis |
Lemon Verbena | 📋 | | ⛔ | | 33489039 | Gastroprotective effects of both aqueous and ethanolic extracts of Lemon verbena leaves against indomethacin-induced gastric ulcer in rats |
Lettuce | 📋 | | ⛔ | | 36296971 | Molecular Effects of Iodine-Biofortified Lettuce in Human Gastrointestinal Cancer Cells |
Lipase | 📋 | ✍ | ⛔ | | 25287168 | Lipase Supplementation before a High-Fat Meal Reduces Perceptions of Fullness in Healthy Subjects |
Long Pepper | 📋 | | ⛔ | | 31281405 | Prebiotic Potential of Culinary Spices Used to Support Digestion and Bioabsorption |
Madecassoside | 📋 | | | | 34180971 | Importance of telomere shortening in the pathogenesis of ulcerative colitis: A new treatment from the aspect of telomeres in intestinal epithelial cells |
Mandarin Essential Oil | 📋 | | ⛔ | | 35642325 | GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori |
Marshmallow Root | 📋 | | ⛔ | | 30554882 | A randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years |
Matcha Tea | 📋 | | | | 36936880 | A randomized, double-blinded study evaluating effect of matcha green tea on human fecal microbiota |
Mint | 📋 | | ⛔ | | 27282663 | Mentha longifolia protects against acetic-acid induced colitis in rats |
MUFA | 📋 | | ⛔ | | 35220970 | Dietary intake of monounsaturated and polyunsaturated fatty acids is related to the reduced risk of esophageal squamous cell carcinoma |
Nitrate | 📋 | ✍ | ⛔ | | 38733290 | Effects of dietary nitrate supplementation on oral health and associated markers of systemic health: a systematic review |
Olive | 📋 | ✍ | ⛔ | | 36262974 | Antioxidant and Anticancer Potentials of the Olive and Sesame Mixture against Dimethylhydrazine-Induced Colorectal Cancer in Wistar Rats |
Pantethine | 📋 | ✍ | ⛔ | | 11425046 | The effects of pantethine on fatty liver and fat distribution |
Peas | 📋 | | ⛔ | | 35262351 | Polyphenol Content of Green Pea ( Pisum sativum L.) Hull under In Vitro Digestion and Effects of Digestive Products on Anti-Inflammatory Activity and Intestinal Barrier in the Caco-2/Raw264.7 Coculture Model |
Pelargonidin | 📋 | | | | 31696323 | Pelargonidin 3-glucoside-enriched Strawberry Attenuates Symptoms of DSS-induced Inflammatory Bowel Disease and Diet-Induced Metabolic Syndrome in Rats |
Phellodendron | 📋 | ✍ | ⛔ | | 35463358 | Mechanism of Phellodendron and Anemarrhena Drug Pair on the Treatment of Liver Cancer Based on Network Pharmacology and Bioinformatics |
Phosphatidylserine | 📋 | ✍ | ⛔ | | 33977946 | DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet |
Phytoestrogens | 📋 | | ⛔ | | 37719855 | Protective effect of phytoestrogens on nonalcoholic fatty liver disease in postmenopausal women |
Pine Needle Essential Oil | 📋 | ✍ | ⛔ | | 19112901 | [Apoptosis and activity changes of telomerase induced by essential oil from pine needles in HepG2 cell line] |
Rose Essential Oil | 📋 | | | | 38222701 | Effect of aromatherapy with rose essential oil on the nausea and vomiting in chemotherapy patients: a randomized controlled trial |
Seafood | 📋 | | | | 32770320 | Omega-3 polyunsaturated fatty acids: a promising approach for the management of oral lichen planus |
St. Johns Wort Oil | 📋 | | ⛔ | | 31875751 | Use of Neem Oil and Hypericum perforatum for Treatment of Calcinosis-Related Skin Ulcers in Systemic Sclerosis |
Sulfur | 📋 | ✍ | ⛔ | | 34725578 | Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb®) in Relieving Constipation |
Sunflower | 📋 | | ⛔ | | 34521318 | Helianthus Annuus L. Alleviates High-Fat Diet Induced Atherosclerosis by Regulating Intestinal Microbiota, Inhibiting Inflammation and Restraining Oxidative Stress |
Terpenoids | 📋 | | | | 36615471 | Terpenoids: Natural Compounds for Non-Alcoholic Fatty Liver Disease (NAFLD) Therapy |
Toothache Plant | 📋 | | | | 37671677 | The potential of Acmella oleracea as a nutraceutical source for the symptomatic treatment of Burning Mouth Syndrome |
Vitamin B5 | 📋 | ✍ | ⛔ | | 1810066 | [The use of pantothenic acid preparations in treating patients with viral hepatitis A] |
Water Chestnut | 📋 | ✍ | ⛔ | | 35208513 | Evaluation of Dose-Dependent Obesity and Diabetes-Related Complications of Water Chestnut (Fruit of Trapa japonica) Extracts in Type II Obese Diabetic Mice Induced by 45% Kcal High-Fat Diet |
Watercress | 📋 | ✍ | ⛔ | | 37057243 | Effect of Nasturtium Extract on Oral Cancer |
Witch Hazel | 📋 | ✍ | ⛔ | | 22216935 | Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells |
Wood Ear Mushrooms | 📋 | | ⛔ | | 34787328 | Auricularia auricula-judae (Bull.) polysaccharides improve type 2 diabetes in HFD/STZ-induced mice by regulating the AKT/AMPK signaling pathways and the gut microbiota |
Wormwood Essential Oil | 📋 | | ⛔ | | 34268303 | Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway |
Xylitol | 📋 | ✍ | ⛔ | | 35631164 | Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer |
Yerba Mate | 📋 | ✍ | ⛔ | | 29548463 | Optimized Camellia sinensis var. sinensis, Ilex paraguariensis, and Aspalathus linearis blend presents high antioxidant and antiproliferative activities in a beverage model |
Yiang Yiang Essential Oil | 📋 | | ⛔ | | 31956259 | Antiviral Activity of Cananga odorata Against Hepatitis B Virus |